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Respirology

Cover image for Respirology

February 2013

Volume 18, Issue 2

Pages 199–388

  1. EDITORIALS

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. INVITED REVIEW SERIES: TRANSLATING RESEARCH INTO PRACTICE
    6. REVIEWS
    7. ORIGINAL ARTICLES
    8. CLINICAL NOTE
    9. CORRESPONDENCES
    10. CORRIGENDA
    11. FORTHCOMING MEETINGS
    12. JOURNAL STATISTICS
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  2. SERIES EDITORIAL

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. INVITED REVIEW SERIES: TRANSLATING RESEARCH INTO PRACTICE
    6. REVIEWS
    7. ORIGINAL ARTICLES
    8. CLINICAL NOTE
    9. CORRESPONDENCES
    10. CORRIGENDA
    11. FORTHCOMING MEETINGS
    12. JOURNAL STATISTICS
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      Translating research into practice: An epilogue (pages 203–204)

      DAVID C.L. LAM and JOHN E. HEFFNER

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02281.x

  3. INVITED REVIEW SERIES

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. INVITED REVIEW SERIES: TRANSLATING RESEARCH INTO PRACTICE
    6. REVIEWS
    7. ORIGINAL ARTICLES
    8. CLINICAL NOTE
    9. CORRESPONDENCES
    10. CORRIGENDA
    11. FORTHCOMING MEETINGS
    12. JOURNAL STATISTICS
    1. Tuberculosis: Current State of Knowledge

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      Diagnosis and treatment of latent infection with Mycobacterium tuberculosis (pages 205–216)

      CYNTHIA BIN-ENG CHEE, MARTINA SESTER, WENHONG ZHANG and CHRISTOPH LANGE

      Article first published online: 25 JAN 2013 | DOI: 10.1111/resp.12002

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      Point-of-care diagnosis of tuberculosis: Past, present and future (pages 217–232)

      KEERTAN DHEDA, MORTEN RUHWALD, GRANT THERON, JONATHAN PETER and WING CHEONG YAM

      Article first published online: 25 JAN 2013 | DOI: 10.1111/resp.12022

  4. INVITED REVIEW SERIES: TRANSLATING RESEARCH INTO PRACTICE

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. INVITED REVIEW SERIES: TRANSLATING RESEARCH INTO PRACTICE
    6. REVIEWS
    7. ORIGINAL ARTICLES
    8. CLINICAL NOTE
    9. CORRESPONDENCES
    10. CORRIGENDA
    11. FORTHCOMING MEETINGS
    12. JOURNAL STATISTICS
    1. Translating Research into Practice

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  5. REVIEWS

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. INVITED REVIEW SERIES: TRANSLATING RESEARCH INTO PRACTICE
    6. REVIEWS
    7. ORIGINAL ARTICLES
    8. CLINICAL NOTE
    9. CORRESPONDENCES
    10. CORRIGENDA
    11. FORTHCOMING MEETINGS
    12. JOURNAL STATISTICS
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      Pleural effusions on the intensive care unit; Hidden morbidity with therapeutic potential (pages 246–254)

      ANDREW P. WALDEN, QUENTIN C. JONES, RAMPRASAD MATSA and MATTHEW P. WISE

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02279.x

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      Opioid effect on lungs (pages 255–262)

      TRAVIS YAMANAKA and RUXANA T. SADIKOT

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02307.x

  6. ORIGINAL ARTICLES

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. INVITED REVIEW SERIES: TRANSLATING RESEARCH INTO PRACTICE
    6. REVIEWS
    7. ORIGINAL ARTICLES
    8. CLINICAL NOTE
    9. CORRESPONDENCES
    10. CORRIGENDA
    11. FORTHCOMING MEETINGS
    12. JOURNAL STATISTICS
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      Systemic corticosteroids for community-acquired pneumonia: Reasons for use and lack of benefit on outcome (pages 263–271)

      EVA POLVERINO, CATIA CILLÓNIZ, POVILAS DAMBRAVA, ALBERT GABARRÚS, MIQUEL FERRER, CARLOS AGUSTÍ, ELENA PRINA, BEATRIZ MONTULL, ROSARIO MENENDEZ, MICHAEL S. NIEDERMAN and ANTONI TORRES

      Article first published online: 25 JAN 2013 | DOI: 10.1111/resp.12013

      Despite the lack of a clear benefit, systemic corticosteroids are frequently administered in CAP. We investigated clinical reasons for steroid prescription and the impact on major outcomes, showing no correlation with mortality or clinical stability independent of severity and cumulative steroid dosage, but an increase in length of hospital stay.

