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  • Akashi, T., Sawada, Y., Aoki, T. and Ayabe, S. (2000) New scheme of the biosynthesis of formononetin involving 2, 7, 4′-trihydroxyisoflavanone but not daidzein as the methyl acceptor. Biosci. Biotechnol. Biochem. 64, 22762279.
  • Akashi, T., Aoki, T. and Ayabe, S. (2005) Molecular and biochemical characterization of 2-hydroxyisoflavanone dehydratase. Involvement of carboxylesterase-like proteins in leguminous isoflavone biosynthesis. Plant Physiol. 137, 882891.
  • Birt, D.F., Hendrich, S. and Wang, W. (2001) Dietary agents in cancer prevention: flavonoids and isoflavonoids. Pharmacol. Ther. 90, 157177.
  • Botolin, S., Faugere, M.C., Malluche, H., Orth, M., Meyer, R. and McCabe, L.R. (2005) Increased bone adiposity and PPARγ2 expression in type I diabetic mice. Endocrinol. 146, 36223631.
  • Boyd, S.K., Davison, P., Muller, R. and Gasser, J.A. (2006) Monitoring individual morphological changes over time in Ovariectomized rats by in vivo micro-computed tomography. Bone, 39, 854862.
  • Butelli, E., Titta, L., Giorgio, M., Mock, H.P., Matros, A., Peterek, S., Schijlen, E.G., Hall, R.D., Bovy, A.G., Luo, J. and Martin, C. (2008) Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors. Nat. Biotechnol. 26, 13011308.
  • Cornwell, T., Cohick, W. and Raskin, I. (2004) Dietary phytoestrogens and health. Phytochem. 65, 9951016.
  • D'Amelio, P., Grimaldi, A., Di Bella, S., Tamone, C., Brianza, S.Z., Ravazzoli, M.G., Bernabei, P., Cristofaro, M.A., Pescarmona, G.P. and Isaia, G. (2008) Risedronate reduces osteoclast precursors and cytokine production in postmenopausal osteoporotic women. J. Bone Miner. Res. 23, 373379.
  • Dhaubhadel, S., Farhangkhoee, M. and Chapman, R. (2008) Identification and characterization of isoflavonoid specific glycosyltransferase and malonyltransferase from soybean seeds. J. Exp. Bot. 59, 981994.
  • Dixon, R.A. (1999) Isoflavonoids: biochemistry, molecular biology and biological functions. In Comprehensive Natural Products. Chemistry, Vol 1. (Sankawa, U. ed), pp 773823, Oxford, Elsevier.
  • Dixon, R.A. and Ferreira, D. (2002) Molecules of interest: genistein. Phytochem. 60, 205211.
  • Dixon, R.A. (2004) Phytoestrogens. Annu. Rev. Plant Biol. 55, 225261.
  • Farag, M., Huhman, D., Dixon, R. and Sumner, L. (2008) Metabolomics reveals novel pathways and differential mechanistic and elicitor-specific responses in phenylpropanoid and isoflavonoid biosynthesis in Medicago truncatula cell cultures. Plant Physiol. 146, 387402.
  • Grotewold, E. (2008) Transcription factors for predictive plant metabolic engineering: are we there yet? Curr. Opin. Biotechnol. 19, 138144.
  • Gupta, G.K., Kumar, A., Khedgikar, V., Kushwaha, P., Gautam, J., Nagar, G.K., Gupta, V., Verma, A., Dwivedi, A.K., Misra, A., Trivedi, R. and Mishra, P.R. (2013) Osteogenic efficacy enhancement of kaempferol through an engineered layer-by-layer matrix: a study in ovariectomized rats. Nanomedicine, 8, 757771.
  • Hichri, I., Barrieu, F., Bogs, J., Kappel, C., Delrot, S. and Lauvergeat, V. (2011) Recent advances in the transcriptional regulation of the flavonoid biosynthetic pathway. J. Exp. Bot. 62, 24652483.
  • Horcajada-Molteni, M.N., Crespy, V., Coxam, V., Davicco, M.J., Rémésy, C. and Barlet, J.P. (2000) Rutin inhibits ovariectomy-induced osteopenia in rats. J. Bone Miner. Res. 15, 22512258.
