Crohn's Disease Presenting as a Neutrophilic Dermatosis in a 5-Month-Old Boy


Address correspondence to Kristi M. Canty, M.D., Division of Pediatric Dermatology, Children's Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, or e-mail:


A 5-month-old boy with a previous history of failure to thrive and poor feeding was admitted to the hospital with failure to thrive, oral ulcers, and a generalized vesiculopustular rash that demonstrated a subcorneal pustule and neutrophilic infiltrate on histology. Esophagogastroduodenoscopy and flexible sigmoidoscopy biopsies demonstrated chronic active colitis with granulomas, consistent with the diagnosis of Crohn's disease. Our case represents, to our knowledge, the youngest person reported with this condition in association with Crohn's disease.