Food allergy and food-based therapies in neurodevelopmental disorders
Article first published online: 17 NOV 2013
© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Pediatric Allergy and Immunology
Volume 25, Issue 3, pages 218–226, May 2014
How to Cite
Food allergy and food-based therapies in neurodevelopmental disorders. Pediatr Allergy Immunol 2014: 25: 218–226., , , , , , .
- Issue published online: 21 APR 2014
- Article first published online: 17 NOV 2013
- Manuscript Accepted: 15 SEP 2013
- attention deficit hyperactivity disorder;
- autism spectrum disorder;
- food allergy;
- food-based therapy;
- gut-brain axis;
Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) are neurodevelopmental disorders which occur in childhood and may persist into adulthood. Although the etiology of these disorders is largely unknown, genetic and environmental factors are thought to play a role in the development of ASD and ADHD. Allergic immune reactions, in prenatal and postnatal phases, are examples of these environmental factors, and adverse reactions to foods are reported in these children. In this review, we address the clinical and preclinical findings of (food) allergy in ASD and ADHD and suggest possible underlying mechanisms. Furthermore, opportunities for nutritional interventions in neurodevelopmental disorders are provided.