Annals of the New York Academy of Sciences

Cover image for Vol. 1089 Estrogens and Human Diseases

November 2006

Volume 1089 Estrogens and Human Diseases

Pages xiii–xxiii, 1–551

  1. PREFACE

    1. Top of page
    2. PREFACE
    3. Inside Cancer Complexity
    4. In Tribute to Luigi Castagnetta—Drawings
    5. Part I. Estrogens, Development, and Cancer
    6. Part II. New Insights into Estrogen Action
    7. Part III. Estrogens and Cancer I—Breast Cancer
    8. Part IV. Estrogen and Cancer II—Prostate Cancer
    9. Part V. Estrogen and Cancer III—Liver Cancer
    10. Part VI. Estrogens and Neurodegenerative Disorders
    11. Minisymposium
    12. Part VII. Estrogens and Cardiovascular Diseases
    13. Part VIII. Estrogens and Immune Diseases
    14. Index of Contributors
    1. Preface (pages xiii–xiv)

      H. Leon Bradlow and Giuseppe Carruba

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.038

  2. Inside Cancer Complexity

    1. Top of page
    2. PREFACE
    3. Inside Cancer Complexity
    4. In Tribute to Luigi Castagnetta—Drawings
    5. Part I. Estrogens, Development, and Cancer
    6. Part II. New Insights into Estrogen Action
    7. Part III. Estrogens and Cancer I—Breast Cancer
    8. Part IV. Estrogen and Cancer II—Prostate Cancer
    9. Part V. Estrogen and Cancer III—Liver Cancer
    10. Part VI. Estrogens and Neurodegenerative Disorders
    11. Minisymposium
    12. Part VII. Estrogens and Cardiovascular Diseases
    13. Part VIII. Estrogens and Immune Diseases
    14. Index of Contributors
    1. Inside Cancer Complexity (page xv)

      Luisa M. Massimo

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.019

  3. In Tribute to Luigi Castagnetta—Drawings

    1. Top of page
    2. PREFACE
    3. Inside Cancer Complexity
    4. In Tribute to Luigi Castagnetta—Drawings
    5. Part I. Estrogens, Development, and Cancer
    6. Part II. New Insights into Estrogen Action
    7. Part III. Estrogens and Cancer I—Breast Cancer
    8. Part IV. Estrogen and Cancer II—Prostate Cancer
    9. Part V. Estrogen and Cancer III—Liver Cancer
    10. Part VI. Estrogens and Neurodegenerative Disorders
    11. Minisymposium
    12. Part VII. Estrogens and Cardiovascular Diseases
    13. Part VIII. Estrogens and Immune Diseases
    14. Index of Contributors
  4. Part I. Estrogens, Development, and Cancer

    1. Top of page
    2. PREFACE
    3. Inside Cancer Complexity
    4. In Tribute to Luigi Castagnetta—Drawings
    5. Part I. Estrogens, Development, and Cancer
    6. Part II. New Insights into Estrogen Action
    7. Part III. Estrogens and Cancer I—Breast Cancer
    8. Part IV. Estrogen and Cancer II—Prostate Cancer
    9. Part V. Estrogen and Cancer III—Liver Cancer
    10. Part VI. Estrogens and Neurodegenerative Disorders
    11. Minisymposium
    12. Part VII. Estrogens and Cardiovascular Diseases
    13. Part VIII. Estrogens and Immune Diseases
    14. Index of Contributors
  5. Part II. New Insights into Estrogen Action

    1. Top of page
    2. PREFACE
    3. Inside Cancer Complexity
    4. In Tribute to Luigi Castagnetta—Drawings
    5. Part I. Estrogens, Development, and Cancer
    6. Part II. New Insights into Estrogen Action
    7. Part III. Estrogens and Cancer I—Breast Cancer
    8. Part IV. Estrogen and Cancer II—Prostate Cancer
    9. Part V. Estrogen and Cancer III—Liver Cancer
    10. Part VI. Estrogens and Neurodegenerative Disorders
    11. Minisymposium
    12. Part VII. Estrogens and Cardiovascular Diseases
    13. Part VIII. Estrogens and Immune Diseases
    14. Index of Contributors
    1. Epigenetics and the Estrogen Receptor (pages 73–87)

