Both the authors have contributed equally.
Open-Irrigated Laser Catheter Ablation Produces Flow-Dependent Sizes of Lesions
Article first published online: 10 MAY 2013
©2013, The Authors. Journal compilation ©2013 Wiley Periodicals, Inc.
Pacing and Clinical Electrophysiology
Volume 36, Issue 9, pages 1132–1137, September 2013
How to Cite
WEBER, H. P. and SAGERER-GERHARDT, M. (2013), Open-Irrigated Laser Catheter Ablation Produces Flow-Dependent Sizes of Lesions. Pacing and Clinical Electrophysiology, 36: 1132–1137. doi: 10.1111/pace.12152
This study was supported in part by the LasCor GmbH – Laser Medical Devices, Taufkirchen, and by Omicron laserage, Rodgau, Germany.
Conflict of interest: HP Weber is CEO of the LasCor GmbH.
[Correction added after online publication 17-May 2013. Error in “Methods” section corrected.]
- Issue published online: 3 SEP 2013
- Article first published online: 10 MAY 2013
- Manuscript Accepted: 3 MAR 2013
- Manuscript Revised: 28 FEB 2013
- Manuscript Received: 12 FEB 2013
- LasCor GmbH – Laser Medical Devices, Taufkirchen
- Omicron laserage, Rodgau, Germany
- open-irrigated laser catheter;
- irrigation flow;
- energy settings;
- contact pressure
Growth and sizes of lesions produced during catheter ablation is difficult to control. Laser lesion formation was evaluated during various flow rates and energy settings by using an open-irrigated laser catheter on a thigh-muscle dog model.
Laser radiation at 15 W or 20 W was applied in blood for 10 seconds, 20 seconds, 30 seconds, 40 seconds, and 50 seconds during an irrigation flow of 16 mL/min or 35 mL/min, in direct contact, and in a noncontact mode of laser application. Lesions were evaluated morphometrically.
There was a linear increase of lesions with the increase of the level of energy applied. Maximal depth of lesions achieved during a flow rate of 16 mL/min at 15 W/50 seconds increased significantly from 9.9 ± 0.3 mm to 12.1 ± 0.5 mm, and at 20 W/50 seconds from 11.1 ± 0.55 mm to 12.4 ± 0.26 mm, when irrigation flow was 35 mL/min (P < 0.5). However, difference of lesion increase between 15 W and 20 W was not significant (P = 0.30). Lesions were achieved also in a noncontact mode of radiation at a distance of 1–2 mm, but not at 5 mm away. Radiation at 20 W > 40 seconds and a flow rate of 35 mL/min may cause steam pop with intramural cavitation.
By using an open-irrigated laser catheter augmentation of catheter flow increases lesion sizes. Lesions can be achieved also in a noncontact mode of radiation. In order to avoid unwanted effects the level of energy applied must be limited.