Annals of the New York Academy of Sciences

Cover image for Vol. 1291 Pharmaceutical Science to Improve the Human Condition

July 2013

Volume 1291 Pharmaceutical Science to Improve the Human Condition

Pages 1–105

  1. Original Articles

    1. Top of page
    2. Original Articles
    1. You have full text access to this OnlineOpen article
      Development of ipilimumab: a novel immunotherapeutic approach for the treatment of advanced melanoma (pages 1–13)

      Jedd D. Wolchok, F. Stephen Hodi, Jeffrey S. Weber, James P. Allison, Walter J. Urba, Caroline Robert, Steven J. O'Day, Axel Hoos, Rachel Humphrey, David M. Berman, Nils Lonberg and Alan J. Korman

      Article first published online: 17 JUN 2013 | DOI: 10.1111/nyas.12180

    2. Development of everolimus, a novel oral mTOR inhibitor, across a spectrum of diseases (pages 14–32)

      David Lebwohl, Özlem Anak, Tarek Sahmoud, Judith Klimovsky, Ingrid Elmroth, Tomas Haas, Joseph Posluszny, Stephen Saletan and William Berg

      Article first published online: 9 MAY 2013 | DOI: 10.1111/nyas.12122

    3. Rivaroxaban: a novel oral anticoagulant for the prevention and treatment of several thrombosis-mediated conditions (pages 42–55)

      Troy C. Sarich, Gary Peters, Scott D. Berkowitz, Frank Misselwitz, Christopher C. Nessel, Paul Burton, Nancy Cook-Bruns, Anthonie W.A. Lensing, Lloyd Haskell, Elisabeth Perzborn, Dagmar Kubitza, Kenneth T. Moore, Sanjay Jalota, Juergen Weber, Guohua Pan, Xiang Sun, Torsten Westermeier, Andrea Nadel, Leonard Oppenheimer and Peter M. DiBattiste

      Article first published online: 23 MAY 2013 | DOI: 10.1111/nyas.12136

    4. You have full text access to this OnlineOpen article
      Development of lacosamide for the treatment of partial-onset seizures (pages 56–68)

      Pamela Doty, David Hebert, Francois-Xavier Mathy, William Byrnes, James Zackheim and Kelly Simontacchi

      Article first published online: 16 JUL 2013 | DOI: 10.1111/nyas.12213

    5. Development of boceprevir: a first-in-class direct antiviral treatment for chronic hepatitis C infection (pages 69–76)

      Daria J. Hazuda, Margaret Burroughs, Anita Y.M. Howe, Janice Wahl and Srikanth Venkatraman

      Article first published online: 16 JUL 2013 | DOI: 10.1111/nyas.12218

    6. You have full text access to this OnlineOpen article
    7. Tumor treating fields: a new frontier in cancer therapy (pages 86–95)

      Angela M. Davies, Uri Weinberg and Yoram Palti

      Article first published online: 9 MAY 2013 | DOI: 10.1111/nyas.12112

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