Annals of the New York Academy of Sciences

Cover image for Vol. 1079 Immunology of Diabetes IV: Progress in Our Understanding

October 2006

Volume 1079 Immunology of Diabetes IV: Progress in Our Understanding

Pages xv–xv, 1–401

  1. Overview

    1. Top of page
    2. Overview
    3. Part I. Special Papers
    4. Part II. Diabetes in Asia
    5. Part III. Latent Autoimmune Diabetes in Adults
    6. Part IV. Animal Models
    7. Part V. T Cells
    8. Part VI. Autoantibodies
    9. Part VII. Genetics
    10. Part VIII. Prediction and Prevention
    11. Index of Contributors
    1. Overview (page xv)

      C.B. Sanjeevi and T. Hanafusa

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.060

  2. Part I. Special Papers

    1. Top of page
    2. Overview
    3. Part I. Special Papers
    4. Part II. Diabetes in Asia
    5. Part III. Latent Autoimmune Diabetes in Adults
    6. Part IV. Animal Models
    7. Part V. T Cells
    8. Part VI. Autoantibodies
    9. Part VII. Genetics
    10. Part VIII. Prediction and Prevention
    11. Index of Contributors
    1. The Type 1 Diabetes Genetics Consortium (pages 1–8)

      STEPHEN S. RICH, PATRICK CONCANNON, HENRY ERLICH, CECILE JULIER, GRANT MORAHAN, JORN NERUP, FLEMMING POCIOT and JOHN A. TODD

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.001

  3. Part II. Diabetes in Asia

    1. Top of page
    2. Overview
    3. Part I. Special Papers
    4. Part II. Diabetes in Asia
    5. Part III. Latent Autoimmune Diabetes in Adults
    6. Part IV. Animal Models
    7. Part V. T Cells
    8. Part VI. Autoantibodies
    9. Part VII. Genetics
    10. Part VIII. Prediction and Prevention
    11. Index of Contributors
    1. Genetics of Fulminant Type 1 Diabetes (pages 24–30)

      EIJI KAWASAKI and KATSUMI EGUCHI

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.004

    2. Association of SUMO4, as a Candidate Gene for IDDM5, with Susceptibility to Type 1 Diabetes in Asian Populations (pages 41–46)

      SHINSUKE NOSO, HIROSHI IKEGAMI, TOMOMI FUJISAWA, YUMIKO KAWABATA, KATSUAKI ASANO, YOSHIHISA HIROMINE, SHIGETAKA SUGIHARA, INKYU LEE, EIJI KAWASAKI, TAKUYA AWATA and TOSHIO OGIHARA

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.006

    3. The Gene for Human IL-21 and Genetic Susceptibility to Type 1 Diabetes in the Japanese (pages 47–50)

      KATSUAKI ASANO, HIROSHI IKEGAMI, TOMOMI FUJISAWA, YUMIKO KAWABATA, SHINSUKE NOSO, YOSHIHISA HIROMINE and TOSHIO OGIHARA

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.007

    4. Genetics of Type 1 Diabetes: Similarities and Differences between Asian and Caucasian Populations (pages 51–59)

      HIROSHI IKEGAMI, TOMOMI FUJISAWA, YUMIKO KAWABATA, SHINSUKE NOSO and TOSHIO OGIHARA

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.008

  4. Part III. Latent Autoimmune Diabetes in Adults

    1. Top of page
    2. Overview
    3. Part I. Special Papers
    4. Part II. Diabetes in Asia
    5. Part III. Latent Autoimmune Diabetes in Adults
    6. Part IV. Animal Models
    7. Part V. T Cells
    8. Part VI. Autoantibodies
    9. Part VII. Genetics
    10. Part VIII. Prediction and Prevention
    11. Index of Contributors
    1. Immunopathological and Genetic Features in Slowly Progressive Insulin-Dependent Diabetes Mellitus and Latent Autoimmune Diabetes in Adults (pages 60–66)

      TETSURO KOBAYASHI, SHOICHIRO TANAKA, NORIKAZU HARII, KAORU AIDA, HIROKI SHIMURA, MASAYUKI OHMORI, MASAHIRO KANESIGE, AKIRA SHIMADA and TARO MARUYAMA

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.009

  5. Part IV. Animal Models

    1. Top of page
    2. Overview
    3. Part I. Special Papers
    4. Part II. Diabetes in Asia
    5. Part III. Latent Autoimmune Diabetes in Adults
    6. Part IV. Animal Models
    7. Part V. T Cells
    8. Part VI. Autoantibodies
    9. Part VII. Genetics
    10. Part VIII. Prediction and Prevention
    11. Index of Contributors
    1. Heightened Interferon-α/β Response Causes Myeloid Cell Dysfunction and Promotes T1D Pathogenesis in NOD Mice (pages 99–102)

