Decreased regulatory T-cells and CD4+/CD8+ ratio correlate with disease onset and progression in patients with generalized vitiligo
Article first published online: 13 MAY 2013
© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Pigment Cell & Melanoma Research
Volume 26, Issue 4, pages 586–591, July 2013
How to Cite
Dwivedi, M., Laddha, N. C., Arora, P., Marfatia, Y. S. and Begum, R. (2013), Decreased regulatory T-cells and CD4+/CD8+ ratio correlate with disease onset and progression in patients with generalized vitiligo. Pigment Cell & Melanoma Research, 26: 586–591. doi: 10.1111/pcmr.12105
- Issue published online: 26 JUN 2013
- Article first published online: 13 MAY 2013
- Accepted manuscript online: 10 APR 2013 04:52AM EST
- Manuscript Accepted: 8 APR 2013
- Manuscript Received: 31 DEC 2012
|pcmr12105-sup-0001-DataS1.doc||Word document||38K||Data S1. Materials and methods.|
|pcmr12105-sup-0002-FigureS1.tif||image/tif||3414K||Figure S1. (A) Human CD4+ and CD8+ T-cell subsets identified by FACS analysis (representative FACS plots for CD4+ and CD8+ T-cells). (B) Characterization of human Treg (CD4+CD25hiFoxP3+) population by FACS analysis (representative FACS plots for Treg (CD4+CD25hiFoxP3+) cells).|
|pcmr12105-sup-0003-FigureS2.tif||image/tif||2579K||Figure S2. CD4+ and CD8+ T-cell counts and CD4+/CD8+ ratio in male and female patients with GV.|
|pcmr12105-sup-0004-FigureS3.tif||image/tif||3677K||Figure S3. Back gating strategy for CD4+CD25hiFoxP3+ regulatory T cells (Tregs).|
|pcmr12105-sup-0005-FigureS4.tif||image/tif||4714K||Figure S4. CD4+CD25hiFoxP3+ regulatory T cells (Tregs) in healthy controls.|
|pcmr12105-sup-0006-TableS1-S2.doc||Word document||42K|| |
Table S1. Demographic characteristics of generalized vitiligo (GV) patients and unaffected controls.
Table S2. Counts of CD4+ and CD8+ T cells and CD4+ /CD8+ ratio with respect to age of onset of generalized vitiligo (GV).
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