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Respirology

Cover image for Vol. 19 Issue 2

February 2014

Volume 19, Issue 2

Pages 151–293

  1. EDITORIALS

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES
    4. REVIEWS
    5. CLINICAL PRACTICE GUIDELINES
    6. ORIGINAL ARTICLES
    7. SCIENTIFIC LETTERS
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
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    2. You have free access to this content
  2. INVITED REVIEW SERIES

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES
    4. REVIEWS
    5. CLINICAL PRACTICE GUIDELINES
    6. ORIGINAL ARTICLES
    7. SCIENTIFIC LETTERS
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
    1. Modern Statistical Methods in Respiratory Medicine

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      Models for the analysis of repeated continuous outcome measures in clinical trials (pages 155–161)

      Alysha M. De Livera, Sophie Zaloumis and Julie A. Simpson

      Version of Record online: 25 NOV 2013 | DOI: 10.1111/resp.12217

      Corrected by:

      CORRIGENDUM: Corrigendum

      Vol. 19, Issue 3, 461, Version of Record online: 12 MAR 2014

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  3. REVIEWS

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES
    4. REVIEWS
    5. CLINICAL PRACTICE GUIDELINES
    6. ORIGINAL ARTICLES
    7. SCIENTIFIC LETTERS
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
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      Peripheral venous and arterial blood gas analysis in adults: are they comparable? A systematic review and meta-analysis (pages 168–175)

      Anthony L Byrne, Michael Bennett, Robindro Chatterji, Rebecca Symons, Nathan L Pace and Paul S Thomas

      Version of Record online: 3 JAN 2014 | DOI: 10.1111/resp.12225

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  4. CLINICAL PRACTICE GUIDELINES

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES
    4. REVIEWS
    5. CLINICAL PRACTICE GUIDELINES
    6. ORIGINAL ARTICLES
    7. SCIENTIFIC LETTERS
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
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      Australian standards of care for cystic fibrosis-related diabetes (pages 185–192)

      Peter G. Middleton, Monica Wagenaar, Angela G. Matson, Maria E. Craig, Deborah Jane Holmes-Walker, Tamarah Katz and Shihab Hameed

      Version of Record online: 23 DEC 2013 | DOI: 10.1111/resp.12227

  5. ORIGINAL ARTICLES

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES
    4. REVIEWS
    5. CLINICAL PRACTICE GUIDELINES
    6. ORIGINAL ARTICLES
    7. SCIENTIFIC LETTERS
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
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      Comparable improvements achieved in chronic obstructive pulmonary disease through pulmonary rehabilitation with and without a structured educational intervention: A randomized controlled trial (pages 193–202)

      Felicity C. Blackstock, Kate E. Webster, Christine F. McDonald and Catherine J. Hill

      Version of Record online: 21 NOV 2013 | DOI: 10.1111/resp.12203

      The inclusion of disease-specific group education in pulmonary rehabilitation for COPD was evaluated in a randomized controlled trial. Education incorporating self-management did not result in any additional benefit compared with pulmonary rehabilitation without education. These findings support the delivery of simple exercise-based pulmonary rehabilitation programmes when resources are limited.

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      The Sputum Colour Chart as a predictor of lung inflammation, proteolysis and damage in non-cystic fibrosis bronchiectasis: A case–control analysis (pages 203–210)

      Pieter C. Goeminne, Jennifer Vandooren, Eva A. Moelants, Ann Decraene, Evelyn Rabaey, Ans Pauwels, Sven Seys, Ghislain Opdenakker, Paul Proost and Lieven J. Dupont

      Version of Record online: 29 NOV 2013 | DOI: 10.1111/resp.12219

      Patients with NCFB are characterized by chronic sputum production and an underlying vicious cycle of infection, inflammation and mucus retention. We show that sputum colour assessment is an easy, quick and reliable way that reflects underlying disease severity, proteolytic enzymatic activity/presence and inflammation.

