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The Effect of Nurse-Led Motivational Interviewing on Medication Adherence in Patients With Bipolar Disorder


  • Conflict of Interest Statement

    The authors report no actual or potential conflicts of interest.



The purpose of this study was to test the effect of motivational interviewing (MI) on medication adherence in patients with bipolar disorder (BD) in an outpatient setting.

Design and Methods

Pretest–posttest design was used. The 3-week MI intervention consisted of one face-to-face session and two follow-up telephone interventions. Outcome measures included medication adherence, self-efficacy, and motivation to change.


Participants demonstrated significant improvement in medication adherence, self-efficacy, and motivation to change after receiving the MI.

Practice Implications

MI shows promising results as a treatment approach to improve medication adherence in adults with BD. Psychiatric-mental health nurse practitioners could improve client health outcomes by implementing MI techniques.