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Group Interpersonal and Social Rhythm Therapy for Bipolar Depression

Authors

  • Astrid A. Hoberg DNP, RN, PMHCNS-BC,

    Clinical Nurse Specialist, Corresponding author
    • Department of Psychiatry and Psychology, Mayo Clinic Depression Center, Mayo Clinic, Rochester, Minnesota, USA
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  • Julie Ponto PhD, RN, ACNS-BC, AOCNS®,

    Professor
    1. College of Nursing and Health Sciences, Winona State University-Rochester, Winona, Minnesota, USA
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  • Pamela J. Nelson PhD, RN, PMHCNS-BC,

    Assistant Professor
    1. College of Nursing and Health Sciences, Winona State University-Rochester, Winona, Minnesota, USA
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  • Mark A. Frye MD

    Psychiatrist and Department Chair
    1. Department of Psychiatry and Psychology, Mayo Clinic Depression Center, Mayo Clinic, Rochester, Minnesota, USA
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  • Conflict of Interest Statement
  • Astrid A. Hoberg, Julie Ponto, and Pamela J. Nelson report no actual or potential conflicts of interest.
  • Mark A. Frye Disclosure
  • Grant Support—Pfizer, National Alliance for Schizophrenia and Depression (NARSAD), National Institute of Mental Health (NIMH), National Institute of Alcohol Abuse and Alcoholism (NIAAA), Mayo Foundation
  • Consultant—Dainippon Sumittomo Pharma, Merck, Sepracor
  • CME Supported Activity—Astra-Zeneca, Bristol-Myers Squibb, Eli Lilly and Co., GlaxoSmithKline, Merck, Otsuka Pharmaceuticals, Pfizer, Sanofi-Aventis
  • Speakers' Bureau—None
  • Financial Interest/Stock Ownership/Royalties—None

Author contact:

hoberg.astrid@mayo.edu, with a copy to the Editor: gpearson@uchc.edu

Abstract

Purpose

To evaluate the feasibility of 2-week interpersonal and social rhythm therapy group (IPSRT-G) for bipolar depression.

Design and Methods

Participants with bipolar depression received two individual sessions, six IPSRT-G sessions, and a 12-week telephone call. The Inventory of Depressive Symptomatology-Clinician Rated (IDS-C), Young Mania Rating Scale (YMRS), Sheehan Disability Scale (SDS), and Clinical Global Impressions-Bipolar Version (CGI-BP) were used.

Findings

IDS-C and SDS scores improved significantly at 12 weeks. YMRS and CGI-BP scores improved but did not reach statistical significance.

Practice Implications

The promising antidepressive response supports further study of IPSRT-G for bipolar depression.

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