  • Horsch, R.B., Fry, J.E., Hoffmann, N.L., Eicholtz, D., Rogers, S.G. and Fraley, R.T. (1985) A simple method for transferring genes into plants. Science, 227, 12291231.
  • Iwasaki, M., Inoue, M., Otani, T., Sasazuki, S., Kurashi, N., Miura, T., Yamoto, S. and Tsugane, S. (2008) Plasma isoflavone level and subsequent risk of breast cancer among Japanese women: a nested case-control study from Japan Public Health Center-base prospective study group. J. Clin. Oncol. 26, 16771683.
  • Jorgensen, K., Rasmussen, A.V., Morant, M., Nielsen, A.H., Bjarnholt, N., Zagrobelny, M., Bak, S. and Møller, B.L. (2005) Metabolon formation and metabolic channeling in the biosynthesis of plant natural products. Curr. Opin. Plant Biol. 8, 280291.
  • Jung, W., Yu, O., Lau, S.-M.C., O'Keefe, D.P., Odell, J., Fader, G. and McGonigle, B. (2000) Identification and expression of isoflavone synthase, the key enzyme for biosynthesis of isoflavones in legumes. Nat. Biotech. 18, 208212.
  • Justesen, U., Knuthsen, P. and Leth, T. (1998) Quantitative analysis of flavonols, flavones, and flavanones in fruits, vegetables and beverages by highperformance liquid chromatography with photo diode array and mass spectrometric detection. J. Chromatogr. A. 799, 101110.
  • Khan, K., Singh, A., Mittal, M., Sharan, K., Singh, N., Dixit, P., Sanyal, S., Maurya, R. and Chattopadhyay, N. (2012) [6]-Gingerol induces bone loss in ovary intact adult mice and augments osteoclast function via the transient receptor potential vanilloid 1 channel. Mol. Nutr. Food Res. 56, 18601873.
  • Khedgikar, V., Kushwaha, P., Gautam, J., Verma, A., Changkija, B., Kumar, A., Sharma, S., Nagar, G., Singh, D., Trivedi, P.K., Sangwan, N.S., Mishra, P.K. and Trivedi, R. (2013) Withaferin A: a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone. Cell Death Dis. 4, e778.
  • Kumar, A., Singh, A.K., Gautam, A.K., Chandra, D., Singh, D., Changkija, B., Singh, M.P. and Trivedi, R. (2010) Identification of kaempferol-regulated proteins in rat calvarial osteoblasts during mineralization by proteomics. Proteomics. 10, 17301739.
  • Kumar, A., Gupta, G.K., Khedgikar, V., Gautam, J., Kushwaha, P., Changkija, B., Nagar, G.K., Gupta, V., Verma, A., Dwivedi, A.K., Chattopadhyay, N., Mishra, P.R. and Trivedi, R. (2012) In vivo efficacy studies of layer-by-layer nano-matrix bearing kaempferol for the conditions of osteoporosis: a study in ovariectomized rat model. J. Pharm. Biopharm. 82, 508517.
  • Lean, J.M., Davies, J.T., Fuller, K., Jagger, C.J., Kirstein, B., Partington, G.A., Urry, Z.L. and Chambers, T.J. (2003) A crucial role for thiol antioxidants in estrogen-deficiency bone loss. J Clin Invest. 112, 915923.
  • Lepiniec, L., Debeaujon, I., Routaboul, J.M., Baudry, A., Pourcel, L., Nesi, N. and Caboche, M. (2006) Genetics and biochemistry of seed flavonoids. Annu. Rev. Plant Biol. 57, 405430.
  • Liu, C.J., Blount, J.W., Steele, C.J. and Dixon, R.A. (2002) Bottlenecks for metabolic engineering of isoflavone glycoconjugates in Arabidopsis. Proc. Natl. Acad. Sci. USA, 99, 1457814583.
  • Liu, R., Hu, Y., Li, J. and Lin, Z. (2007) Production of soybean isoflavone genistein in non-legume plants via genetically modified secondary metabolism pathway. Metab. Eng. 9, 17.