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      Proximal and distal gastro-oesophageal reflux in chronic obstructive pulmonary disease and bronchiectasis (pages 211–217)

      Annemarie L. Lee, Brenda M. Button, Linda Denehy, Stuart J. Roberts, Tiffany L. Bamford, Samantha J. Ellis, Fi-Tjen Mu, Ralf G. Heine, Robert G. Stirling and John W. Wilson

      Version of Record online: 25 DEC 2013 | DOI: 10.1111/resp.12182

      The prevalence of gastro-oesophageal reflux in adults with chronic obstructive pulmonary disease or bronchiectasis is twice as high compared with individuals without lung disease. The findings of this observational study suggest that gastro-oesophageal reflux is a common comorbidity across the disease spectrum in adults with these lung conditions.

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      Detection of viruses and atypical bacteria associated with acute respiratory infection of children in Hubei, China (pages 218–224)

      Zegang Wu, Yan Li, Jian Gu, Hongyun Zheng, Yongqing Tong and Qing Wu

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/resp.12205

      Indirect immunofluorescence assays were performed to detect immunoglobulin M antibodies against nine pathogens to provide an important dataset for use in clinical diagnoses and the development of more effective therapeutic regimens in the future.

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      Inflammatory markers and pulmonary granuloma infiltration in sarcoidosis (pages 225–230)

      Marjeta Terčelj, Barbara Salobir, Mirjana Zupancic, Branka Wraber and Ragnar Rylander

      Version of Record online: 24 DEC 2013 | DOI: 10.1111/resp.12199

      This study demonstrated β-glucan—a fungal cell wall agent—in the lungs of sarcoidosis patients. It also confirmed a positive relationship between β-glucan and domestic fungi exposure. Lung granuloma infiltration correlated inflammatory cytokines except IL-10, an anti-granuloma cytokine.

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      Effect of once-daily indacaterol in a predominantly Chinese population with chronic obstructive pulmonary disease: A 26-week Asia-Pacific study (pages 231–238)

      Wanzhen Yao, Changzheng Wang, Nanshan Zhong, Xiaowen Han, Changgui Wu, Xixin Yan, Ping Chen, Wei Yang, Michelle Henley and Benjamin Kramer

      Version of Record online: 3 JAN 2014 | DOI: 10.1111/resp.12211

      We investigated the effect of indacaterol on FEV1, dyspnoea and health-related quality of life in a predominantly Chinese population diagnosed with moderate-to-severe COPD. Indacaterol proved to be a useful treatment option as it showed effective bronchodilation and improvements in breathlessness and health status in this population.

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      Comparison of clinical characteristics and prognostic factors of combined pulmonary fibrosis and emphysema versus idiopathic pulmonary fibrosis alone (pages 239–245)

      Keishi Sugino, Fumiaki Ishida, Naoshi Kikuchi, Nao Hirota, Go Sano, Keita Sato, Kazutoshi Isobe, Susumu Sakamoto, Yujiro Takai and Sakae Homma

      Version of Record online: 25 NOV 2013 | DOI: 10.1111/resp.12207

      We compared outcome and prognostic factors between CPFE and IPF alone. We found that, survival for individuals with CPFE was significantly worse than that for IPF alone. Especially, CPFE with paraseptal emphysema associated with high esPAP has an extremely poor prognosis.

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      CYFRA 21-1 as a disease severity marker for autoimmune pulmonary alveolar proteinosis (pages 246–252)

      Toru Arai, Yoshikazu Inoue, Chikatoshi Sugimoto, Yasushi Inoue, Keiko Nakao, Naoko Takeuchi, Akiko Matsumuro, Masaki Hirose, Koh Nakata and Seiji Hayashi

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/resp.12210

      Serum CYFRA 21-1 is useful for the diagnosis of autoimmune pulmonary alveolar proteinosis (APAP) by receiver operating characteristic curve analysis and significantly correlated with other disease severity markers of APAP. Serum CYFRA 21-1 might be a predictor of responsiveness to GM-CSF inhalation therapy in APAP.