      RUI HUA PENG, EDWARD PAEK, CHANQING Q. XIA, NATHAN TENNYSON and MICHAEL J. CLARE-SALZLER

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.013

    2. Contribution of Class III MHC to Susceptibility to Type 1 Diabetes in the NOD Mouse (pages 114–117)

      KAORI YAMAJI, HIROSHI IKEGAMI, TOMOMI FUJISAWA, SHINSUKE NOSO, KOJI NOJIMA, NARU BABAYA, MICHIKO ITOI-BABAYA, MISATO KOBAYASHI, YOSHIHISA HIROMINE, SUSUMU MAKINO and TOSHIO OGIHARA

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.016

    3. MHC-Linked Susceptibility to Type 1 Diabetes in the NOD Mouse : Further Localization of Idd16 by Subcongenic Analysis (pages 118–121)

      TOMOMI FUJISAWA, HIROSHI IKEGAMI, SHINSUKE NOSO, KAORI YAMAJI, KOJI NOJIMA, NARU BABAYA, MICHIKO ITOI-BABAYA, YOSHIHISA HIROMINE, MISATO KOBAYASHI, SUSUMU MAKINO and TOSHIO OGIHARA

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.017

    4. Pancreatic Autoimmunity Induction with Insulin B:9–23 Peptide and Viral Mimics in the NZB Mouse (pages 135–137)

      DEVASENAN DEVENDRA, DONGMEI MIAO, MAKI NAKAYAMA, GEORGE S. EISENBARTH and EDWIN LIU

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.020

    5. Characterization of PAF-AH Ib1 in NOD Mice : PAF-AH May Not Be a Candidate Gene of the Diabetes Susceptibility Idd4.1 Locus (pages 147–152)

      QING-SHENG MI, LI ZHOU, MARSHA GRATTAN, ZAI-ZHAO WANG, M. SIVILOTTI, JING-XIANG SHE and TERRY L. DELOVITCH

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.022

  6. Part V. T Cells

    1. Top of page
    2. Overview
    3. Part I. Special Papers
    4. Part II. Diabetes in Asia
    5. Part III. Latent Autoimmune Diabetes in Adults
    6. Part IV. Animal Models
    7. Part V. T Cells
    8. Part VI. Autoantibodies
    9. Part VII. Genetics
    10. Part VIII. Prediction and Prevention
    11. Index of Contributors
    1. Metabolism Genes Are among the Differentially Expressed Ones Observed in Lymphomononuclear Cells of Recently Diagnosed Type 1 Diabetes Mellitus Patients (pages 171–176)

      DIANE M. RASSI, CRISTINA M. JUNTA, ANA LÚCIA FACHIN, PAULA SANDRIN-GARCIA, STEFANO MELLO, MÁRCIA M.C. MARQUES, ANA PAULA M. FERNANDES, MARIA CRISTINA FOSS-FREITAS, MILTON C. FOSS, ELZA T. SAKAMOTO-HOJO, GERALDO A.S. PASSOS and EDUARDO A. DONADI

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.026

    2. Expression Levels of CXC Chemokine Receptors 3 Are Associated with Clinical Phenotype of Type 1 Diabetes (pages 186–189)

      SATORU YAMADA, YOICHI OIKAWA, GEN SAKAI, YOSHIHITO ATSUMI, TARO MARUYAMA and AKIRA SHIMADA

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.029

    3. HLA Class I Epitope Discovery in Type 1 Diabetes (pages 190–197)

      PETER VAN ENDERT, YOUSRA HASSAINYA, VIVIAN LINDO, JEAN-MARIE BACH, PHILIPPE BLANCOU, FRANÇOIS LEMONNIER and ROBERTO MALLONE

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.030

  7. Part VI. Autoantibodies

    1. Top of page
    2. Overview
    3. Part I. Special Papers
    4. Part II. Diabetes in Asia
    5. Part III. Latent Autoimmune Diabetes in Adults
    6. Part IV. Animal Models
    7. Part V. T Cells
    8. Part VI. Autoantibodies
    9. Part VII. Genetics
    10. Part VIII. Prediction and Prevention
    11. Index of Contributors
    1. TSH Receptor Antibodies in Subjects with Type 1 Diabetes Mellitus (pages 220–225)

