Aplasia Cutis Congenita in a Setting of Fetus Papyraceus Associated with Small Fetal Abdominal Circumference and High Alpha-Fetoprotein and Amniotic Acetylcholinesterase
Article first published online: 11 OCT 2013
© 2013 Wiley Periodicals, Inc.
Volume 32, Issue 1, pages 138–140, January/February 2015
How to Cite
Mazza, J. M., Klein, J. F., Christopher, K. and Silverberg, N. B. (2015), Aplasia Cutis Congenita in a Setting of Fetus Papyraceus Associated with Small Fetal Abdominal Circumference and High Alpha-Fetoprotein and Amniotic Acetylcholinesterase. Pediatric Dermatology, 32: 138–140. doi: 10.1111/pde.12228
- Issue published online: 21 JAN 2015
- Article first published online: 11 OCT 2013
Fetus papyraceus is the fetal death of one or more fetuses in a multiparous pregnancy. The surviving infants can experience extensive aplasia cutis in an H-shaped distribution over the flanks and abdomen as a consequence of the loss of their fetal sibling. We report the case of a monochorionic, diamniotic pregnancy complicated by a single fetal death at 13 weeks of gestational age. Aplasia cutis of the surviving twin was suggested in utero by three criteria: high amniotic and maternal alpha-fetoprotein, detectable acetylcholinesterase, and small abdominal circumference on prenatal ultrasound. This constellation of findings in the setting of fetus papyraceus can be an indicator of aplasia cutis in the surviving fetus.