Multicenter Study

Factors Associated with Improvement in Utilization of Cardiac Resynchronization Therapy in Eligible Heart Failure Patients: Findings from IMPROVE HF

  1. ASHISH SHUKLA M.D., M.P.H.1,
  2. ANNE B. CURTIS M.D.1,
  3. MANDEEP R. MEHRA M.B.B.S.2,
  4. NANCY M. ALBERT Ph.D., R.N.3,
  5. MIHAI GHEORGHIADE M.D.4,
  6. J. THOMAS HEYWOOD M.D.5,
  7. YANG LIU M.S.6,
  8. CHRISTOPHER M. O'CONNOR M.D.7,
  9. DWIGHT REYNOLDS M.D.8,
  10. MARY NORINE WALSH M.D.9,
  11. CLYDE W. YANCY M.D.4,
  12. GREGG C. FONAROW M.D.10,*

Article first published online: 4 FEB 2013

DOI: 10.1111/pace.12090

Issue

Pacing and Clinical Electrophysiology

Pacing and Clinical Electrophysiology

Volume 36, Issue 4, pages 433–443, April 2013

Additional Information

How to Cite

SHUKLA, A., CURTIS, A. B., MEHRA, M. R., ALBERT, N. M., GHEORGHIADE, M., HEYWOOD, J. T., LIU, Y., O'CONNOR, C. M., REYNOLDS, D., WALSH, M. N., YANCY, C. W. and FONAROW, G. C. (2013), Factors Associated with Improvement in Utilization of Cardiac Resynchronization Therapy in Eligible Heart Failure Patients: Findings from IMPROVE HF. Pacing and Clinical Electrophysiology, 36: 433–443. doi: 10.1111/pace.12090

Author Information

  1. 1

    University at Buffalo, Buffalo, New York

  2. 2

    Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts

  3. 3

    Cleveland Clinic Foundation, Cleveland, Ohio

  4. 4

    Northwestern University Feinberg School of Medicine, Chicago, Illinois

  5. 5

    Scripps Clinic, La Jolla, California

  6. 6

    Medtronic, Inc., Mounds View, Minnesota

  7. 7

    Duke University Medical Center, Durham, North Carolina

  8. 8

    University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

  9. 9

    St Vincent Heart Center of Indiana, Indianapolis, Indiana

  10. 10

    Ronald Reagan UCLA Medical Center, Los Angeles, California

*Address for reprints: Gregg C. Fonarow, M.D., Ahmanson–UCLA Cardiomyopathy Center, Ronald Reagan UCLA Medical Center, 10833 LeConte Avenue, Room A2-237 CHS, Los Angeles, CA, 90095-1679. Fax: 310-206-9111; e-mail: gfonarow@mednet.ucla.edu

  1. Clinical trial registration information—URL: http://www. clinicaltrials.gov. Unique identifier: NCT00303979.

  2. Financial Support for the study: The IMPROVE HF registry and this study are supported by Medtronic, Inc., Minneapolis, Minnesota.

  3. Anne B. Curtis: Research grants: Medtronic (modest), honoraria: Medtronic (modest), consultant: Medtronic (modest), advisory board: Sanofi-Aventis (modest), St. Jude Medical (modest), Biosense Webster (modest); Janssen Pharmaceuticals (modest); Bristol-Myers-Squibb (modest).

  4. Mandeep R. Mehra: Consultant: Medtronic (modest), Johnson & Johnson (modest), St. Jude Medical (modest); Grants/research support: National Institutes of Health/NHLBI (significant), American Board of Internal Medicine (modest).

  5. Nancy Albert: honoraria: Medtronic (modest).

  6. Mihai Gheorghiade, Consultant: Abbott Laboratories (modest), Astellas (modest), Astra Zeneca (modest), Bayer Schering Pharma AG (significant), CorThera, Inc (modest), Cytokinetics, Inc (modest), DebioPharm SA (significant), Errekappa Terapeutici (Milan, Italy) (modest), GlaxoSmithKline (modest), Johnson & Johnson (modest), Medtronic (significant), Merck (modest), Novartis Pharma AG (significant), Otsuka Pharmaceuticals (significant), Pericor Therapeutics (significant), Protein Design Laboratories (modest), Sanofi-Aventis (modest), Sigma Tau (significant), Solvay Pharmaceuticals (significant).

  7. J. Thomas Heywood, Research grants: Biosite (modest), Medtronic (significant), St.Jude (significant); Speakers Bureau/honoraria:GlaxoSmithKline (modest), Medtronic (significant), AstraZeneca (modest), Novartis (modest); Actelion (significant), St. Jude (modest), Otsuka (modest), Boston Scientific (modest); Consultant/advisory board: Emerge (modest), Medtronic (significant), Actelion (modest).

  8. Yang Liu: Employee of Medtronic, Inc.

  9. Christopher M. O'Connor, Consultant: Forest (significant), Medtronic (significant), Amgen (significant), Medpace (significant), Impulse Dynamics (significant), Actelion (significant), Cytokinetics (modest), Roche (modest), Trevena (modest).

  10. Dwight Reynolds: Research grants: Medtronic, Biotronik; Speakers Bureau: Medtronic, Sorin; Consultant: Medtronic (all significant).

  11. Mary Norine Walsh: Consultant: United HealthCare (modest).

  12. Gregg C. Fonarow, Research grants: National Institutes of Health (significant); Consultant: Medtronic (modest), Novartis (significant); Honoraria: Medtronic (modest).

  13. Conflicts of Interest: Ashish Shukla and Clyde W. Yancy: No relationships to disclose.

Publication History

  1. Issue published online: 2 APR 2013
  2. Article first published online: 4 FEB 2013
  3. Manuscript Accepted: 24 NOV 2012
  4. Manuscript Revised: 27 OCT 2012
  5. Manuscript Received: 21 JUN 2012

Funded by

  • IMPROVE HF registry
  • Medtronic, Inc., Minneapolis, Minnesota

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