      AMBIKA G. UNNIKRISHNAN, VELAYUTHAM KUMARAVEL, VASANTHA NAIR, ANANTH RAO, ROHINI V. JAYAKUMAR, HARISH KUMAR and CARANI B. SANJEEVI

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.034

    2. Time-Resolved Fluorescence Imaging of Islet Cell Autoantibodies (pages 226–228)

      PAULI VUORINEN, MARIS RULLI, ARI KUUSISTO, SATU SIMELL, TUULA SIMELL, TERO VAHLBERG, JORMA ILONEN, HEIKKI HYÖTY, MIKAEL KNIP and OLLI SIMELL

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.035

    3. MHC Class I Chain-Related Gene-A Is Associated with IA2 and IAA but Not GAD in Swedish Type 1 Diabetes Mellitus (pages 229–239)

      MANU GUPTA, JINKO GRAHAM, BRIAN McNEENY, MARIAN ZARGHAMI, MONA LANDIN-OLSSON, WILLIAM A. HAGOPIAN, JERRY PALMER, ÅKE LERNMARK and CARANI B. SANJEEVI

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.036

  8. Part VII. Genetics

    1. Top of page
    2. Overview
    3. Part I. Special Papers
    4. Part II. Diabetes in Asia
    5. Part III. Latent Autoimmune Diabetes in Adults
    6. Part IV. Animal Models
    7. Part V. T Cells
    8. Part VI. Autoantibodies
    9. Part VII. Genetics
    10. Part VIII. Prediction and Prevention
    11. Index of Contributors
    1. Predominance of the Group A Killer Ig-Like Receptor Haplotypes in Korean Patients With T1D (pages 240–250)

      YONGSOO PARK, HEEJIN CHOI, HYEWON PARK, SUKYUNG PARK, EUN-KYUNG YOO, DUKHEE KIM and CARANI B. SANJEEVI

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.037

    2. Frequency of CTLA-4 Gene CT60 Polymorphism May Not Be Affected by Vitamin D Receptor Gene Bsm I Polymorphism or HLA DR9 in Autoimmune-Related Type 1 Diabetes in the Japanese (pages 251–256)

      YASUHIKO KANAZAWA, YOSHIKO MOTOHASHI, SATORU YAMADA, YOICHI OIKAWA, TOSHIKATSU SHIGIHARA, YOSHIAKI OKUBO, TARO MARUYAMA and AKIRA SHIMADA

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.038

    3. No Association of TLR2 and TLR4 Polymorphisms with Type I Diabetes Mellitus in the Basque Population (pages 268–272)

      IZORTZE SANTIN, JOSE RAMON BILBAO, GUIOMAR PÉREZ DE NANCLARES, BEGOÑA CALVO and LUIS CASTAÑO

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.040

    4. Association of SUMO4 M55V Polymorphism with Autoimmune Diabetes in Latvian Patients (pages 273–277)

      SAIKIRAN K. SEDIMBI, ARUN SHASTRY, YONGSOO PARK, INGRIDA RUMBA and CARANI B. SANJEEVI

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.041

    5. A Second Component of HLA-Linked Susceptibility to Type 1 Diabetes Maps to Class I Region (pages 278–284)

      YUMIKO KAWABATA, HIROSHI IKEGAMI, TOMOMI FUJISAWA, SHINSUKE NOSO, KATSUAKI ASANO, YOSHIHISA HIROMINE and TOSHIO OGIHARA

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.042

    6. Molecular Scanning of the Gene for Programmed Cell Death-1 (PDCD-1) as a Candidate for Type 1 Diabetes Susceptibility (pages 285–288)

      YOSHIHISA HIROMINE, HIROSHI IKEGAMI, TOMOMI FUJISAWA, YUMIKO KAWABATA, SHINSUKE NOSO, KAORI YAMAJI, KATSUAKI ASANO and TOSHIO OGIHARA

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.043

    7. Genetic Determinants of Type 1 Diabetes Across Populations (pages 289–299)

      MOHAMED M. JAHROMI and GEORGE S. EISENBARTH

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.044

    8. TNFa-e Microsatellite, HLA-DRB1 and -DQB1 Alleles and Haplotypes in Brazilian Patients Presenting Recently Diagnosed Type 1 Diabetes Mellitus (pages 300–304)

      DIANE M. RASSI, ISABELA J. WASTOWSKI, RENATA T. SIMÕES, SANDRA RODRIGUES, NEIFE N.H.S. DEGHAIDE, CELSO T. MENDES-JUNIOR, AGUINALDO L. SIMÕES, C.P. SOARES, GERALDO A.S. PASSOS and EDUARDO A. DONADI

