Performance on the Wechsler Adult Intelligence Scale-III in Japanese patients with schizophrenia
Article first published online: 17 MAR 2014
© 2014 The Authors. Psychiatry and Clinical Neurosciences © 2014 Japanese Society of Psychiatry and Neurology
Psychiatry and Clinical Neurosciences
Volume 68, Issue 7, pages 534–541, July 2014
How to Cite
Fujino, H., Sumiyoshi, C., Sumiyoshi, T., Yasuda, Y., Yamamori, H., Ohi, K., Fujimoto, M., Umeda-Yano, S., Higuchi, A., Hibi, Y., Matsuura, Y., Hashimoto, R., Takeda, M. and Imura, O. (2014), Performance on the Wechsler Adult Intelligence Scale-III in Japanese patients with schizophrenia. Psychiatry and Clinical Neurosciences, 68: 534–541. doi: 10.1111/pcn.12165
- Issue published online: 4 JUL 2014
- Article first published online: 17 MAR 2014
- Accepted manuscript online: 22 JAN 2014 03:13AM EST
- Manuscript Accepted: 15 JAN 2014
- Manuscript Revised: 7 JAN 2014
- Manuscript Received: 13 MAR 2013
- Japanese Ministry of Health, Labor and Welfare. Grant Number: H22-seishin-ippan-001
- Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT) KAKENHI. Grant Numbers: 22390225, 23659565, 221S0003
- Japan Foundation for Neuroscience and Mental Health
- Strategic Research Program
- cognitive impairment;
- cross-national difference;
- functional outcome;
- Wechsler Adult Intelligence Scale-III
Patients with schizophrenia have been reported to perform worse than non-schizophrenic populations on neuropsychological tests, which may be affected by cultural factors. The aim of this study was to examine the performance of a sizable number of patients with schizophrenia on the Japanese version of the Wechsler Adult Intelligence Scale-III (WAIS-III) compared with healthy controls.
Performance on the WAIS-III was evaluated in 157 Japanese patients with schizophrenia and in 264 healthy control subjects.
All IQ scores and four indices from the WAIS-III were impaired for patients with schizophrenia compared with healthy controls. Processing Speed was markedly disturbed, approximately 2 SD below that of the healthy control group. Among the 13 subtests, Comprehension (z = −1.70, d = 1.55), Digit Symbol Coding (z = −1.84, d = 1.88), and Symbol Search (z = −1.85, d = 1.77) were profoundly impaired relative to the healthy controls.
These results indicate that the pattern and degree of impairment, as evaluated by the WAIS-III, in Japanese patients are similar to those previously reported in English-speaking patients and that the deficits of some neuropsychological domains relevant to functional outcomes are universally characteristic of schizophrenia.