Clinical and Laboratory Investigation
Pustular Psoriasis in Childhood and Adolescence: A 20-Year Single-Center Experience
Article first published online: 6 MAR 2014
© 2014 Wiley Periodicals, Inc.
Volume 31, Issue 5, pages 575–579, September/October 2014
How to Cite
Popadic, S. and Nikolic, M. (2014), Pustular Psoriasis in Childhood and Adolescence: A 20-Year Single-Center Experience. Pediatric Dermatology, 31: 575–579. doi: 10.1111/pde.12296
- Issue published online: 4 SEP 2014
- Article first published online: 6 MAR 2014
- Ministry of Education and Science of the Republic of Serbia. Grant Numbers: 175065, 175038
Pustular psoriasis (PP) is rare in children. The small number of reported cases makes deciding on treatment and follow-up challenging. The current study was an evaluation of treatment approaches and courses of PP in 18 children diagnosed and followed over a 20-year period. From 1992 to 2011 we treated 1,447 children with psoriasis, 18 of whom had PP. Follow-up was 2 to 19 years. At the time of initial manifestation of PP, our patients were 1.5 months to 16 years old. Seven patients had a previous history of psoriasis vulgaris. Three children entered long-term remission after one pustular attack, 10 developed psoriasis vulgaris, 2 are currently under treatment, and 3 were lost to follow-up. Treatment with acitretin, cyclosporine, or methotrexate was efficacious and well tolerated. PP is rare, but according to our experience, it has a good prognosis in children.