The authors gratefully thank Dr. Mark Halaki for his advice on statistical analyses, the authors of ERI, PSS, and PSQI for permission to translate, validate, and use their questionnaires, and Sukina Medical Laboratory for providing laboratory facilities to conduct biochemical testing.
Associations among work-related stress, cortisol, inflammation, and metabolic syndrome
Article first published online: 12 JUN 2013
Copyright © 2013 Society for Psychophysiological Research
Volume 50, Issue 9, pages 821–830, September 2013
How to Cite
Almadi, T., Cathers, I. and Chow, C. M. (2013), Associations among work-related stress, cortisol, inflammation, and metabolic syndrome. Psychophysiology, 50: 821–830. doi: 10.1111/psyp.12069
- Issue published online: 15 AUG 2013
- Article first published online: 12 JUN 2013
- Manuscript Accepted: 23 APR 2013
- Manuscript Received: 21 AUG 2012
This cross-sectional study examined the relationship between work-related stress, cortisol, and C-reactive protein (CRP) in predicting metabolic syndrome (MtS). Self-reported work stress measured by the effort reward imbalance ratio (ERI), anthropometric data, CRP, and saliva cortisol were collected from 204 healthy Jordanian male workers. ERI and cortisol were significantly associated with the presence of MtS (OR = 4.74, 95% CI: 2.13–10.55; OR = 3.03, 95% CI: 2.08–4.40; OR = 11.50, 95% CI: 2.16–59.14, respectively). The odds of MtS in men with high ERI and high cortisol were significantly higher than that of men with low ERI and low cortisol (OR = 11.50, 95% CI: 2.16–59.14). CRP was significantly associated with MtS (OR = 2.51, 95% CI: 1.50–4.20). The odds of MtS were significantly higher in centrally obese men with both high ERI and CRP level. Thus, high ERI along with high cortisol or high CRP increases the risk for MtS, especially among centrally obese men.