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Figure S1 Individual changes in sputum malondialdehyde (MDA) values in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) stratified by tertiles for increases in forced expiratory volume in one second (ΔFEV1 % of predicted) post-treatment. Measurements were performed at the time of exacerbation (ex) and at discharge after hospital treatment (treat). Horizontal bars represent mean values. *P < 0.05 vs. exacerbation.

Table S1 Total and differential sputum cell counts in study subjects.

Table S2 The intra- and inter-assay repeatability and the between-day variability of malondialdehyde (MDA) measurements in sputum and exhaled breath condensate (EBC) collected from a subset (n = 12) of stable COPD patients.

Table S3 Changes in sputum malondialdehyde (MDA) concentrations in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) as assessed by increases in FEV1 after treatment.

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