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Two Cases of Hemihyperplasia–Multiple Lipomatosis Syndrome and Review of Asymmetric Hemihyperplasia Syndromes

Authors

  • Brittany G. Craiglow M.D.,

    Corresponding author
    1. Department of Dermatology, School of Medicine, Yale University, New Haven, Connecticut
    • Address correspondence to Brittany Craiglow, M.D., Department of Dermatology, School of Medicine, Yale University, PO Box 208059, New Haven, CT 06520, or e-mail: brittany.craiglow@yale.edu.

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  • Christine J. Ko M.D.,

    1. Department of Dermatology, School of Medicine, Yale University, New Haven, Connecticut
    2. Department of Dermatopathology, School of Medicine, Yale University, New Haven, Connecticut
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  • Richard J. Antaya M.D.

    1. Department of Dermatology, School of Medicine, Yale University, New Haven, Connecticut
    2. Department of Pediatrics, School of Medicine, Yale University, New Haven, Connecticut
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  • These cases were presented at a meeting of the New England Dermatological Society, Yale University, New Haven, Connecticut, October 1, 2011.

Abstract

Hemihyperplasia–multiple lipomatosis syndrome (HHML) is a condition characterized by asymmetric nonprogressive overgrowth, multiple lipomas, and superficial vascular malformations. We present two cases of HHML to enhance the diagnostic acumen of dermatologists and avoid potential misdiagnosis of this rare but probably underrecognized entity. We also provide a brief review of asymmetric overgrowth syndromes, which have overlapping yet distinct clinical manifestations.

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