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      Inhaled corticosteroids increase the risk of oropharyngeal colonization by Streptococcus pneumoniae in children with asthma (pages 272–277)

      LINJIE ZHANG, SíLVIO O.M. PRIETSCH, ANA PAULA MENDES, ANDREA VON GROLL, GICELLE PORTO ROCHA, LILLIAN CARRION and PEDRO EDUARDO ALMEIDA DA SILVA

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02280.x

      This study shows that children with persistent asthma taking ICS are nearly four times as likely to have oropharyngeal colonization by S. pneumoniae as those not receiving ICS. These findings highlight the need for further studies to investigate the possible link between ICS and risk of respiratory infections in these patients.

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      Prognostic significance of fibroblastic foci in usual interstitial pneumonia and non-specific interstitial pneumonia (pages 278–283)

      TAISHI HARADA, KENTARO WATANABE, KAZUKI NABESHIMA, MAKOTO HAMASAKI and HIROSHI IWASAKI

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02272.x

      A significant correlation was demonstrated between histological findings and respiratory function in fibrosing interstitial pneumonia. Our findings indicate that fibroblastic foci are a reliable predictor of prognosis in usual interstitial pneumonia and fibrotic non-specific interstitial pneumonia.

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      Bronchoscopic practice in Japan: A survey by the Japan Society for Respiratory Endoscopy in 2010 (pages 284–290)

      FUMIHIRO ASANO, MOTOI AOE, YOSHINOBU OHSAKI, YOSHINORI OKADA, SHINJI SASADA, SHIGEKI SATO, EIICHI SUZUKI, HIROSHI SENBA, SHOZO FUJINO and KAZUMITSU OHMORI

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02273.x

      A questionnaire survey performed in Japan in 2010 (response rate: 95.0%) showed that mobile/thin bronchoscopes (outer diameter ≤4 mm) were used in ≥50% of the facilities accredited by our society, and fluoroscopy systems were used in 99.8%. Intravenous sedation was performed in only 36.1%.

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      Australasian respiratory and emergency physicians do not use the pneumonia severity index in community-acquired pneumonia (pages 291–296)

      DAVID J. SERISIER, SOPHIE WILLIAMS and SIMON D. BOWLER

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02275.x

      Australasian emergency and respiratory physicians infrequently use the PSI and are unable to apply it accurately. Two physician groups differed in their relative abilities to apply PSI and CURB-65, suggesting fragmented guideline dissemination. Australasian guidelines should promote a simple, coordinated pneumonia severity assessment tool that reaches across specialties.

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      Prevalence of undiagnosed and undertreated chronic obstructive pulmonary disease in lung cancer population (pages 297–302)

      JING ZHANG, JIE-BAI ZHOU, XIN-FENG LIN, QUN WANG, CHUN-XUE BAI and QUN-YING HONG

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02282.x

      This study showed that underdiagnosis and undertreatment of COPD remain substantial in lung cancer patients. Documentation of smoking history or respiratory symptoms promotes disease diagnosis. Education of COPD knowledge among patients and doctors and improvement of disease management are urgently required in this special population.

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      Relationship between the microsatellite D2S388-5 and D2S2232 polymorphisms and chronic obstructive pulmonary disease in the Chinese Kazakh population (pages 303–307)

      JIAN GUAN, XIAN-SHENG LIU, YONG-JIAN XU, XI-LIN XU, YONG-SHENG YANG and RAN WANG

      Article first published online: 25 JAN 2013 | DOI: 10.1111/resp.12000

      D2S388-5 polymorphism may be associated with susceptibility to COPD in Kazakh Chinese. The microsatellite polymorphism may be used as a genetic marker. More genes associated with the pathogenesis of COPD need to be identified to clarify the mechanism of COPD, which will aid the prevention of the disease.

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      Septic pulmonary embolism due to periodontal disease (pages 308–312)

      TAKESHI HATANI, MASAYA TAKEMURA, DAIKI INOUE, KAZUFUMI TAKAMATSU, MANABU ISHITOKO, RYO ITOTANI, SHINKO SUZUKI, MASATAKA MATSUMOTO, MINORU SAKURAMOTO and MOTONARI FUKUI

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02278.x

      SPE-PD is rarely reported. We retrospectively reviewed 12 patients with SPE-PD. Most of the cases were not seriously ill. With early diagnosis by contrast-enhanced chest CT, appropriate antimicrobial therapy and periodontal surgery, resolution of the illness can be expected in most patients.

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      Cross-sectional epidemiological survey of asthma in Jinan, China (pages 313–322)

      DEXIANG WANG, WEI XIAO, DEDONG MA, YUKE ZHANG, QIN WANG, CHUAN Wang, XIULI JI, BAOLONG HE, XIA WU, HONGLI CHEN, YI ZHANG, YUANYUAN JIANG and JIA YIN

      Article first published online: 25 JAN 2013 | DOI: 10.1111/resp.12005

      This cross-sectional epidemiological survey, using a standardized questionnaire and random sampling methods and being conducted in both urban and rural areas at the same time, presents the most updated information on asthma prevalence and asthma control in the population of all ages in Jinan, China.

