Annals of the New York Academy of Sciences

Cover image for Vol. 1068 Skeletal Development and Remodeling in Health, Disease, and Aging

April 2006

Volume 1068 Skeletal Development and Remodeling in Health, Disease, and Aging

Pages xiii–xviii, 1–575

  1. In Memorium

    1. Top of page
    2. In Memorium
    3. Editorial
    4. Part I. Skeletal Development
    5. Part II. Skeletal Remodeling
    6. Part III. Mechanisms of Bone Loss
    7. Index of Contributors
  2. Editorial

    1. Top of page
    2. In Memorium
    3. Editorial
    4. Part I. Skeletal Development
    5. Part II. Skeletal Remodeling
    6. Part III. Mechanisms of Bone Loss
    7. Index of Contributors
  3. Part I. Skeletal Development

    1. Top of page
    2. In Memorium
    3. Editorial
    4. Part I. Skeletal Development
    5. Part II. Skeletal Remodeling
    6. Part III. Mechanisms of Bone Loss
    7. Index of Contributors
    1. PTHrP and Skeletal Development (pages 1–13)

      HENRY M. KRONENBERG

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.002

    2. BMP Signaling and Skeletogenesis (pages 26–40)

      XUELIN LI and XU CAO

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.006

    3. Dysregulation of the BMP-4 Signaling Pathway in Fibrodysplasia Ossificans Progressiva (pages 54–65)

      FREDERICK S. KAPLAN, JENNIFER FIORI, LOURDES SERRANO DE LA PEÑA, JAIMO AHN, PAUL C. BILLINGS and EILEEN M. SHORE

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.008

    4. Cellular and Molecular Mechanisms of Synovial Joint and Articular Cartilage Formation (pages 74–86)

      MAURIZIO PACIFICI, EIKI KOYAMA, YOSHIHIRO SHIBUKAWA, CHANGSHAN WU, YOSHIHIRO TAMAMURA, MOTOMI ENOMOTO-IWAMOTO and MASAHIRO IWAMOTO

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.010

    5. Multiple Roles of Hoxc8 in Skeletal Development (pages 87–94)

      ASTER H. JUAN, HAIYAN LEI, PRERNA BHARGAVA, MARIELLE LEBRUN and FRANK H. RUDDLE

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.046

  4. Part II. Skeletal Remodeling

    1. Top of page
    2. In Memorium
    3. Editorial
    4. Part I. Skeletal Development
    5. Part II. Skeletal Remodeling
    6. Part III. Mechanisms of Bone Loss
    7. Index of Contributors
    1. Osteoclasts and Integrins (pages 95–99)

      STEVEN L. TEITELBAUM

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.017

    2. Molecular Mechanism of the Life and Death of the Osteoclast (pages 180–186)

      SAKAE TANAKA, TSUYOSHI MIYAZAKI, AKIRA FUKUDA, TORU AKIYAMA, YUHO KADONO, HIDETOSHI WAKEYAMA, SHINJIRO KONO, SHINYA HOSHIKAWA, MASAKI NAKAMURA, YASUSHI OHSHIMA, ATSUHIKO HIKITA, ICHIRO NAKAMURA and KOZO NAKAMURA

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.020

    3. Understanding Parathyroid Hormone Action (pages 187–193)

      NICOLA C. PARTRIDGE, XIN LI and LING QIN

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.024

    4. New Insights into the Mechanisms Involved in the Pleiotropic Actions of 1,25Dihydroxyvitamin D3 (pages 194–203)

      SYLVIA CHRISTAKOS, PUNEET DHAWAN, QI SHEN, XIAORONG PENG, BRYAN BENN and YAN ZHONG

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.025

    5. Role of Connexin43 in Osteoblast Response to Physical Load (pages 214–224)

      SUSAN K. GRIMSTON, JOANNE SCREEN, JENNIFER H. HASKELL, DONG JIN CHUNG, MICHAEL D. BRODT, MATTHEW J. SILVA and ROBERTO CIVITELLI

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.023

    6. Eosinophil Chemotactic Factor-L (ECF-L) Enhances Osteoclast Formation by Increasing ICAM-1 Expression (pages 240–243)

      VERONICA GARCIA PALACIOS, HO YEON CHUNG, SUN JIN CHOI, NORIYOSHI KURIHARA, JUN WON LEE, LORI A. EHRLICH, ROBERT COLLINS and G. DAVID ROODMAN

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.048

  5. Part III. Mechanisms of Bone Loss

    1. Top of page
    2. In Memorium
    3. Editorial
    4. Part I. Skeletal Development
    5. Part II. Skeletal Remodeling
    6. Part III. Mechanisms of Bone Loss
    7. Index of Contributors
    1. Bone Cell Precursors and the Pathophysiology of Bone Loss (pages 244–249)

      HARRY C. BLAIR and JILL L. CARRINGTON

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.028

    2. Estrogen Regulation of Immune Cell Bone Interactions (pages 256–274)

      M. NEALE WEITZMANN and ROBERTO PACIFICI

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.030

    3. Autoimmunity and Bone (pages 275–283)

      EDWARD M. SCHWARZ, R. JOHN LOONEY, M. HICHAM DRISSI, REGIS J. O'KEEFE, BRENDAN F. BOYCE, LIANPING XING and CHRISTOPHER T. RITCHLIN

