Pyoderma Gangrenosum Associated with an Aseptic Splenic Abscess in a Patient with Neurofibromatosis
Article first published online: 28 MAR 2013
© 2013 Wiley Periodicals, Inc.
How to Cite
Johnson, J. L., West, D. A. and Haggstrom, A. N. (2013), Pyoderma Gangrenosum Associated with an Aseptic Splenic Abscess in a Patient with Neurofibromatosis. Pediatric Dermatology. doi: 10.1111/pde.12129
- Article first published online: 28 MAR 2013
Pyoderma gangrenosum (PG) is a painful, ulcerating neutrophilic dermatosis commonly associated with a variety of underlying systemic conditions. We report a child with neurofibromatosis-1 (NF-1) and an aseptic splenic abscess who developed multifocal PG in areas of iatrogenic skin trauma. There is no clinical evidence or theoretical basis to suggest a causal relationship between NF-1 and PG. Systemic corticosteroid and cyclosporine therapy led to complete resolution of the lesions.