Authors Hongwu Chen and Bing Yang contributed equally to this work.
Long-Term Outcome Following Ablation of Atrial Tachycardias Occurring after Mitral Valve Replacement in Patients with Rheumatic Heart Disease
Article first published online: 6 JUN 2013
© 2013 The Authors. Pacing and Clinical Electrophysiology published by Wiley Periodicals, Inc.
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Pacing and Clinical Electrophysiology
Volume 36, Issue 7, pages 795–802, July 2013
How to Cite
CHEN, H., YANG, B., JU, W., ZHANG, F., GU, K., LI, M., WANG, J., CAO, K. and CHEN, M. (2013), Long-Term Outcome Following Ablation of Atrial Tachycardias Occurring after Mitral Valve Replacement in Patients with Rheumatic Heart Disease. Pacing and Clinical Electrophysiology, 36: 795–802. doi: 10.1111/pace.12153
This work was supported by the Program of Innovative Research Team in the First Affiliated Hospital of Nanjing Medical University (IRT-004).
Conflict of Interest: None.
- Issue published online: 1 JUL 2013
- Article first published online: 6 JUN 2013
- Manuscript Accepted: 21 MAR 2013
- Manuscript Revised: 25 FEB 2013
- Manuscript Received: 4 JAN 2013
- Innovative Research Team in the First Affiliated Hospital of Nanjing Medical University. Grant Number: IRT-004
- atrial tachycardia;
- atrial fibrillation;
- rheumatic heart disease;
- catheter ablation
Atrial tachycardia (AT) is a frequent late sequel of surgical valve replacement procedures in patients with rheumatic heart disease (RHD). The aim of this study was to evaluate the acute and long-term outcome of catheter ablation in such patients.
Methods and Results
A total of 21 consecutive RHD patients with AT after a valve replacement were enrolled in this study. The mean interval between the occurrence of symptomatic AT and the surgical intervention was 38.2 ± 48.7 months. The initial procedure was performed 8.4 ± 8.9 months after first onset of AT. During the first procedure, an electroanatomic mapping was completed for 25 ATs, 18 of which were cavotricuspid isthmus-dependent atrial flutter, five that were right atrial free wall AT, and two that were left AT. Acute success was obtained in 95% (20/21) patients. Nine patients with recurrent AT had repeat radiofrequency catheter ablation, and newly developed left AT was identified in five patients after the first right AT ablation. After a mean follow-up of 42.7 ± 17.3 months, only 33% of the patients remained free of ATs, while 14% and 53% of the patients had AT recurrence and the development of atrial fibrillation (AF), respectively.
Right but not left macroreentry is the most common AT postmitral valve replacement in patients with RHD. The incidence of AF is very high after AT ablation in such patients during the long-term follow-up.