Annals of the New York Academy of Sciences

Cover image for Vol. 1155 Steroid Enzymes and Cancer

February 2009

Volume 1155 Steroid Enzymes and Cancer

Pages ix–x, 1–337

  1. Preface

    1. Top of page
    2. Preface
    3. Original Articles
    4. Keynote Lecture
    5. Part I. Hydroxysteroid Dehydrogenases
    6. Part II. Hydroxylases
    7. Part III. Sulfatase, Sulfotransferase, and Glucuronidase
    8. Part IV. Aromatase I
    9. Part V. Aromatase II
    10. Keynote Lecture
    11. Part VI. Poster Papers
    12. Index of Contributors
    1. Preface (pages ix–x)

      H. Leon Bradlow and Giuseppe Carruba

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.04559.x

  2. Original Articles

    1. Top of page
    2. Preface
    3. Original Articles
    4. Keynote Lecture
    5. Part I. Hydroxysteroid Dehydrogenases
    6. Part II. Hydroxylases
    7. Part III. Sulfatase, Sulfotransferase, and Glucuronidase
    8. Part IV. Aromatase I
    9. Part V. Aromatase II
    10. Keynote Lecture
    11. Part VI. Poster Papers
    12. Index of Contributors
    1. Translational Research in Hormone-Related Cancer (pages 1–3)

      Luisa M. Massimo and Gian Paolo Tonini

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03680.x

  3. Keynote Lecture

    1. Top of page
    2. Preface
    3. Original Articles
    4. Keynote Lecture
    5. Part I. Hydroxysteroid Dehydrogenases
    6. Part II. Hydroxylases
    7. Part III. Sulfatase, Sulfotransferase, and Glucuronidase
    8. Part IV. Aromatase I
    9. Part V. Aromatase II
    10. Keynote Lecture
    11. Part VI. Poster Papers
    12. Index of Contributors
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      Organization, Integration, and Assembly of Genetic and Epigenetic Regulatory Machinery in Nuclear Microenvironments : Implications for Biological Control in Cancer (pages 4–14)

      Gary S. Stein, Sayyed K. Zaidi, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, Martin Montecino, Daniel W. Young, Amjad Javed, Jitesh Pratap, Je-Yong Choi, Syed A. Ali, Sandhya Pande and Mohammad Q. Hassan

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.03697.x

  4. Part I. Hydroxysteroid Dehydrogenases

    1. Top of page
    2. Preface
    3. Original Articles
    4. Keynote Lecture
    5. Part I. Hydroxysteroid Dehydrogenases
    6. Part II. Hydroxylases
    7. Part III. Sulfatase, Sulfotransferase, and Glucuronidase
    8. Part IV. Aromatase I
    9. Part V. Aromatase II
    10. Keynote Lecture
    11. Part VI. Poster Papers
    12. Index of Contributors
    1. Perspectives in Understanding the Role of Human 17β-Hydroxysteroid Dehydrogenases in Health and Disease (pages 15–24)

      Marc Meier, Gabriele Möller and Jerzy Adamski

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.03702.x

    2. 17β-Hydroxysteroid Dehydrogenases in Human Breast Cancer (pages 25–32)

      Shuji Nagasaki, Yasuhiro Miki, Jun-ichi Akahira, Takashi Suzuki and Hironobu Sasano

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03682.x

    3. Steroid Hormone Transforming Aldo-Keto Reductases and Cancer (pages 33–42)

      Trevor M. Penning and Michael C. Byrns

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.03700.x

    4. 5α-Reductase Isozymes and Androgen Actions in the Prostate (pages 43–56)

      Yuan-Shan Zhu and Julianne L. Imperato-McGinley

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.04115.x

  5. Part II. Hydroxylases

    1. Top of page
    2. Preface
    3. Original Articles
    4. Keynote Lecture
    5. Part I. Hydroxysteroid Dehydrogenases
    6. Part II. Hydroxylases
    7. Part III. Sulfatase, Sulfotransferase, and Glucuronidase
    8. Part IV. Aromatase I
    9. Part V. Aromatase II
    10. Keynote Lecture
    11. Part VI. Poster Papers
    12. Index of Contributors
    1. Estrogen Hydroxylation—The Good and the Bad (pages 57–67)

