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Plaque-Like Myofibroblastic Tumor: Report of Three Cases


Address correspondence to Ann L. Marqueling, M.D., Department of Dermatology, Stanford University, 700 Welch Road, Suite 301, Palo Alto, CA 94305, or e-mail:


Plaque-like myofibroblastic tumor of infancy (PMTI) was first reported in 2007. The first two cases described large, plaque-like tumors presenting in infancy with microscopic features consistent with dermatofibroma but with immunohistochemical features of myofibrocytic lineage. We present three additional cases of PMTI, the first cases reported since the initial two cases, and describe additional clinical features of this condition, including presentation in early childhood as opposed to infancy, development of ulceration, and aggressive growth. We propose shortening the name of this condition to plaque-like myofibroblastic tumor because presentation can occur in infancy or in early childhood.