Letter to the Editor
Reduced expression of nuclear Dicer correlates with melanoma progression
Version of Record online: 21 NOV 2012
© 2012 John Wiley & Sons A/S
Pigment Cell & Melanoma Research
Volume 26, Issue 1, pages 147–149, January 2013
How to Cite
Jafarnejad, S. M., Sjoestroem, C., Ardekani, G. S., Martinka, M. and Li, G. (2013), Reduced expression of nuclear Dicer correlates with melanoma progression. Pigment Cell & Melanoma Research, 26: 147–149. doi: 10.1111/pcmr.12039
- Issue online: 17 DEC 2012
- Version of Record online: 21 NOV 2012
- Accepted manuscript online: 19 OCT 2012 12:38AM EST
- Canadian Institutes of Health Research. Grant Numbers: MOP-93810, MOP-110974, CCI-117958
- Canadian Dermatology Foundation
- University of British Columbia Graduate Fellowship
Data S1. Materials and Methods.
Figure S1. Chi-square test for differences in nuclear Dicer staining at different stages of melanoma progression.
Figure S2. Tissue microarray staining using a second monoclonal anti-Dicer antibody (Clonegene).
Figure S3. Monoclonal antibody against Dicer (Clonegene) confirms the positive correlation between nuclear Dicer expression and melanoma patient survival.
Figure S4. Cytoplasmic and nuclear signals of monoclonal anti-Dicer antibody are impeded by the blocking peptide, compared with staining with anti-Dicer antibody alone.
Table S1. Nuclear Dicer staining and clinicopathologic characteristics of 262 primary melanomas (Sigma antibody).
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