      Daniel W. Sepkovic and H. Leon Bradlow

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03675.x

    2. Estrogen Metabolism and Breast Cancer : A Risk Model (pages 68–75)

      Fritz F. Parl, Sheila Dawling, Nady Roodi and Philip S. Crooke

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03676.x

  6. Part III. Sulfatase, Sulfotransferase, and Glucuronidase

    1. Top of page
    2. Preface
    3. Original Articles
    4. Keynote Lecture
    5. Part I. Hydroxysteroid Dehydrogenases
    6. Part II. Hydroxylases
    7. Part III. Sulfatase, Sulfotransferase, and Glucuronidase
    8. Part IV. Aromatase I
    9. Part V. Aromatase II
    10. Keynote Lecture
    11. Part VI. Poster Papers
    12. Index of Contributors
    1. New Developments in Intracrinology of Human Breast Cancer : Estrogen Sulfatase and Sulfotransferase (pages 76–79)

      Hironobu Sasano, Shuji Nagasaki, Yasuhiro Miki and Takashi Suzuki

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03683.x

    2. The Development of Steroid Sulfatase Inhibitors for Hormone-Dependent Cancer Therapy (pages 80–87)

      Joanna M. Day, Atul Purohit, Helena J. Tutill, Paul A. Foster, L. W. Lawrence Woo, Barry V. L. Potter and Michael J. Reed

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03677.x

    3. Estrogen Sulfotransferases in Breast and Endometrial Cancers (pages 88–98)

      Jorge Raul Pasqualini

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.04113.x

    4. Potential Role of UGT Pharmacogenetics in Cancer Treatment and Prevention : Focus on Tamoxifen (pages 99–111)

      Philip Lazarus, Andrea S. Blevins-Primeau, Yan Zheng and Dongxiao Sun

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.04114.x

  7. Part IV. Aromatase I

    1. Top of page
    2. Preface
    3. Original Articles
    4. Keynote Lecture
    5. Part I. Hydroxysteroid Dehydrogenases
    6. Part II. Hydroxylases
    7. Part III. Sulfatase, Sulfotransferase, and Glucuronidase
    8. Part IV. Aromatase I
    9. Part V. Aromatase II
    10. Keynote Lecture
    11. Part VI. Poster Papers
    12. Index of Contributors
    1. Molecular Characterization of Aromatase (pages 112–120)

      Yanyan Hong, Hongzhi Li, Yate-Ching Yuan and Shiuan Chen

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.03703.x

    2. Regulation of Aromatase Expression in Breast Cancer Tissue (pages 121–131)

      S.E. Bulun, Z. Lin, H. Zhao, M. Lu, S. Amin, S. Reierstad and D. Chen

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.03705.x

    3. Estrogen Mediation of Breast Tumor Formation Involves Estrogen Receptor-Dependent, as Well as Independent, Genotoxic Effects (pages 132–140)

      Richard Santen, Ercole Cavalieri, Eleanor Rogan, Jose Russo, Joseph Guttenplan, James Ingle and Wei Yue

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03685.x

  8. Part V. Aromatase II

    1. Top of page
    2. Preface
    3. Original Articles
    4. Keynote Lecture
    5. Part I. Hydroxysteroid Dehydrogenases
    6. Part II. Hydroxylases
    7. Part III. Sulfatase, Sulfotransferase, and Glucuronidase
    8. Part IV. Aromatase I
    9. Part V. Aromatase II
    10. Keynote Lecture
    11. Part VI. Poster Papers
    12. Index of Contributors
    1. Aromatase Inhibitors and Breast Cancer (pages 162–173)

      Luciana Furtado Macedo, Gauri Sabnis and Angela Brodie

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03689.x

    2. The Dual, Opposing Roles of Estrogen in the Prostate (pages 174–186)

      Stuart J. Ellem and Gail P. Risbridger

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.04360.x

    3. Targeting Aromatase and Estrogen Signaling in Human Non-Small Cell Lung Cancer (pages 194–205)

      Diana C. Márquez-Garbán, Hsiao-Wang Chen, Lee Goodglick, Michael C. Fishbein and Richard J. Pietras