      JENNIFER E. LEADER, CHENGUANG WANG, VLADIMIR M. POPOV, MAOFU FU and RICHARD G. PESTELL

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.047

    2. Red Wine Extract Prevents Neuronal Apoptosis in Vitro and Reduces Mortality of Transgenic Mice (pages 88–97)

      ROSALBA AMODIO, ENNIO ESPOSITO, CATERINA DE RUVO, VINCENZO BELLAVIA, EMANUELE AMODIO and GIUSEPPE CARRUBA

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.026

    3. Regulatory Cytokine Gene Polymorphisms and Risk of Colorectal Carcinoma (pages 98–103)

      ANTONINO CRIVELLO, ANTONIO GIACALONE, MARINA VAGLICA, LETIZIA SCOLA, GIUSI IRMA FORTE, MARIA CATENA MACALUSO, CRISTINA RAIMONDI, LAURA DI NOTO, ALBERTO BONGIOVANNI, ANGELA ACCARDO, GIUSEPPINA CANDORE, LAURA PALMERI, ROBERTO VERNA, CALOGERO CARUSO, DOMENICO LIO and SERGIO PALMERI

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.002

    4. Cytokine Gene Polymorphisms and Breast Cancer Susceptibility (pages 104–109)

      LETIZIA SCOLA, MARINA VAGLICA, ANTONINO CRIVELLO, LAURA PALMERI, GIUSI IRMA FORTE, MARIA CATENA MACALUSO, ANTONIO GIACALONE, LAURA DI NOTO, ALBERTO BONGIOVANNI, CRISTINA RAIMONDI, ANGELA ACCARDO, ROBERTO VERNA, GIUSEPPINA CANDORE, CALOGERO CARUSO, DOMENICO LIO and SERGIO PALMERI

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.017

  6. Part III. Estrogens and Cancer I—Breast Cancer

    1. Top of page
    2. PREFACE
    3. Inside Cancer Complexity
    4. In Tribute to Luigi Castagnetta—Drawings
    5. Part I. Estrogens, Development, and Cancer
    6. Part II. New Insights into Estrogen Action
    7. Part III. Estrogens and Cancer I—Breast Cancer
    8. Part IV. Estrogen and Cancer II—Prostate Cancer
    9. Part V. Estrogen and Cancer III—Liver Cancer
    10. Part VI. Estrogens and Neurodegenerative Disorders
    11. Minisymposium
    12. Part VII. Estrogens and Cardiovascular Diseases
    13. Part VIII. Estrogens and Immune Diseases
    14. Index of Contributors
    1. Adjuvant Diet to Improve Hormonal and Metabolic Factors Affecting Breast Cancer Prognosis (pages 110–118)

      FRANCO BERRINO, ANNA VILLARINI, MICHELA DE PETRIS, MILENA RAIMONDI and PATRIZIA PASANISI

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.023

    2. TGF-Beta Signaling in Breast Cancer (pages 119–126)

      MIRIAM B. BUCK and CORNELIUS KNABBE

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.024

    3. Antihormones in Prevention and Treatment of Breast Cancer (pages 143–158)

      RICCARDO PONZONE, NICOLETTA BIGLIA, MARIA ELENA JACOMUZZI, LUCA MARIANI, ANNELISE DOMINGUEZ and PIERO SISMONDI

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.037

    4. HER2/neu Expression in Relation to Clinicopathologic Features of Breast Cancer Patients (pages 159–167)

      ADELE TRAINA, BIAGIO AGOSTARA, LORENZO MARASÀ, MAURIZIO CALABRÒ, MAURIZIO ZARCONE and GIUSEPPE CARRUBA

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.029

  7. Part IV. Estrogen and Cancer II—Prostate Cancer

    1. Top of page
    2. PREFACE
    3. Inside Cancer Complexity
    4. In Tribute to Luigi Castagnetta—Drawings
    5. Part I. Estrogens, Development, and Cancer
    6. Part II. New Insights into Estrogen Action
    7. Part III. Estrogens and Cancer I—Breast Cancer
    8. Part IV. Estrogen and Cancer II—Prostate Cancer
    9. Part V. Estrogen and Cancer III—Liver Cancer
    10. Part VI. Estrogens and Neurodegenerative Disorders
    11. Minisymposium
    12. Part VII. Estrogens and Cardiovascular Diseases
    13. Part VIII. Estrogens and Immune Diseases
    14. Index of Contributors
    1. Crosstalk between EGFR and Extranuclear Steroid Receptors (pages 194–200)

