Respirology

Cover image for Vol. 16 Issue 2

February 2011

Volume 16, Issue 2

Pages 185–380

  1. EDITORIALS

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES: RESPIRATORY HEALTH ISSUES IN THE ASIA–PACIFIC REGION
    4. INVITED REVIEW SERIES: CUTTING EDGE TECHNOLOGIES
    5. INVITED REVIEW SERIES: PLEURAL DISEASE
    6. REVIEW
    7. MEDICAL HYPOTHESIS
    8. ORIGINAL ARTICLES
    9. CORRESPONDENCE
    10. FORTHCOMING MEETINGS
    11. JOURNAL STATISTICS
    1. You have free access to this content
      Impaired swallow in COPD (pages 185–186)

      Bhajan Singh

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01903.x

    2. You have free access to this content
  2. INVITED REVIEW SERIES: RESPIRATORY HEALTH ISSUES IN THE ASIA–PACIFIC REGION

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES: RESPIRATORY HEALTH ISSUES IN THE ASIA–PACIFIC REGION
    4. INVITED REVIEW SERIES: CUTTING EDGE TECHNOLOGIES
    5. INVITED REVIEW SERIES: PLEURAL DISEASE
    6. REVIEW
    7. MEDICAL HYPOTHESIS
    8. ORIGINAL ARTICLES
    9. CORRESPONDENCE
    10. FORTHCOMING MEETINGS
    11. JOURNAL STATISTICS
    1. You have free access to this content
    2. You have free access to this content
      The effects of bushfire smoke on respiratory health (pages 198–209)

      Martine DENNEKAMP and Michael J. ABRAMSON

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01868.x

  3. INVITED REVIEW SERIES: CUTTING EDGE TECHNOLOGIES

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES: RESPIRATORY HEALTH ISSUES IN THE ASIA–PACIFIC REGION
    4. INVITED REVIEW SERIES: CUTTING EDGE TECHNOLOGIES
    5. INVITED REVIEW SERIES: PLEURAL DISEASE
    6. REVIEW
    7. MEDICAL HYPOTHESIS
    8. ORIGINAL ARTICLES
    9. CORRESPONDENCE
    10. FORTHCOMING MEETINGS
    11. JOURNAL STATISTICS
    1. You have free access to this content
      The next generation: Using new sequencing technologies to analyse gene regulation (pages 210–222)

      Rebecca CULLUM, Olivia ALDER and Pamela A. HOODLESS

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01899.x

    2. You have free access to this content
      Cellular therapies for lung disease: A distant horizon (pages 223–237)

      Yuben MOODLEY, Ursula MANUELPILLAI and Daniel J. WEISS

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01914.x

  4. INVITED REVIEW SERIES: PLEURAL DISEASE

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES: RESPIRATORY HEALTH ISSUES IN THE ASIA–PACIFIC REGION
    4. INVITED REVIEW SERIES: CUTTING EDGE TECHNOLOGIES
    5. INVITED REVIEW SERIES: PLEURAL DISEASE
    6. REVIEW
    7. MEDICAL HYPOTHESIS
    8. ORIGINAL ARTICLES
    9. CORRESPONDENCE
    10. FORTHCOMING MEETINGS
    11. JOURNAL STATISTICS
    1. You have free access to this content
      Update on uncommon pleural effusions (pages 238–243)

      Jay H. RYU, Sara TOMASSETTI and Fabien MALDONADO

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01900.x

    2. You have free access to this content
      Pleural controversy: Optimal chest tube size for drainage (pages 244–248)

      Richard W. LIGHT

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01913.x

  5. REVIEW

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES: RESPIRATORY HEALTH ISSUES IN THE ASIA–PACIFIC REGION
    4. INVITED REVIEW SERIES: CUTTING EDGE TECHNOLOGIES
    5. INVITED REVIEW SERIES: PLEURAL DISEASE
    6. REVIEW
    7. MEDICAL HYPOTHESIS
    8. ORIGINAL ARTICLES
    9. CORRESPONDENCE
    10. FORTHCOMING MEETINGS
    11. JOURNAL STATISTICS
    1. You have free access to this content
      Basic principles and current applications of lung ultrasonography in the intensive care unit (pages 249–256)

