Oral Glycopyrrolate for Refractory Pediatric and Adolescent Hyperhidrosis
Article first published online: 25 NOV 2013
© 2013 Wiley Periodicals, Inc.
Volume 31, Issue 1, pages e28–e30, January/February 2014
How to Cite
Kumar, M. G., Foreman, R. S., Berk, D. R. and Bayliss, S. J. (2014), Oral Glycopyrrolate for Refractory Pediatric and Adolescent Hyperhidrosis. Pediatric Dermatology, 31: e28–e30. doi: 10.1111/pde.12236
- Issue published online: 7 JAN 2014
- Article first published online: 25 NOV 2013
Primary hyperhidrosis is a common disorder affecting children and adolescents, and it can have a significant negative psychosocial effect. Treatment for pediatric hyperhidrosis tends to be limited by low efficacy, low adherence, and poor tolerance. Oral glycopyrrolate is emerging as a potential second-line treatment option, but experience with safety, efficacy, and dosing is especially limited in children. We present an institutional review of 12 children with severe, refractory hyperhidrosis treated with oral glycopyrrolate; 11 (92%) noted improvement and 9 (75%) would recommend oral glycopyrrolate to their friends. No significant side effects were noted. Our retrospective analysis suggests that oral glycopyrrolate is safe and effective in children with hyperhidrosis.