      ANTIMO MIGLIACCIO, GABRIELLA CASTORIA, MARINA DI DOMENICO, ALESSANDRA CIOCIOLA, MARIA LOMBARDI, ANTONIETTA DE FALCO, MERLIN NANAYAKKARA, DANIELA BOTTERO, ROSINA DE STASIO, LILIAN VARRICCHIO and FERDINANDO AURICCHIO

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.006

  8. Part V. Estrogen and Cancer III—Liver Cancer

    1. Top of page
    2. PREFACE
    3. Inside Cancer Complexity
    4. In Tribute to Luigi Castagnetta—Drawings
    5. Part I. Estrogens, Development, and Cancer
    6. Part II. New Insights into Estrogen Action
    7. Part III. Estrogens and Cancer I—Breast Cancer
    8. Part IV. Estrogen and Cancer II—Prostate Cancer
    9. Part V. Estrogen and Cancer III—Liver Cancer
    10. Part VI. Estrogens and Neurodegenerative Disorders
    11. Minisymposium
    12. Part VII. Estrogens and Cardiovascular Diseases
    13. Part VIII. Estrogens and Immune Diseases
    14. Index of Contributors
    1. Sex Hormones and Risk of Liver Tumor (pages 228–236)

      L. GIANNITRAPANI, M. SORESI, E. LA SPADA, M. CERVELLO, N. D'ALESSANDRO and G. MONTALTO

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.044

    2. Hormonal Treatment of Human Hepatocellular Carcinoma (pages 252–261)

      MASSIMO DI MAIO, ERMELINDA DE MAIO, ALESSANDRO MORABITO, ROBERTA D'ANIELLO, GIANFRANCO DE FEO, CIRO GALLO and FRANCESCO PERRONE

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.007

    3. Metabolic Profiles of Androgens in Malignant Human Liver Cell Lines (pages 262–267)

      ORAZIA M. GRANATA, LETIZIA COCCIADIFERRO, VITALE MICELI, LUCIA M. POLITO, ILDEGARDA CAMPISI and GIUSEPPE CARRUBA

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.028

    4. Significance of Autologous Interleukin-6 Production in the HA22T/VGH Cell Model of Hepatocellular Carcinoma (pages 268–275)

      MANUELA LABBOZZETTA, MONICA NOTARBARTOLO, PAOLA POMA, LYDIA GIANNITRAPANI, MELCHIORRE CERVELLO, GIUSEPPE MONTALTO and NATALE D'ALESSANDRO

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.014

    5. Anti-inflammatory and Neuroprotective Effect of a Phytoestrogen Compound on Rat Microglia (pages 276–281)

      F. MAROTTA, G.S. MAO, T. LIU, D.H. CHUI, A. LORENZETTI, Y. XIAO and P. MARANDOLA

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.033

  9. Part VI. Estrogens and Neurodegenerative Disorders

    1. Top of page
    2. PREFACE
    3. Inside Cancer Complexity
    4. In Tribute to Luigi Castagnetta—Drawings
    5. Part I. Estrogens, Development, and Cancer
    6. Part II. New Insights into Estrogen Action
    7. Part III. Estrogens and Cancer I—Breast Cancer
    8. Part IV. Estrogen and Cancer II—Prostate Cancer
    9. Part V. Estrogen and Cancer III—Liver Cancer
    10. Part VI. Estrogens and Neurodegenerative Disorders
    11. Minisymposium
    12. Part VII. Estrogens and Cardiovascular Diseases
    13. Part VIII. Estrogens and Immune Diseases
    14. Index of Contributors
    1. Estrogen Action in Neuroprotection and Brain Inflammation (pages 302–323)

      SILVIA POZZI, VALERIA BENEDUSI, ADRIANA MAGGI and ELISABETTA VEGETO

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.035

  10. Minisymposium

    1. Top of page
    2. PREFACE
    3. Inside Cancer Complexity
    4. In Tribute to Luigi Castagnetta—Drawings
    5. Part I. Estrogens, Development, and Cancer
    6. Part II. New Insights into Estrogen Action
    7. Part III. Estrogens and Cancer I—Breast Cancer
    8. Part IV. Estrogen and Cancer II—Prostate Cancer
    9. Part V. Estrogen and Cancer III—Liver Cancer
    10. Part VI. Estrogens and Neurodegenerative Disorders
    11. Minisymposium
    12. Part VII. Estrogens and Cardiovascular Diseases
    13. Part VIII. Estrogens and Immune Diseases
    14. Index of Contributors
    1. The Puzzle of Myelodysplastic Syndrome: Focusing on Immunophenotyping, Cytogenetics, and Molecular Genetics