  • Luo, J., Butelli, E., Hill, L., Parr, A., Niggeweg, R., Bailey, P., Weisshaar, B. and Martin, C. (2008) AtMYB12 regulates caffeoyl quinic acid and flavonol synthesis in tomato: expression in fruit results in very high levels of both types of polyphenols. Plant J. 56, 316326.
  • Miadokova, E. (2009) Isoflavonoids – an overview of their biological activities and potential health benefits. Interdisc. Toxicol. 2, 211218.
  • Miadokova, E., Masterova, I., Vlckova, V., Duhova, V. and Toth, J. (2002) Antimutagenic potential of homoisoflavonoids from Muscariracemosum. J. Ethnopharmacol. 18, 381386.
  • Misra, P., Pandey, A., Tewari, S.K., Nath, P. and Trivedi, P.K. (2010a) Characterization of isoflavone synthase gene from Psoralea corylifolia: a medicinal plant. Plant Cell Rep. 29, 747775.
  • Misra, P., Pandey, A., Tiwari, M., Chandrashekar, K., Sidhu, O.P., Asif, M.H., Chakrabarty, D., Singh, P.K., Trivedi, P.K., Nath, P. and Tuli, R. (2010b) Modulation of transcriptome and metabolome of tobacco by Arabidopsis transcription factor, AtMYB12, leads to insect resistance. Plant Physiol. 152, 22582268.
  • Niranjan, A., Pandey, A., Misra, P., Trivedi, P.K., Lehri, A. and Amla, D.V. (2011) Development and optimization of HPLC-PDA-MS-MS method for simultaneous quantification of three classes of flavonoids in legume seeds, vegetables, fruits and medicinal plants. J. Liq. Chromatogr. & Related Tech. 34, 17291742.
  • Occhiuto, F., Pasquale, R.D., Guglielmo, G., Palumbo, D.R., Zangla, G., Samperi, S., Renzo, A. and Circosta, C. (2007) Effects of phytoestrogenic isoflavones from red clover (Trifolium pratense L.) on experimental osteoporosis. Phytother Res. 21, 130134.
  • Ogo, Y., Ozawa, K., Ishimaru, T., Murayama, T. and Takaiwa, F. (2013) Transgenic rice seed synthesizing diverse flavonoids at high levels: a new platform for flavonoid production with associated health benefits. Plant Biotech. J. 11, 734746.
  • Pacifici, R. (1996) Estrogen, cytokines and pathogenesis of postmenopausal osteoporosis. J. Bone Miner. Res. 11, 10431051.
  • Pandey, R., Gautam, A.K., Bhargavan, B., Trivedi, R., Swarnkar, G., Nagar, G.K., Yadav, D.K., Kumar, M., Rawat, P., Manickavasagam, L., Kumar, A., Maurya, R., Goel, A., Jain, G.K., Chattopadhyay, N. and Singh, D. (2010) Total extract and standardized fraction from the stem bark of Buteamonosperma have osteoprotective action: evidence for the nonestrogenic osteogenic effect of the standardized fraction. Menopause, 17, 602610.
  • Pandey, A., Misra, P., Chandrashekhar, K. and Trivedi, P.K. (2012a) Development of AtMYB12-expressing transgenic tobacco callus culture for production of rutin with biopesticidal potential. Plant Cell Rep. 31, 18671876.
  • Pandey, A., Niranjan, A., Misra, P., Lehri, A., Tewari, S.K. and Trivedi, P.K. (2012b) Simultaneous separation and quantification of targeted group of compounds in Psoralea corylifolia L. using HPLC-PDA- MS-MS. J. Liq. Chromatogr. & Related Tech. 35, 25672583.
  • Peterson, G. and Barnes, S. (1991) Genistein inhibition of the growth of human breast cancer cells: independence from estrogen receptors and the multi-drug resistance gene. Biochem. Biophys. Res. Commun. 179, 661667.
  • Pie, J.E., Park, J.H., Park, Y.H., Ryu, Y.M., Kim, K.N., Suh, S.W., Becker, K.G., Cho-Chung, Y.S. and Kim, M.K. (2006) Effect of genistein on the expression of bone metabolism genes in ovariectomized mice using a cDNA microarray. J. Nutr. Biochem. 17, 157164.
