Diabetes, physical activity participation and exercise capacity in patients with schizophrenia
Article first published online: 13 AUG 2013
© 2013 The Authors. Psychiatry and Clinical Neurosciences © 2013 Japanese Society of Psychiatry and Neurology
Psychiatry and Clinical Neurosciences
Volume 67, Issue 6, pages 451–456, September 2013
How to Cite
Vancampfort, D., De Hert, M., Sweers, K., De Herdt, A., Detraux, J. and Probst, M. (2013), Diabetes, physical activity participation and exercise capacity in patients with schizophrenia. Psychiatry and Clinical Neurosciences, 67: 451–456. doi: 10.1111/pcn.12077
- Issue published online: 2 SEP 2013
- Article first published online: 13 AUG 2013
- Manuscript Accepted: 10 MAY 2013
- Manuscript Revised: 2 MAY 2013
- Manuscript Received: 13 NOV 2012
- physical activity;
- physical fitness;
The aim of this study was to determine if in schizophrenia patients the presence of diabetes is associated with lower physical activity participation and lower exercise capacity compared to patients with pre-diabetes and to patients without (pre-) diabetes.
Schizophrenia patients without (pre-)diabetes (n = 86) were compared with pre-diabetic (n = 10) and diabetic patients (n = 10). Patients were assessed on physical activity participation using the Baecke physical activity questionnaire and on exercise capacity using a 6-min walk test (6MWT).
The three groups were similar in age, sex, mean antipsychotic medication dose, negative and depressive symptoms and smoking behavior. Distance achieved on the 6MWT, however, was approximately 15% shorter (P < 0.05) in patients withdiabetes than in patients without (pre-)diabetes (500.3 ± 76.9 m vs 590.7 ± 101.8 m). Patients with diabetes were also significantly less physically active (P < 0.05). No differences between diabetic and pre-diabetic patients were found. Pre-diabetic patients had a higher body mass index (BMI) than non-diabetic patients (30.0 ± 7.3 vs 24.3 ± 4.3, P < 0.05). An interaction effect with BMI for differences in Baecke (F = 29.9, P < 0.001) and 6MWT (F = 13.0, P < 0.001) scores was seen between diabetic and non-diabetic patients on univariate ANCOVA.
The additive burden of diabetes might place patients with schizophrenia at an even greater risk for functional limitations in daily life.