      Konstantinos STEFANIDIS, Stavros DIMOPOULOS and Serafim NANAS

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01885.x

    2. You have free access to this content
      Genomic medicine in non-small cell lung cancer: Paving the path to personalized care (pages 257–263)

      Krishna Bajee SRIRAM, Jill Everland LARSEN, Ian Anthony YANG, Rayleen Veronica BOWMAN and Kwun Meng FONG

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01892.x

  6. MEDICAL HYPOTHESIS

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES: RESPIRATORY HEALTH ISSUES IN THE ASIA–PACIFIC REGION
    4. INVITED REVIEW SERIES: CUTTING EDGE TECHNOLOGIES
    5. INVITED REVIEW SERIES: PLEURAL DISEASE
    6. REVIEW
    7. MEDICAL HYPOTHESIS
    8. ORIGINAL ARTICLES
    9. CORRESPONDENCE
    10. FORTHCOMING MEETINGS
    11. JOURNAL STATISTICS
    1. A hypothesis to phenotype COPD exacerbations by aetiology (pages 264–268)

      Martin MacDONALD, Richard W. BEASLEY, Louis IRVING and Philip G. BARDIN

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01908.x

  7. ORIGINAL ARTICLES

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES: RESPIRATORY HEALTH ISSUES IN THE ASIA–PACIFIC REGION
    4. INVITED REVIEW SERIES: CUTTING EDGE TECHNOLOGIES
    5. INVITED REVIEW SERIES: PLEURAL DISEASE
    6. REVIEW
    7. MEDICAL HYPOTHESIS
    8. ORIGINAL ARTICLES
    9. CORRESPONDENCE
    10. FORTHCOMING MEETINGS
    11. JOURNAL STATISTICS
    1. Laryngeal penetration and aspiration in individuals with stable COPD (pages 269–275)

      Lydia CVEJIC, Richard HARDING, Thomas CHURCHWARD, Anthony TURTON, Paul FINLAY, David MASSEY, Philip G. BARDIN and Paul GUY

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01875.x

      Aspiration during swallow has never been shown in COPD. Using sub-mandibular videofluoroscopy during swallow of graduated volumes of barium, we show for the first time convincing aspiration of liquid material in stable COPD. The abnormality may be associated with distinctive patterns of breathing and swallow found in COPD.

    2. Pulmonary rehabilitation improves exercise capacity and quality of life in underweight patients with chronic obstructive pulmonary disease (pages 276–283)

      Chou-Chin LAN, Mei-Chen YANG, Chih-Hsin LEE, Yi-Chih HUANG, Chun-Yao HUANG, Kuo-Liang HUANG and Yao-Kuang WU

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01895.x

      This study confirmed that impairment of exercise capacity and health-related quality of life was greater in underweight compared with non-underweight COPD patients. Exercise training resulted in significant weight gains, and improvements in exercise capacity and health-related quality of life. Exercise training is indicated for underweight patients with COPD.

    3. Serum angiopoietin-2 levels are elevated during acute exacerbations of COPD (pages 284–290)

      Yu Ji CHO, Jeong Eun MA, Eun Young YUN, Yu Eun KIM, Ho Cheol KIM, Jong Deog LEE, Young Sil HWANG and Yi Yeong JEONG

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01915.x

      Serum angiopoietin-2 (Ang-2) levels were evaluated in individuals with COPD when stable and during acute exacerbations. Ang-2 levels were higher in individuals with acute exacerbations of COPD, as compared to individuals with stable disease, and correlated significantly with levels of CRP.

    4. Persistence of rhinovirus RNA and IP-10 gene expression after acute asthma (pages 291–299)

      Lisa G. WOOD, Heather POWELL, Terry V. GRISSELL, Bronwyn DAVIES, Darren R. SHAFREN, Bruce F. WHITEHEAD, Michael J. HENSLEY and Peter G. GIBSON

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01897.x

      Viral persistence is a recently recognized phenomenon. It is poorly characterized in asthma. This work defines the problem of viral persistence in asthma and examines the inflammatory consequences of this phenomenon.

