Quantification of Glucose Diffusion in Human Lung Tissues by Using Fourier Domain Optical Coherence Tomography (pages 311–316)
Xiao Guo, Guoyong Wu, Huajiang Wei, Xiaoyuan Deng, Hongqin Yang, Yanhong Ji, Yonghong He, Zhouyi Guo, Shusen Xie, Huiqing Zhong, Qingliang Zhao and Zhenguo Zhu
Article first published online: 17 JAN 2012 | DOI: 10.1111/j.1751-1097.2011.01065.x
This figure represents the comparison of permeability coefficients (PCs) of 30% glucose diffusion in normal, benign granulomatosis, adenocarcinoma tumor and squamous cell carcinoma of human lung tissue in vitro. A fourier domain optical coherence tomography (FD OCT) system was used for experimentation. PCs were computed by analyzing the OCT signal slope changes induced by the agent diffusion in a specific depth region. Our results show that PCs of the same hyperosmotic agent in normal, benign and malignant lung tissues are apparently different. Therefore, FD OCT might provide a truly noninvasive way to evaluate of normal and abnormal tissues.