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      Invasive pulmonary aspergillosis in non-neutropenic patients with and without underlying disease: A single-centre retrospective analysis of 52 subjects (pages 323–331)

      ZHICHU DAI, HAIJIN ZHAO, SHAOXI CAI, YANHUA LV and WANCHENG TONG

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02283.x

      A retrospective cohort study of non-neutropenic patients who had been diagnosed with IPA at our institution over the last 10 years was conducted to investigate epidemiology, clinical characteristics, outcomes, prognosis, and to survey the difference between non-neutropenic patients with and without underlying diseases.

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      Sirtuin 1 activator SRT1720 suppresses inflammation in an ovalbumin-induced mouse model of asthma (pages 332–339)

      TOMOMI ICHIKAWA, RYUJI HAYASHI, KENSUKE SUZUKI, SHINGO IMANISHI, KENTA KAMBARA, SEISUKE OKAZAWA, MINEHIKO INOMATA, TORU YAMADA, YU YAMAZAKI, YUKIKO KOSHIMIZU, TOSHIRO MIWA, SHOKO MATSUI, ISAO USUI, MASAHARU URAKAZE, YUJI MATSUYA, MASAKIYO SASAHARA and KAZUYUKI TOBE

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02284.x

      We investigated the effect of Sirt1 activator SRT1720 on an inflammatory model of asthma. SRT1720 suppressed inflammatory cell infiltration and cytokine production in an OVA-challenged mouse model. SRT1720 and resveratrol also directly suppressed OVA-induced splenocyte proliferation and TNF-α and IL-6 production. SRT1720 has potential as a therapeutic drug for asthma.

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      Aqueous fraction of Sauropus androgynus might be responsible for bronchiolitis obliterans (pages 340–347)

      IZUMI HASHIMOTO, KAZUYOSHI IMAIZUMI, NAOZUMI HASHIMOTO, HIROSHI FURUKAWA, YUKIHIRO NODA, TSUTOMU KAWABE, TOYOHIRO HONDA, TOMOMI OGAWA, MASAKI MATSUO, NAOYUKI IMAI, SATORU ITO, MITSUO SATO, MASASHI KONDO, KAORU SHIMOKATA and YOSHINORI HASEGAWA

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02286.x

      Ingestion of Sauropus androgynus (SA) as dry powder or fresh juice has been reported to induce constrictive bronchiolitis obliterans (BO), but the pathogenesis of this condition is unknown. This study suggests that an aqueous fraction of SA could be responsible for development of SA-induced BO.

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      Differential distribution of lymphatic clearance between upper and lower regions of the lung (pages 348–353)

      RYOKO EGASHIRA, TOMONORI TANAKA, TAKESHI IMAIZUMI, KAZUTAKA SENDA, YOSHINORI DOKI, SHO KUDO and JUNYA FUKUOKA

      Article first published online: 25 JAN 2013 | DOI: 10.1111/resp.12006

      The main lymphatic clearance route differs between the upper and lower regions of the lung. In the upper regions, lymphatic drainage channels predominantly follow a BV distribution. In the lower regions of the lung, lymphatics are predominantly located in the SP area of each lobule.

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      Budesonide/formoterol maintenance and reliever therapy via Turbuhaler versus fixed-dose budesonide/formoterol plus terbutaline in patients with asthma: Phase III study results (pages 354–363)

      TITO ATIENZA, TERESITA AQUINO, MARCELO FERNÁNDEZ, WATCHARA BOONSAWAT, MITSURU KAWAI, TAKAHIDE KUDO, Jan Ekelund, Stefan Ivanov and Lars-Goran Carlsson

      Article first published online: 25 JAN 2013 | DOI: 10.1111/resp.12009

      Budesonide/formoterol maintenance and reliever therapy provides better asthma control, as evidenced by prolonged time to first severe exacerbation, reduced risk of severe asthma exacerbations and improvements in lung function, than the same budesonide/formoterol maintenance treatment plus terbutaline as-needed in patients with asthma uncontrolled with ICS alone.

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      Health care-associated pneumonia in haemodialysis patients: Clinical outcomes in patients treated with narrow versus broad spectrum antibiotic therapy (pages 364–368)

      STEPHANIE PARKS TAYLOR and BRICE T. TAYLOR

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02306.x

      Retrospective comparison of pneumonia in haemodialysis patients treated with broad (HCAP) versus narrow (CAP) spectrum antibiotics. Patients treated with CAP therapy had reduced duration of intravenous antibiotics and shorter hospital stay with no complications or deaths. Results suggest that CAP therapy may be safe for pneumonia in some haemodialysis patients.