      The Role of Flow Cytometric Immunophenotyping in Myelodysplastic Syndromes (pages 383–394)

      GUIDO PAGNUCCO, CATERINA GIAMBANCO and FRANCESCO GERVASI

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.031

    2. Clinical Relevance of Cytogenetics in Myelodysplastic Syndromes (pages 395–410)

      PAOLO BERNASCONI, MARINA BONI, PAOLA MARIA CAVIGLIANO, SILVIA CALATRONI, ILARIA GIARDINI, BARBARA ROCCA, RITA ZAPPATORE, IRENE DAMBRUOSO and MARILENA CARESANA

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.034

    3. Genetic Abnormalities as Targets for Molecular Therapies in Myelodysplastic Syndromes (pages 411–423)

      DANIELA CILLONI, EMANUELA MESSA, FRANCESCA MESSA, SONIA CARTURAN, ILARIA DEFILIPPI, FRANCESCA ARRUGA, VALENTINA ROSSO, RENATA CATALANO, ENRICO BRACCO, PAOLO NICOLI and GIUSEPPE SAGLIO

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.030

  11. Part VII. Estrogens and Cardiovascular Diseases

    1. Top of page
    2. PREFACE
    3. Inside Cancer Complexity
    4. In Tribute to Luigi Castagnetta—Drawings
    5. Part I. Estrogens, Development, and Cancer
    6. Part II. New Insights into Estrogen Action
    7. Part III. Estrogens and Cancer I—Breast Cancer
    8. Part IV. Estrogen and Cancer II—Prostate Cancer
    9. Part V. Estrogen and Cancer III—Liver Cancer
    10. Part VI. Estrogens and Neurodegenerative Disorders
    11. Minisymposium
    12. Part VII. Estrogens and Cardiovascular Diseases
    13. Part VIII. Estrogens and Immune Diseases
    14. Index of Contributors
    1. Rapid Estrogen Actions in the Cardiovascular System (pages 424–430)

      TOMMASO SIMONCINI, PAOLO MANNELLA and ANDREA RICCARDO GENAZZANI

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.001

    2. Association between the Polymorphism of CCR5 and Alzheimer's Disease : Results of a Study Performed on Male and Female Patients from Northern Italy (pages 454–461)

      CARMELA RITA BALISTRERI, MARIA PAOLA GRIMALDI, SONYA VASTO, FLORINDA LISTI, MARTINA CHIAPPELLI, FEDERICO LICASTRO, DOMENICO LIO, CALOGERO CARUSO and GIUSEPPINA CANDORE

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.012

    3. 7-Nitroindazole Protects Striatal Dopaminergic Neurons against MPP+-Induced Degeneration : An in Vivo Microdialysis Study (pages 462–471)

      VINCENZO DI MATTEO, ARCANGELO BENIGNO, MASSIMO PIERUCCI, DAVIDE ANTONIO GIULIANO, GIUSEPPE CRESCIMANNO, ENNIO ESPOSITO and GIUSEPPE DI GIOVANNI

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.015

    4. Age-Related Inflammatory Diseases : Role of Genetics and Gender in the Pathophysiology of Alzheimer's Disease (pages 472–486)

      GIUSEPPINA CANDORE, CARMELA R. BALISTRERI, MARIA P. GRIMALDI, SONYA VASTO, FLORINDA LISTÌ, MARTINA CHIAPPELLI, FEDERICO LICASTRO, DOMENICO LIO and CALOGERO CARUSO

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.008

    5. A Study of Serum Immunoglobulin Levels in Elderly Persons That Provides New Insights into B Cell Immunosenescence (pages 487–495)

      FLORINDA LISTÌ, GIUSEPPINA CANDORE, MARIA ASSUNTA MODICA, MARIANGELA RUSSO, GABRIELE DI LORENZO, MARIA ESPOSITO-PELLITTERI, GIUSEPPINA COLONNA-ROMANO, ALESSANDRA AQUINO, MATTEO BULATI, DOMENICO LIO, CLAUDIO FRANCESCHI and CALOGERO CARUSO

