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Validation of the Paediatric Food Allergy Quality of Life Questionnaire (PFA-QL)

Authors

  • Rebecca C. Knibb,

    Corresponding author
    • Department of Psychology, Faculty of Education Health and Sciences, University of Derby, Derby, UK
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  • Nur F. Ibrahim,

    1. Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK
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  • Rachel Petley,

    1. Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK
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  • Amanda J. Cummings,

    1. Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK
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  • Rosemary M. King,

    1. The Children's Allergy Clinic, University Hospital Southampton NHS Foundation Trust, Southampton, UK
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  • Graham Roberts,

    1. Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK
    2. NIHR Respiratory Biomedical Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK
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  • Michel Erlewyn-Lajeunesse,

    1. Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK
    2. The Children's Allergy Clinic, University Hospital Southampton NHS Foundation Trust, Southampton, UK
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  • Jane S. A. Lucas

    1. Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK
    2. NIHR Respiratory Biomedical Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK
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Correspondence

Rebecca Knibb, Department of Psychology, Faculty of Education Health and Sciences, University of Derby, Kedleston Road, Derby DE22 1GB, UK.

Tel.: 01332 593051

Fax: 01332 597747

E-mail: r.c.knibb@derby.ac.uk

Abstract

Background

The Paediatric Food Allergy Quality of Life Questionnaire (PFA-QL) was the first tool to be developed for assessing health-related quality of life (QoL) in children with food allergy. It has been used in a number of published studies, but has not been validated.

Objective

The aim of the current study was to validate child (PFA-QL) and parent–proxy (PFA-QL-PF) versions of the scale in a specialist allergy clinic and in parents of children with food allergy.

Methods

For the clinic sample, a generic QoL scale (PedsQL) and the PFA-QL were completed by 103 children (age 6–16 yrs) with peanut or tree nut allergy; test–retest reliability of the PFA-QL was tested in 50 stable patients. For the non-clinical sample, 756 parents of food allergic children completed the PFA-QL-PF, the Child Health Questionnaire (CHQ-PF50), Food Allergy Quality of Life Parental Burden Scale (FAQL-PB) and a Food Allergy Impact Measure.

Results

The PFA-QL and PFA-QL-PF had good internal consistency (α's of 0.77–0.82), and there was moderate-to-good agreement between the generic- and disease-specific questionnaires. The PFA-QL was stable over time in the clinic sample, and in both samples, girls were reported to have poorer QoL than boys.

Conclusions

The PFA-QL and PFA-QL-PF are reliable and valid scales for use in both clinical and non-clinical populations. Unlike other available tools, they were developed and validated in the UK and thus provide a culture-specific choice for research, clinical trials and clinical practice in the UK. Validation in other countries is now needed.

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