Smoking-related emphysema is associated with idiopathic pulmonary fibrosis and rheumatoid lung (pages 1191–1196)
Katerina M. Antoniou, Simon L. Walsh, David M. Hansell, Michael R. Rubens, Katharina Marten, Rachel Tennant, Trevor Hansel, Sujal R. Desai, Nikolaos M. Siafakas, Roland M du Bois and Athol U. Wells
Article first published online: 28 OCT 2013 | DOI: 10.1111/resp.12154
There is a high prevalence of smoking-related emphysema in IPF and rheumatoid lung, often associated with a low pack-year smoking history. Fibrotic abnormalities on HRCT are coarser in smokers with both disorders. These observations raise the possibility of shared mechanisms between fibrogenesis and smoking-related damage.