  • Pueppke, S.G. (1996) The genetic and biochemical basis for nodulation of legumes by Rhizobia. Critical Rev. Biotech. 16, 151.
  • Ryan-Borchers, T.A., Park, J.S., Chew, B.P., McGuire, M.K., Fournier, L.R. and Beerman, K.A. (2006) Soy isoflavones modulate immune function in healthy postmenopausal women. Am. J. Clin. Nutr. 83, 1181125.
  • Samac, D.A. and Graham, M.A. (2007) Recent advances in legume-microbe interactions: recognition, defense response, and symbiosis from a genomic perspective. Plant Physiol. 144, 582587.
  • Scarpato, R., Paganucci, L., Bertoli, A., Fiore, L., Pistelli, L. and Federico, G. (2008) Licol avone C attenuates the genotoxicity of cancer drugs in human peripheral lymphocytes. Phytother. Res. 22, 16501654.
  • Sharan, K., Mishra, J.S., Swarnkar, G., Siddiqui, J.A., Khan, K., Kumari, R., Rawat, P., Maurya, R., Sanyal, S. and Chattopadhyay, N. (2011) A novel quercetin analogue from a medicinal plant promotes peak bone mass achievement and bone healing after injury and exerts an anabolic effect on osteoporotic bone: the role of aryl hydrocarbon receptor as a mediator of osteogenic action. J. Bone Miner. Res. 26, 2096.
  • Shih, C.H., Chen, Y., Wang, M., Chu, I.K. and Lo, C. (2008) Accumulation of isoflavone genistin in transgenic tomato plants overexpressing a soybean isoflavone synthase gene. J. Agric. Food Chem. 56, 56555661.
  • Shimamura, M., Akashi, T., Sakurai, N., Suzuki, H., Saito, K., Shibata, D., Ayabe, S. and Aoki, T. (2007) 2-Hydroxyisoflavanone dehydratase is a critical determinant of isoflavone productivity in hairy root cultures of Lotus japonicus. Plant Cell Physiol. 48, 16521657.
  • Siddiqui, J.A., Swarnkar, G., Sharan, K., Chakravarti, B., Sharma, G., Rawat, P., Kumar, M., Khan, F.M., Pierroz, D., Maurya, R. and Chattopadhyay, N. (2010) 8, 8“-Biapigeninyl stimulates osteoblast functions and inhibits osteoclast and adipocyte functions: osteoprotective action of 8, 8”-biapigeninyl in ovariectomized mice. Mol. Cell. Endocrinol. 323, 256267.
  • Srivastava, K., Khan, K., Tyagi, A.M., Khan, M.P., Yadav, D.K., Trivedi, R., Maurya, R., Singh, D. and Chattopadhyay, N. (2013a) Greater skeletal gains in ovary intact rats at maturity are achieved by supplementing a standardized extract of Butea monosperma stem-bark that confers better bone conserving effect following ovariectomy and concurrent treatment withdrawal. Evid. Based Complement. Alternat. Med. doi:10.1155/2013/519387.
  • Srivastava, K., Tyagi, A.M., Khan, K., Dixit, M., Lahiri, S., Kumar, A., Changkija, B., Khan, M.P., Nagar, G.K., Yadav, D.K., Maurya, R., Singh, S.P., Jain, G.K., Wahajuddin, Trivedi, R., Chattopadhyay, N. and Singh, D. (2013b) Isoformononetin, a methoxydaidzein present in medicinal plants, reverses bone loss in osteopenic rats and exerts bone anabolic action by preventing osteoblast apoptosis. Phytomedicine, 20, 470480.
  • Steele, C.L., Gijzen, M., Qutob, D. and Dixon, R.A. (1999) Molecular characterization of the enzyme catalyzing the aryl migration reaction of isoflavonoid biosynthesis in soybean. Arch. Biochem. Biophys. 367, 147150.
  • Suzuki, H., Nishino, T. and Nakayama, T. (2007) cDNA cloning of a BAHD acyltransferase from soybean (Glycine max): isoflavone 7-O-glucoside-6''-O-malonyltransferase. Phytochem. 68, 20352042.
  • Subramanian, S., Stacey, G. and Yu, O. (2007) Distinct, crucial roles of flavonoids during legume nodulation. Trend Plant Sci. 12, 282285.