    5. Secretory leukocyte protease inhibitor inhibits neutrophil apoptosis (pages 300–307)

      Devipriya SUBRAMANIYAM, Camilla HOLLANDER, Ulla WESTIN, Jonas ERJEFÄLT, Tim STEVENS and Sabina JANCIAUSKIENE

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01901.x

      Secretory leukocyte proteinase inhibitor (SLPI) is a major anti-elastase barrier at the epithelial surfaces of upper respiratory tract. Our findings indicate clear upregulation of SLPI in response to endotoxin in nasal secretions. In addition, SLPI shows dose-dependent anti-apoptotic and chemotactic effects on primary human neutrophils.

    6. Increased prevalence of primary drug-resistant pulmonary tuberculosis in immunocompromised patients (pages 308–313)

      Jung-Rern JIANG, Shiao-Yu YEN and Jann-Yuan WANG

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01902.x

      Drug-resistant tuberculosis (TB) is difficult to treat and is associated with a higher rate of mortality. The prevalence of primary pulmonary drug-resistant TB was higher but the incidence of drug-related adverse effects was similar in immunocompromised patients. In these patients, it is important to diagnose and investigate drug resistance before starting anti-TB treatment.

    7. Quantifying chronic cough: Objective versus subjective measurements (pages 314–320)

      Shoaib FARUQI, Rachel THOMPSON, Caroline WRIGHT, Wayne SHEEDY and Alyn H. MORICE

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01893.x

      In this study we look at the reproducibility and the association between objective cough counting, subjective cough questionnaires and experimental induction of cough. We demonstrate that the various forms of assessment of cough are reproducible. Cough counting correlates well with subjective assessment of cough and cough reflex sensitivity.

    8. Triggering receptor (TREM-1) expressed on myeloid cells predicts bacteremia better than clinical variables in community-acquired pneumonia (pages 321–325)

      Agustin RUIZ-GONZÁLEZ, Aureli ESQUERDA, Miquel FALGUERA, Nadia ABDULGHANI, Pamela CABEZAS, Silvia BIELSA and José M. PORCEL

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01905.x

      Blood cultures are used in the management of community-acquired pneumonia, although their cost-effectiveness has been questioned. This preliminary study suggest that the determination of serum sTREM-1 at admission may be more accurate than clinical variables for identifying bacteremic patients.

    9. The prevalence of pulmonary fibrosis combined with emphysema in patients with lung cancer (pages 326–331)

      Kazuhiro USUI, Chiharu TANAI, Yoshiaki TANAKA, Hiromichi NODA and Teruo ISHIHARA

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01907.x

      Data for 1143 patients with lung cancer was reviewed to assess the clinical characteristics of patients with lung cancer and CPFE. Patients with lung cancer and CPFE had a poor prognosis and 19.8% of these patients developed severe interstitial lung disease.

    10. Relationship of endotoxin and tobacco smoke exposure to wheeze and diurnal peak expiratory flow variability in children and adolescents (pages 332–339)

      Joshua A. LAWSON, James A. DOSMAN, Donna C. RENNIE, Jeremy BEACH, Stephen C. NEWMAN and Ambikaipakan SENTHILSELVAN

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01911.x

      Associations between domestic endotoxin exposures and wheezing symptoms and diurnal peak flow variation were examined among children with reported asthma or wheeze. The association between endotoxin exposure and exacerbations in children with asthma has been infrequently studied and the findings suggest that endotoxin exposure may worsen asthma in this group.

    11. Ambient particulate matter affects occludin distribution and increases alveolar transepithelial electrical conductance (pages 340–349)

      Juan C. CARABALLO, Cecilia YSHII, Whitney WESTPHAL, Thomas MONINGER and Alejandro P. COMELLAS

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01910.x

      This work studies the effects of particulate matter and diesel exhaust particles on alveolar barrier integrity in vitro. Our results show that these particles alter tight junction integrity, specifically the occludin and ZO-1 association. These effects are prevented by blocking of mitochondrial ROS production, suggesting a central role of this organelle in the effects observed.