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.031

    4. Nonsteroid Immune Modulators and Bone Disease (pages 284–296)

      RONALD TAMLER and SOLOMON EPSTEIN

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.032

    5. Pathogenesis of Osteopenia/Osteoporosis Induced by Highly Active Anti-Retroviral Therapy for AIDS (pages 297–308)

      GEORGE PAN, ZHEN YANG, SCOTT W. BALLINGER and JAY M. MCDONALD

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.057

    6. TSH and Bone Loss (pages 309–318)

      LI SUN, TERRY F. DAVIES, HARRY C. BLAIR, ETSUKO ABE and MONE ZAIDI

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.033

    7. Bone Destruction in Multiple Myeloma (pages 319–326)

      TOSHIO MATSUMOTO and MASAHIRO ABE

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.035

    8. Osteogenic Regulation of Vascular Calcification (pages 327–333)

      DWIGHT A. TOWLER, JIAN-SU SHAO, SU-LI CHENG, JOYCE M. PINGSTERHAUS and ARLEEN P. LOEWY

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.036

    9. The Role of OPG/TRAIL Complex in Multiple Myeloma : The OPG/TRAIL Complex in an In Vitro Osteoclastogenesis Model Derived From Human Multiple Myeloma-Bone Disease (pages 334–340)

      GIACOMINA BRUNETTI, SILVIA COLUCCI, RITA RIZZI, GIORGIO MORI, GRAZIANA COLAIANNI, ANGELA ORANGER, ALBERTA ZALLONE, VINCENZO LISO and MARIA GRANO

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.049

    10. Restoration of Bone Mass in Hpg Mouse by Preoptic Area Grafting (pages 341–347)

      GOPALAN RAJENDREN, HANG ZHOU, BALJIT S. MOONGA, MONE ZAIDI and LI SUN

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.050

    11. IL-7 Drives T Cell-Mediated Bone Loss Following Ovariectomy (pages 348–351)

      MICHAELA ROBBIE-RYAN, ROBERTO PACIFICI and M. NEALE WEITZMANN

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.051

    12. Novel Targets and Therapeutics for Bone Loss (pages 402–409)

      RONALD N. MARGOLIS and SUNIL J. WIMALAWANSA

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.040

    13. Advanced Imaging Assessment of Bone Quality (pages 410–428)

      HARRY K. GENANT and YEBIN JIANG

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.038

    14. Bone Strength: Current Concepts (pages 429–446)

      CHARLES H. TURNER

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.039

    15. Future Anti-Catabolic Therapeutic Targets in Bone Disease (pages 447–457)

      BRENDAN F. BOYCE, LIANPING XING, ZHENQIANG YAO, WILLIAM C. SHAKESPEARE, YIHAN WANG, CHESTER A. METCALF III, RAJI SUNDARAMOORTHI, DAVID C. DALGARNO, JOHN D. IULIUCCI and TOMI K. SAWYER

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.042

    16. Mechanisms Involved in Skeletal Anabolic Therapies (pages 458–470)

      T.J. MARTIN, J.M.W. QUINN, M.T. GILLESPIE, K.W. NG, M.A. KARSDAL and N.A. SIMS

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.043

    17. Circulating Cells with Osteogenic Potential (pages 489–497)

      SUNDEEP KHOSLA and GUITI Z. EGHBALI-FATOURECHI

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.022

    18. The Pericellular Matrix as a Transducer of Biomechanical and Biochemical Signals in Articular Cartilage (pages 498–512)

      FARSHID GUILAK, LEONIDAS G. ALEXOPOULOS, MAUREEN L. UPTON, INCHAN YOUN, JAE BONG CHOI, LI CAO, LORI A. SETTON and MANSOOR A. HAIDER

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.011

    19. Clinical Biophysics: The Promotion of Skeletal Repair by Physical Forces (pages 513–531)

      ROY K. AARON, DEBORAH McK. CIOMBOR, SHUO WANG and BRUCE SIMON

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.045

    20. COX-2 has a Critical Role During Incorporation of Structural Bone Allografts (pages 532–542)

      REGIS J. O'KEEFE, PRAROP TIYAPATANAPUTI, CHAO XIE, TIAN FANG LI, CHRIS CLARK, MICHEAL J. ZUSCIK, DI CHEN, HICHAM DRISSI, EDWARD SCHWARZ and XINPING ZHANG

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.012

    21. The Effect of Anti-TNF-α Therapy on Spinal Bone Mineral Density in Patients with Crohn's Disease (pages 543–556)

      MICHAEL PAZIANAS, ANDREW D. RHIM, ANDREW M. WEINBERG, CHINYU SU and GARY R. LICHTENSTEIN

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.055

    22. NFATc1: A Novel Anabolic Therapeutic Target for Osteoporosis (pages 564–567)

      HYEONJU YEO, JAY M. MCDONALD and MAJD ZAYZAFOON

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.053

    23. Mechanical Loading Differentially Regulates Membrane-Bound and Soluble RANKL Availability in MC3T3-E1 Cells (pages 568–572)

      DAE WON KIM, HAHN-JUN LEE, JAIME A. KARMIN, SE EUN LEE, SEONG-SIL CHANG, BEN TOLCHIN, SHIPHIN LIN, SAM K. CHO, ANTHONY KWON, JAE MOK AHN and FRANCIS YOUNG-IN LEE

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.054

  6. Index of Contributors

    1. Top of page
    2. In Memorium
    3. Editorial
    4. Part I. Skeletal Development
    5. Part II. Skeletal Remodeling
    6. Part III. Mechanisms of Bone Loss
    7. Index of Contributors
    1. Index of Contributors (pages 573–575)

      Article first published online: 30 MAY 2006 | DOI: 10.1196/annals.1346.692

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