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      High expression of high-mobility group box 1 in the blood and lungs is associated with the development of chronic obstructive pulmonary disease in smokers (pages 253–261)

      Hsin-Kuo Ko, Wen-Hu Hsu, Chih-Cheng Hsieh, Te-Cheng Lien, Tzong-Shyuan Lee and Yu Ru Kou

      Version of Record online: 24 DEC 2013 | DOI: 10.1111/resp.12209

      Our study showed that in individuals with smoking risk factor, high expression of HMGB1 in the blood and lungs is related to the decline of lung function and appears to be associated with the development of COPD.

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      Association of five genetic variants with chronic obstructive pulmonary disease susceptibility and spirometric phenotypes in a Chinese Han population (pages 262–268)

      Jing Yang, Haixia Zhou, Binmiao Liang, Jun Xiao, Zhiguang Su, Hong Chen, Chunlan Ma, Dengxue Li, Yulin Feng and Xuemei Ou

      Version of Record online: 29 NOV 2013 | DOI: 10.1111/resp.12212

      We demonstrate that variants in HTR4 are associated with COPD in never-smokers, and SNP in AGER are associated with lung function in a Chinese Han population.

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      Pulmonary vascular limitation to exercise and survival in idiopathic pulmonary fibrosis (pages 269–275)

      Mart N. van der Plas, Coen van Kan, Judith Blumenthal, Henk M. Jansen, Athol U. Wells and Paul Bresser

      Version of Record online: 20 NOV 2013 | DOI: 10.1111/resp.12206

      In IPF, pulmonary hypertension is associated with poor prognosis. Cardiopulmonary exercise testing can be used for early detection of a vascular impairment. An increased ventilatory equivalent at anaerobic threshold, a parameter of vascular impairment, was associated with mortality, and may be useful for more accurate prognostic assessment in IPF patients.

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      Nebulization of corticosteroids to asthmatic children: Large variation in dose inhaled (pages 276–279)

      Chris O'Callaghan, Judy A. White and Ahmad Kantar

      Version of Record online: 24 NOV 2013 | DOI: 10.1111/resp.12208

      We investigated if asthmatic children inhale the same proportion of the prescribed dose of fluticasone, beclomethasone dipropionate and flunisolide from the same nebulizer. Results demonstrate that the prescribed dose bears little resemblance to the proportion of drug children inhale and that this is largely dependent on the drug formulation.

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      Altered sputum granzyme B and granzyme B/proteinase inhibitor-9 in patients with non-eosinophilic asthma (pages 280–287)

      Jodie L Simpson, Peter G Gibson, Ian A Yang, John Upham, Alan James, Paul N Reynolds, Sandra Hodge and AMAZES Study Research Group

      Version of Record online: 23 DEC 2013 | DOI: 10.1111/resp.12213

      The non-eosinophilic phenotype of asthma is associated with chronic airway inflammation and airway neutrophilia. The role of granzyme B in NEA is not known. Increased granzyme B expression in NEA may contribute to increased epithelial cell apoptosis, lung injury and chronic inflammation.

  6. SCIENTIFIC LETTERS

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES
    4. REVIEWS
    5. CLINICAL PRACTICE GUIDELINES
    6. ORIGINAL ARTICLES
    7. SCIENTIFIC LETTERS
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
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  7. FORTHCOMING MEETINGS

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES
    4. REVIEWS
    5. CLINICAL PRACTICE GUIDELINES
    6. ORIGINAL ARTICLES
    7. SCIENTIFIC LETTERS
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
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  8. JOURNAL STATISTICS

    1. Top of page
    2. EDITORIALS
    3. INVITED REVIEW SERIES
    4. REVIEWS
    5. CLINICAL PRACTICE GUIDELINES
    6. ORIGINAL ARTICLES
    7. SCIENTIFIC LETTERS
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
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