    12. Comparison of tiotropium plus formoterol to tiotropium alone in stable chronic obstructive pulmonary disease: A meta-analysis (pages 350–358)

      Jianmiao WANG, Di JIN, Peng ZUO, Tao WANG, Yongjian XU and Weining XIONG

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01912.x

      A meta-analysis of eligible randomized controlled trials showed that in patients with stable COPD, tiotropium plus formoterol improved lung function and symptom scores compared with tiotropium alone, and there was a trend towards a decrease in adverse events in patients treated with the combination therapy.

    13. Functional haplotypes in the PTGDR gene fail to associate with asthma in two Australian populations (pages 359–366)

      Euzebiusz F. JAMROZIK, Nicole WARRINGTON, Jane MCCLENAGHAN, Jennie HUI, Arthur W. MUSK, Alan JAMES, John P. BEILBY, Janice HANSEN, Nicholas H. DE KLERK and Lyle J. PALMER

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01917.x

      Functional haplotypes in the PTGDR gene have been linked to asthma in Caucasians. In this study they were not significantly associated with asthma phenotypes or longitudinal decline in lung function in two Australian populations. A meta-analysis of previous studies in Caucasians demonstrated small but significant effects consistent with functional data.

    14. Rhinovirus infection induces expression of airway remodelling factors in vitro and in vivo (pages 367–377)

      Curtis KUO, Sam LIM, Nicholas J.C. KING, Nathan W. BARTLETT, Ross P. WALTON, Jie ZHU, Nicholas GLANVILLE, Julia ANISCENKO, Sebastian L. JOHNSTON, Janette K. BURGESS, Judith L. BLACK and Brian G. OLIVER

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01918.x

      Airway remodelling, as indicated by increased extracellular matrix production, was induced by rhinovirus in both in vitro and in vivo models. This study provides important information on the aetiology of asthmatic airway remodelling, which is integral to the pathogenesis of asthma.

      Corrected by:

      CORRIGENDUM

      Vol. 17, Issue 1, 192, Version of Record online: 21 DEC 2011

  8. CORRESPONDENCE

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES: RESPIRATORY HEALTH ISSUES IN THE ASIA–PACIFIC REGION
    4. INVITED REVIEW SERIES: CUTTING EDGE TECHNOLOGIES
    5. INVITED REVIEW SERIES: PLEURAL DISEASE
    6. REVIEW
    7. MEDICAL HYPOTHESIS
    8. ORIGINAL ARTICLES
    9. CORRESPONDENCE
    10. FORTHCOMING MEETINGS
    11. JOURNAL STATISTICS
    1. Response (page 379)

      Adnan Custovic, Angela Simpson, Philip G. Bardin and Peter Le Souëf

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2010.01916.x

  9. FORTHCOMING MEETINGS

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES: RESPIRATORY HEALTH ISSUES IN THE ASIA–PACIFIC REGION
    4. INVITED REVIEW SERIES: CUTTING EDGE TECHNOLOGIES
    5. INVITED REVIEW SERIES: PLEURAL DISEASE
    6. REVIEW
    7. MEDICAL HYPOTHESIS
    8. ORIGINAL ARTICLES
    9. CORRESPONDENCE
    10. FORTHCOMING MEETINGS
    11. JOURNAL STATISTICS
    1. FORTHCOMING MEETINGS (page 380)

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2011.01834_1.x

  10. JOURNAL STATISTICS

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES: RESPIRATORY HEALTH ISSUES IN THE ASIA–PACIFIC REGION
    4. INVITED REVIEW SERIES: CUTTING EDGE TECHNOLOGIES
    5. INVITED REVIEW SERIES: PLEURAL DISEASE
    6. REVIEW
    7. MEDICAL HYPOTHESIS
    8. ORIGINAL ARTICLES
    9. CORRESPONDENCE
    10. FORTHCOMING MEETINGS
    11. JOURNAL STATISTICS
    1. JOURNAL STATISTICS (page 380)

      Version of Record online: 27 JAN 2011 | DOI: 10.1111/j.1440-1843.2011.01834_2.x

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