Educational Case Series
Managing a child with possible allergy to vaccine
Article first published online: 16 OCT 2013
© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Pediatric Allergy and Immunology
Volume 25, Issue 4, pages 394–403, June 2014
How to Cite
Managing a child with possible allergy to vaccine. Pediatr Allergy Immunol 2014: 25: 394–403., , , , , .
- Issue published online: 22 JUN 2014
- Article first published online: 16 OCT 2013
- Manuscript Accepted: 18 AUG 2013
Similarly to other medications, vaccines may be responsible for allergic reactions. Although IgE-mediated allergies to vaccine are extremely rare, they are clearly overdiagnosed. Indeed, accurate diagnosis of vaccine allergy is important not only to prevent serious or even life-threatening reactions, but also to avoid unnecessary vaccine restriction. Systematic approaches have been proposed and, if implemented, will likely reduce the number of children being inappropriately labeled as allergic to vaccine. In diagnosis of vaccine allergy, the patient's history is central although not sufficient. In case of suspicion of an allergy, the child should be referred to an allergist in order to perform a complete allergy workup, based primarily on skin tests and/or specific IgE. Highlighting the most recent literature, this article will address the management of children with a possible allergy to vaccine.