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.04116.x

  9. Keynote Lecture

    1. Top of page
    2. Preface
    3. Original Articles
    4. Keynote Lecture
    5. Part I. Hydroxysteroid Dehydrogenases
    6. Part II. Hydroxylases
    7. Part III. Sulfatase, Sulfotransferase, and Glucuronidase
    8. Part IV. Aromatase I
    9. Part V. Aromatase II
    10. Keynote Lecture
    11. Part VI. Poster Papers
    12. Index of Contributors
    1. Inflammation and Liver Cancer : New Molecular Links (pages 206–221)

      C. Berasain, J. Castillo, M.J. Perugorria, M.U. Latasa, J. Prieto and M.A. Avila

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.03704.x

  10. Part VI. Poster Papers

    1. Top of page
    2. Preface
    3. Original Articles
    4. Keynote Lecture
    5. Part I. Hydroxysteroid Dehydrogenases
    6. Part II. Hydroxylases
    7. Part III. Sulfatase, Sulfotransferase, and Glucuronidase
    8. Part IV. Aromatase I
    9. Part V. Aromatase II
    10. Keynote Lecture
    11. Part VI. Poster Papers
    12. Index of Contributors
    1. Application of a New Classification to a Breast Tumor Series from a Population-Based Cancer Registry : Demographic, Clinical, and Prognostic Features of Incident Cases, Palermo Province, 2002–2004 (pages 222–226)

      Maurizio Zarcone, Rosalba Amodio, Ildegarda Campisi, Rosanna Cusimano, Cecilia Dolcemascolo, Vitale Miceli, Adele Traina and Maurizio Macaluso

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03693.x

    2. Endocrine Therapy in Metastatic Breast Cancer : Data from Breast Cancer Registry of Palermo, 1999–2005 (pages 227–231)

      Rosalba Amodio, Maurizio Zarcone, Biagio Agostara, Rosalba Staiti, Orazia Maria Granata, Giuseppe Carruba and Adele Traina

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03692.x

    3. Dietary Enterolactone Affects Androgen and Estrogen Levels in Healthy Postmenopausal Women (pages 232–236)

      Orazia M. Granata, Adele Traina, Stefania Ramirez, Ildegarda Campisi, Maurizio Zarcone, Rosalba Amodio, Lucia M. Polito and Giuseppe Carruba

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03690.x

    4. 16α-Hydroxyestrone Inhibits Estrogen Sulfotransferase Activity in Human Liver Cancer Cells (pages 237–241)

      Ildegarda Campisi, Orazia M. Granata, Letizia Cocciadiferro, Maurizio Calabrò, Lucia M. Polito and Giuseppe Carruba

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03694.x

    5. Clues to Understanding the Oxidation of Estradiol in Humans : Effects of Acute Infectious Hepatitis, Autoimmune Hepatitis, and Chronic Liver Disease (pages 242–251)

      Robert G. Lahita, Robert A. Schaefer, H. Leon Bradlow and Mary Jeanne Kreek

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.04359.x

    6. Aromatase and Amphiregulin Are Correspondingly Expressed in Human Liver Cancer Cells (pages 252–256)

      Vitale Miceli, Melchiorre Cervello, Antonina Azzolina, Giuseppe Montalto, Maurizio Calabrò and Giuseppe Carruba

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.03695.x

    7. Profiling Cancer Stem Cells in Androgen-Responsive and Refractory Human Prostate Tumor Cell Lines (pages 257–262)

      Letizia Cocciadiferro, Vitale Miceli, Kyung-Sun Kang, Lucia M. Polito, James E. Trosko and Giuseppe Carruba

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.03696.x

    8. Sex Steroids Upregulate the IGF-1R in Prostate Cancer Cells through a Nongenotropic Pathway (pages 263–267)

      Giuseppe Pandini, Marco Genua, Francesco Frasca, Riccardo Vigneri and Antonino Belfiore

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.04361.x

    9. Low Levels of Both Xanthine Dehydrogenase and Cellular Retinol Binding Protein Are Responsible for Retinoic Acid Deficiency in Malignant Human Mammary Epithelial Cells (pages 268–272)

