An Unusual Case of Dermatitis Herpetiformis
Article first published online: 14 FEB 2013
© 2013 Wiley Periodicals, Inc.
Volume 31, Issue 4, pages 511–514, July/August 2014
How to Cite
Clark, K., Powers, R. and Kovach, R. (2014), An Unusual Case of Dermatitis Herpetiformis. Pediatric Dermatology, 31: 511–514. doi: 10.1111/pde.12086
- Issue published online: 14 JUL 2014
- Article first published online: 14 FEB 2013
An adolescent boy whose initial presentation consisted of an asymmetric, nonvesicular rash was eventually diagnosed with dermatitis herpetiformis (DH). Certain factors, including lesions limited to the genitals, an initial biopsy revealing nonspecific findings on microscopy studies, and the absence of characteristic direct immunofluorescence findings lessened initial clinical suspicions of DH over that of scabies infestation. Classic microscopic findings of DH were identified on repeat biopsy. Serologic studies revealed immunoglobulin A (IgA) endomysial and IgA tissue transglutaminase positivity. Response to dapsone proved dramatic. Histopathologic findings, serology, and response to treatment rather than classical clinical findings and direct immunofluorescence supported the diagnosis of DH in this case.