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.013

    6. Role of Proinflammatory Alleles in Longevity and Atherosclerosis : Results of Studies Performed on −1562C/T MMP-9 in Centenarians and Myocardial Infarction Patients from Sicily (pages 496–501)

      DOMENICO NUZZO, SONYA VASTO, CARMELA R. BALISTRERI, DANIELE DI-CARLO, FLORINDA LISTÌ, GREGORIO CAIMI, MARCO CARUSO, ENRICO HOFFMANN, EGLE INCALCATERRA, DOMENICO LIO, CALOGERO CARUSO and GIUSEPPINA CANDORE

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.048

  12. Part VIII. Estrogens and Immune Diseases

    1. Top of page
    2. PREFACE
    3. Inside Cancer Complexity
    4. In Tribute to Luigi Castagnetta—Drawings
    5. Part I. Estrogens, Development, and Cancer
    6. Part II. New Insights into Estrogen Action
    7. Part III. Estrogens and Cancer I—Breast Cancer
    8. Part IV. Estrogen and Cancer II—Prostate Cancer
    9. Part V. Estrogen and Cancer III—Liver Cancer
    10. Part VI. Estrogens and Neurodegenerative Disorders
    11. Minisymposium
    12. Part VII. Estrogens and Cardiovascular Diseases
    13. Part VIII. Estrogens and Immune Diseases
    14. Index of Contributors
    1. Association between Platelet Glycoprotein Ib-α and Myocardial Infarction : Results of a Pilot Study Performed in Male and Female Patients from Sicily (pages 502–508)

      GIUSEPPINA CANDORE, GIUSEPPINA PIAZZA, ANTONINO CRIVELLO, MARIA PAOLA GRIMALDI, VALENTINA ORLANDO, MARCO CARUSO, GREGORIO CAIMI, ENRICO HOFFMANN, EGLE INCALCATERRA, DOMENICO LIO and CALOGERO CARUSO

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.011

    2. Genetic Control of Immune Response in Carriers of Ancestral Haplotype 8.1 : The Study of Chemotaxis (pages 509–515)

      GIUSEPPINA CANDORE, CARMELA R. BALISTRERI, ANNA MARIA CAMPAGNA, ALFREDO COLOMBO, IRENE CUPPARI, DANIELE DI-CARLO, MARIA P. GRIMALDI, VALENTINA ORLANDO, GIUSEPPINA PIAZZA, SONYA VASTO, DOMENICO LIO and CALOGERO CARUSO

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.003

    3. Immunogenetics, Gender, and Longevity (pages 516–537)

      GIUSEPPINA CANDORE, CARMELA R. BALISTRERI, FLORINDA LISTÌ, MARIA P. GRIMALDI, SONYA VASTO, GIUSEPPINA COLONNA-ROMANO, CLAUDIO FRANCESCHI, DOMENICO LIO, GRAZIELLA CASELLI and CALOGERO CARUSO

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.051

    4. Estrogens and Autoimmune Diseases (pages 538–547)

      MAURIZIO CUTOLO, SILVIA CAPELLINO, ALBERTO SULLI, BRUNO SERIOLI, MARIA ELENA SECCHI, BARBARA VILLAGGIO and RAINER H. STRAUB

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.043

  13. Index of Contributors

    1. Top of page
    2. PREFACE
    3. Inside Cancer Complexity
    4. In Tribute to Luigi Castagnetta—Drawings
    5. Part I. Estrogens, Development, and Cancer
    6. Part II. New Insights into Estrogen Action
    7. Part III. Estrogens and Cancer I—Breast Cancer
    8. Part IV. Estrogen and Cancer II—Prostate Cancer
    9. Part V. Estrogen and Cancer III—Liver Cancer
    10. Part VI. Estrogens and Neurodegenerative Disorders
    11. Minisymposium
    12. Part VII. Estrogens and Cardiovascular Diseases
    13. Part VIII. Estrogens and Immune Diseases
    14. Index of Contributors
    1. Index of Contributors (pages 549–551)

      Version of Record online: 11 DEC 2006 | DOI: 10.1196/annals.1386.auindex_1

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