      Gennaro Taibi, Giuseppe Carruba, Letizia Cocciadiferro, Orazia M. Granata and Concetta M.A. Nicotra

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03687.x

    10. Inhibition of Human Breast Cancer Cell Growth and Enzymatic Activity by a Fermented Nutraceutical : An in Vitro and in Vivo Study (pages 273–277)

      F. Marotta, H. Yadav, S. Pathak, E. Minelli, P. Signorelli, A. Lorenzetti and P. Marandola

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03684.x

    11. Curcumin as a Possible Lead Compound against Hormone-Independent, Multidrug-Resistant Breast Cancer (pages 278–283)

      Manuela Labbozzetta, Monica Notarbartolo, Paola Poma, Annamaria Maurici, Luigi Inguglia, Paolo Marchetti, Michele Rizzi, Riccardo Baruchello, Daniele Simoni and Natale D'Alessandro

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.03699.x

    12. Genetic Determined Downregulation of Both Type 1 and Type 2 Cytokine Pathways Might Be Protective against Pancreatic Cancer (pages 284–288)

      Letizia Scola, Antonio Giacalone, Lorenzo Marasà, Monica Mirabile, Loredana Vaccarino, Giusi Irma Forte, Lydia Giannitrapani, Calogero Caruso, Giuseppe Montalto and Domenico Lio

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03686.x

    13. CCR5 Proinflammatory Allele in Prostate Cancer Risk : A Pilot Study in Patients and Centenarians from Sicily (pages 289–292)

      Carmela Rita Balistreri, Giuseppe Carruba, Maurizio Calabrò, Ildegarda Campisi, Daniele Di Carlo, Domenico Lio, Giuseppina Colonna-Romano, Giuseppina Candore and Calogero Caruso

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03691.x

    14. Cyclooxygenase-2 Expression in Chronic Liver Diseases and Hepatocellular Carcinoma : An Immunohistochemical Study (pages 293–299)

      Lydia Giannitrapani, Sabrina Ingrao, Maurizio Soresi, Ada Maria Florena, Emanuele La Spada, Luigi Sandonato, Natale D'Alessandro, Melchiorre Cervello and Giuseppe Montalto

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.03698.x

    15. Prostaglandin E2 Receptors and COX Enzymes in Human Hepatocellular Carcinoma : Role in the Regulation of Cell Growth (pages 300–308)

      Antonella Cusimano, Daniela Foderà, Nadia Lampiasi, Antonina Azzolina, Monica Notarbartolo, Lydia Giannitrapani, Natale D'Alessandro, Giuseppe Montalto and Melchiorre Cervello

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.03701.x

    16. Involvement of Nitric Oxide in Nigrostriatal Dopaminergic System Degeneration : A Neurochemical Study (pages 309–315)

      Vincenzo Di Matteo, Massimo Pierucci, Arcangelo Benigno, Giuseppe Crescimanno, Ennio Esposito and Giuseppe Di Giovanni

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03678.x

    17. The Unilateral Nigral Lesion Induces Dramatic Bilateral Modification on Rat Brain Monoamine Neurochemistry (pages 316–323)

      Massimo Pierucci, Vincenzo Di Matteo, Arcangelo Benigno, Giuseppe Crescimanno, Ennio Esposito and Giuseppe Di Giovanni

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03679.x

    18. Parkinson's Disease and Cancer : Insights for Pathogenesis from Epidemiology (pages 324–334)

      Marco D'Amelio, Paolo Ragonese, Gabriella Sconzo, Paolo Aridon and Giovanni Savettieri

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2008.03681.x

  11. Index of Contributors

    1. Top of page
    2. Preface
    3. Original Articles
    4. Keynote Lecture
    5. Part I. Hydroxysteroid Dehydrogenases
    6. Part II. Hydroxylases
    7. Part III. Sulfatase, Sulfotransferase, and Glucuronidase
    8. Part IV. Aromatase I
    9. Part V. Aromatase II
    10. Keynote Lecture
    11. Part VI. Poster Papers
    12. Index of Contributors
    1. Index of Contributors (pages 335–337)

      Version of Record online: 26 FEB 2009 | DOI: 10.1111/j.1749-6632.2009.04560.x

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