Disclosure information/Acknowledgment of support: No other staff has been involved in this study.
Original Research Article
Experimental Knee Pain Evoke Spreading Hyperalgesia and Facilitated Temporal Summation of Pain
Article first published online: 16 APR 2013
Wiley Periodicals, Inc
Volume 14, Issue 6, pages 874–883, June 2013
How to Cite
Joergensen, T. S., Henriksen, M., Danneskiold-Samsoee, B., Bliddal, H. and Graven-Nielsen, T. (2013), Experimental Knee Pain Evoke Spreading Hyperalgesia and Facilitated Temporal Summation of Pain. Pain Medicine, 14: 874–883. doi: 10.1111/pme.12093
TSJ: main author of the manuscript; data collection, data analysis and writing.
MH: contributed to the analysis and discussed and commented on the whole paper.
BDS: discussed and commented on the whole paper and protocols.
HB: discussion and commented on the whole paper and protocols.
TGN: main responsible for outlining the manuscript, discussing, and commenting on the paper during the whole process.
Experimental knee pain leads to hyperalgesia at the knee and facilitated temporal summation of pain outside the knee, indicating involvement of peripheral and central sensitization, in subjects with no history of knee pain. Experimental models of knee pain in healthy subjects may be advantageous to investigate mechanisms of the nociceptive system related to joint pain without any unwanted variability.
- Issue published online: 20 JUN 2013
- Article first published online: 16 APR 2013
- Oak Foundation
- Center for Sensory Motor Interaction (SMI) at Aalborg University
- The Danish Agency for Science Technology and Innovation (FI)
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