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      Enhanced cytotoxic function of natural killer and natural killer T-like cells associated with decreased CD94 (Kp43) in the chronic obstructive pulmonary disease airway (pages 369–376)

      GREG HODGE, VIOLET MUKARO, MARK HOLMES, PAUL N. REYNOLDS and SANDRA HODGE

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02287.x

      NK and NKT-like cells are increased in the airways of subjects with COPD, with decreased expression of the inhibitory receptor CD94 (Kp43) and increased NK cell cytotoxic potential. Investigation of treatment strategies that reduce NK or NKT-like cell numbers and their production of pro-inflammatory mediators in the airway are thus warranted.

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      Ambulatory oximetry fails to predict survival in chronic obstructive pulmonary disease with mild-to-moderate hypoxaemia (pages 377–382)

      JAMES M. TRAUER, CHELSEA A. GIELEN, ALI AMINAZAD and Christopher L. Steinfort

      Article first published online: 25 JAN 2013 | DOI: 10.1111/resp.12010

      Long-term oxygen therapy improves survival in COPD, although the ability of oxygenation parameters to predict outcomes has not been studied. We studied subjects with mild-to-moderate resting hypoxaemia, failing to meet standard qualifying criteria for long-term oxygen therapy. Neither PaO2 nor partial 24-h oxygen saturations below 90% effectively predicted clinical outcomes.

  7. CLINICAL NOTE

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. INVITED REVIEW SERIES: TRANSLATING RESEARCH INTO PRACTICE
    6. REVIEWS
    7. ORIGINAL ARTICLES
    8. CLINICAL NOTE
    9. CORRESPONDENCES
    10. CORRIGENDA
    11. FORTHCOMING MEETINGS
    12. JOURNAL STATISTICS
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      Diagnosis of silicotuberculosis by Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA) (pages 383–384)

      ALVIN H. M. TUNG, JENNY C. L. NGAI, FANNY W. S. KO, BETTY P. K. CHAK, LOUIS CHOW and DAVID S-C. HUI

      Article first published online: 25 JAN 2013 | DOI: 10.1111/resp.12020

  8. CORRESPONDENCES

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. INVITED REVIEW SERIES: TRANSLATING RESEARCH INTO PRACTICE
    6. REVIEWS
    7. ORIGINAL ARTICLES
    8. CLINICAL NOTE
    9. CORRESPONDENCES
    10. CORRIGENDA
    11. FORTHCOMING MEETINGS
    12. JOURNAL STATISTICS
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      Reply (page 386)

      Olalla Castro-Añón, Rafael Golpe and Luis A. Pérez-de-Llano

      Article first published online: 25 JAN 2013 | DOI: 10.1111/resp.12026

  9. CORRIGENDA

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. INVITED REVIEW SERIES: TRANSLATING RESEARCH INTO PRACTICE
    6. REVIEWS
    7. ORIGINAL ARTICLES
    8. CLINICAL NOTE
    9. CORRESPONDENCES
    10. CORRIGENDA
    11. FORTHCOMING MEETINGS
    12. JOURNAL STATISTICS
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      Corrigendum (page 387)

      Article first published online: 25 JAN 2013 | DOI: 10.1111/resp.12017

      This article corrects:

      Year-in-review 2010: Asthma, COPD, cystic fibrosis and airway biology

      Vol. 16, Issue 3, 540–552, Article first published online: 30 MAR 2011

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      Corrigendum (page 387)

      Article first published online: 25 JAN 2013 | DOI: 10.1111/resp.12025

      This article corrects:
  10. FORTHCOMING MEETINGS

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. INVITED REVIEW SERIES: TRANSLATING RESEARCH INTO PRACTICE
    6. REVIEWS
    7. ORIGINAL ARTICLES
    8. CLINICAL NOTE
    9. CORRESPONDENCES
    10. CORRIGENDA
    11. FORTHCOMING MEETINGS
    12. JOURNAL STATISTICS
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      FORTHCOMING MEETINGS (page 388)

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02234.x

  11. JOURNAL STATISTICS

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. INVITED REVIEW SERIES: TRANSLATING RESEARCH INTO PRACTICE
    6. REVIEWS
    7. ORIGINAL ARTICLES
    8. CLINICAL NOTE
    9. CORRESPONDENCES
    10. CORRIGENDA
    11. FORTHCOMING MEETINGS
    12. JOURNAL STATISTICS
    1. You have free access to this content
      JOURNAL STATISTICS (page 388)

      Article first published online: 25 JAN 2013 | DOI: 10.1111/j.1440-1843.2012.02234_2.x

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