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.045

    9. Is HLA Class II Profile Relevant for the Study of Large-Scale Differentially Expressed Genes in Type 1 Diabetes Mellitus Patients? (pages 305–309)

      DIANE M. RASSI, CRISTINA M. JUNTA, ANA L. FACHIN, PAULA SANDRIN-GARCIA, STEPHANO S. MELLO, ANA P.M. FERNANDES, NEIFE N.H.S. DEGHAIDE, MARIA C. FOSS-FREITAS, MILTON C. FOSS, ELZA T. SAKAMOTO-HOJO, GERALDO A.S. PASSOS and EDUARDO A. DONADI

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.046

  9. Part VIII. Prediction and Prevention

    1. Top of page
    2. Overview
    3. Part I. Special Papers
    4. Part II. Diabetes in Asia
    5. Part III. Latent Autoimmune Diabetes in Adults
    6. Part IV. Animal Models
    7. Part V. T Cells
    8. Part VI. Autoantibodies
    9. Part VII. Genetics
    10. Part VIII. Prediction and Prevention
    11. Index of Contributors
    1. Interleukin-10 Plasmid Construction and Delivery for the Prevention of Type 1 Diabetes (pages 313–319)

      MINHYUNG LEE, HYEWON PARK, JEEHEE YOUN, EUN TAEX OH, KYUNGSOO KO, SUNGWAN KIM and YONGSOO PARK

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.048

    2. TEDDY–The Environmental Determinants of Diabetes in the Young : An Observational Clinical Trial (pages 320–326)

      WILLIAM A. HAGOPIAN, ÅKE LERNMARK, MARIAN J. REWERS, OLLI G. SIMELL, JIN-XIONG SHE, ANETTE G. ZIEGLER, JEFFREY P. KRISCHER and BEENA AKOLKAR

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.049

    3. Protection From Type 1 Diabetes by Vitamin D Receptor Haplotypes (pages 327–334)

      ELIZABETH RAMOS-LOPEZ, THOMAS JANSEN, VYTAUTAS IVASKEVICIUS, HEINRICH KAHLES, CHRISTIAN KLEPZIG, JOHANNES OLDENBURG and KLAUS BADENHOOP

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.050

    4. Living Donor Islet Transplantation, the Alternative Approach to Overcome the Obstacles Limiting Transplant (pages 335–339)

      YASUHIRO IWANAGA, SHINICHI MATSUMOTO, TERU OKITSU, HIROFUMI NOGUCHI, HIDEO NAGATA, YUKIHIDE YONEKAWA, YUICHIRO YAMADA, KAZUHITO FUKUDA, KATSUSHI TSUKIYAMA and KOICHI TANAKA

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.051

    5. Cord Blood Islet Autoantibodies Are Related to Stress in the Mother during Pregnancy (pages 345–349)

      BARBRO LERNMARK, KRISTIAN LYNCH, Å KE LERNMARK and THE DiPiS STUDY GROUP

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.053

    6. Thiazolidinediones May Not Reduce Diabetes Incidence in Type 1 Diabetes (pages 365–368)

      TOSHIKATSU SHIGIHARA, YOSHIAKI OKUBO, YASUHIKO KANAZAWA, YOICHI OIKAWA and AKIRA SHIMADA

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.056

    7. Mechanisms Mediating Anti-CD3 Antibody Efficacy : Insights from a Mathematical Model of Type 1 Diabetes (pages 369–373)

      DANIEL L. YOUNG, SAROJA RAMANUJAN, HUUB T.C. KREUWEL, CHAN CHUNG WHITING, KAPIL G. GADKAR and LISL K.M. SHODA

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.057

    8. Overcoming the Challenges Now Limiting Islet Transplantation : A Sequential, Integrated Approach (pages 383–398)

      ANTONELLO PILEGGI, LORENZO COBIANCHI, LUCA INVERARDI and CAMILLO RICORDI

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.059

  10. Index of Contributors

    1. Top of page
    2. Overview
    3. Part I. Special Papers
    4. Part II. Diabetes in Asia
    5. Part III. Latent Autoimmune Diabetes in Adults
    6. Part IV. Animal Models
    7. Part V. T Cells
    8. Part VI. Autoantibodies
    9. Part VII. Genetics
    10. Part VIII. Prediction and Prevention
    11. Index of Contributors
    1. Index of Contributors (pages 399–401)

      Article first published online: 9 NOV 2006 | DOI: 10.1196/annals.1375.1402

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