  • Swarnkar, G., Sharan, K., Siddiqui, J.A., Mishra, J.S., Khan, K., Khan, M.P., Gupta, V., Rawat, P., Maurya, R., Dwivedi, A.K., Sanyal, S. and Chattopadhyay, N. (2011) A naturally occurring naringenin derivative exerts potent bone anabolic effects by mimicking oestrogen action on osteoblasts. Br. J. Pharmacol. 165, 15261542.
  • Tian, L. and Dixon, R.A. (2006) Engineering isoflavone metabolism with an artificial bifunctional enzyme. Planta. 224, 496507.
  • Trivedi, R., Kumar, S., Kumar, A., Siddiqui, J.A., Swarnkar, G., Gupta, V., Kendurker, A., Dwivedi, A.K., Romero, J.R. and Chattopadhyay, N. (2008) Kaempferol has osteogenic effect in ovariectomized adult Sprague-Dawley rats. Mol. Cell. Endocrinol. 289, 8593.
  • Trivedi, R., Kumar, A., Gupta, V., Kumar, S., Nagar, G.K., Romero, J.R., Dwivedi, A.K. and Chattopadhya, N. (2009) Effects of Egb 761 on bone mineral density, bone microstructure, and osteoblast function: possible roles of quercetin and kaempferol. Mol. Cell. Endocrinol. 302, 8691.
  • Tyagi, A.M., Gautam, A.K., Kumar, A., Srivastava, K., Bhargavan, B., Trivedi, R., Saravanam, S., Yadav, D.K., Singh, N., Pollet, C., Brazier, M., Mentaverri, R., Maurya, R., Chattopadhyay, N., Goel, A. and Chattopadhyay, N. (2010) Medicarpin inhibits osteoclastogenesis and has nonestrogenic bone conserving effect in ovariectomized mice. Mol. Cell. Endocrinol. 325, 101109.
  • Van Rhijn, P. and Vanderleyden, J. (1995) The Rhizobium-plant symbiosis. Microbiol. Rev. 59, 124142.
  • Veitch, N.C. (2007) Isoflavonoids of the leguminosae. Nat. Prod. Rep. 24, 417464.
  • Ververidis, F., Trantas, E., Douglas, C., Vollmer, G., Kretzschmar, G. and Panopoulos, N. (2007) Biotechnology of flavonoids and other phenylpropanoid-derived natural products, Part I: Chemical diversity, impacts on plant biology and human health. Biotechnol. J. 2, 12141234.
  • Wattel, A., Kamel, S., Mentaverri, R., Lorget, F., Prouillet, C., Petit, J.P., Fardelonne, P. and Brazier, M. (2003) Potent inhibitory effect of naturally occurring flavonoids quercetin and kaempferol on in vitro osteoclastic bone resorption. Biochem. Pharmacol. 65, 3542.
  • Wei, C., Guochun, Z., Liang, H., Mengrui, W., Hongliang, C. and Yi-Ping, L. (2013) C/EBPα regulates osteoclast lineage commitment. Proc. Natl. Acad. Sci. USA, 110, 72947299.
  • Weinstein, R.S. and Hutson, M.S. (1987) Decreased trabecular width and increased trabecular spacing contribute to bone loss with aging. Bone 8, 137142.
  • Winkel, B.S. (2004) Metabolic channeling in plants. Annu. Rev. Plant Biol. 55, 85.
  • Winkel-Shirley, B. (2001) Flavonoid biosynthesis: a colorful model for genetics, biochemistry, cell biology and biotechnology. Plant Physiol. 126, 485493.
  • Yi, J., Derynck, M.R., Li, X., Telmer, P., Marsolais, F. and Dhaubhadel, S. (2010) A single-repeat MYB transcription factor, GmMYB176, regulates CHS8 gene expression and affects isoflavonoid biosynthesis in soybean. Plant J. 62, 10191034.
  • Yu, O., Jung, W., Shi, J., Croes, R.A., Fader, G.M., McGonigle, B. and Odell, J.T. (2000) Production of the isoflavones genistein and daidzein in non-legume dicot and monocot tissues. Plant Physiol. 124, 781794.