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Figure S1 Some BTV8 structural proteins cause symptoms when expressed in plants individually, but not when expressed in combination with their structural neighbouring proteins.

Figure S2 Mass spectrometry analysis of 4 main protein bands recovered from SDS-PAGE analysis of a density gradient fractions from leaf tissue coinfiltrated with constructs for coexpression of BTV-8 VP2, VP3, VP5 and VP7.

Figure S3 Clarified extract from leaf tissue expression four BTV structural proteins, separated on two consecutive step sucrose gradients.

Figure S4 Densitometric analysis of Coomassie-stained gel of Figure 3b (inset).

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