Research reported in this publication was supported by the National Institute on Drug Abuse under award numbers R37DA005147 and R01DA024417. Additionally, the first author was supported by T32 grant MH017069 from the National Institute of Mental Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Characterizing electrodermal response habituation: A latent class approach with application to psychopathology
Article first published online: 4 JUL 2013
Copyright © 2013 Society for Psychophysiological Research
Volume 50, Issue 10, pages 954–962, October 2013
How to Cite
Isen, J. D., Iacono, W. G. and Malone, S. M. (2013), Characterizing electrodermal response habituation: A latent class approach with application to psychopathology. Psychophysiology, 50: 954–962. doi: 10.1111/psyp.12080
- Issue published online: 23 SEP 2013
- Article first published online: 4 JUL 2013
- Manuscript Accepted: 9 MAY 2013
- Manuscript Received: 3 NOV 2012
- National Institute on Drug Abuse. Grant Numbers: R37DA005147, R01DA024417
- National Institute of Mental Health. Grant Number: MH017069
- Substance dependence;
Response habituation is a fundamental form of nonassociative learning, yet there are substantial individual differences in its electrodermal manifestation. We employed a latent class analysis to identify discrete groups of electrodermal responders to a series of loud tones. We also evaluated whether heterogeneity in responsiveness was associated with lifetime prevalence of externalizing psychopathology and major depression. Participants were community-recruited men (N = 1,141) who underwent a standard habituation paradigm. A latent class analysis resulted in the identification of four electrodermal populations: rapid habituators, habituators, and two classes that showed weak response habituation, but differed markedly in their amplitude profiles. Relative to rapid habituators, members of slower habituating classes were less likely to receive lifetime diagnoses of antisocial personality disorder and substance dependence. Further research using this analytical strategy could help identify the functional significance of individual differences in habituation.