Nevus Comedonicus in Oral-Facial-Digital Syndrome Type 1: A New Finding or Overlapping Syndromes?
Article first published online: 11 FEB 2014
© 2014 Wiley Periodicals, Inc.
Volume 31, Issue 2, pages e48–e51, March/April 2014
How to Cite
Baker, L. A. and Agim, N. G. (2014), Nevus Comedonicus in Oral-Facial-Digital Syndrome Type 1: A New Finding or Overlapping Syndromes?. Pediatric Dermatology, 31: e48–e51. doi: 10.1111/pde.12278
- Issue published online: 9 MAR 2014
- Article first published online: 11 FEB 2014
We report a patient with oral-facial-digital syndrome type 1 (OFDS1) who exhibited features overlapping those of nevus comedonicus syndrome, an unusual presentation that may potentially represent a new variant of OFDS1. OFDS1 and nevus comedonicus syndrome represent two rare syndromes with numerous overlapping features that have yet to be described in relation to one another. The features present in our patient led us to propose the possibility of a new variant of OFDS1 in which nevus comedonicus represents a cutaneous manifestation of the syndrome. Knowledge of this potential relationship is important for identification and management of the syndromes' accompanying manifestations in affected patients and may offer further insight into crossroads of pathogenesis.