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Respirology

Cover image for Vol. 19 Issue 4

May 2014

Volume 19, Issue 4

Pages 463–617

  1. EDITORIALS

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. REVIEWS
    6. ORIGINAL ARTICLES
    7. CORRESPONDENCE
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
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  2. SERIES EDITORIAL

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. REVIEWS
    6. ORIGINAL ARTICLES
    7. CORRESPONDENCE
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
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      Update in interventional pulmonology: A prologue to a new review series (page 471)

      Fabien Maldonado, Eric S. Edell, Patrick J. Barron and Rex C. Yung

      Article first published online: 3 APR 2014 | DOI: 10.1111/resp.12289

  3. INVITED REVIEW SERIES

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. REVIEWS
    6. ORIGINAL ARTICLES
    7. CORRESPONDENCE
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
    1. Update in Interventional Pulmonology

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      Achieving competency in bronchoscopy: Challenges and opportunities (pages 472–482)

      David I. Fielding, Fabien Maldonado and Septimiu Murgu

      Article first published online: 1 APR 2014 | DOI: 10.1111/resp.12279

    2. Modern Statistical Methods in Respiratory Medicine

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  4. REVIEWS

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. REVIEWS
    6. ORIGINAL ARTICLES
    7. CORRESPONDENCE
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
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      Predictors of mortality in rheumatoid arthritis-related interstitial lung disease (pages 493–500)

      Deborah Assayag, Molly Lubin, Joyce S. Lee, Talmadge E. King, Harold R. Collard and Christopher J. Ryerson

      Article first published online: 26 DEC 2013 | DOI: 10.1111/resp.12234

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      Intercellular adhesion molecule-1 as a drug target in asthma and rhinitis (pages 508–513)

      Srirupa Mukhopadhyay, Parth Malik, Sunil K. Arora and Tapan K. Mukherjee

      Article first published online: 1 APR 2014 | DOI: 10.1111/resp.12285

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      Biomolecular markers in assessment and treatment of asthma (pages 514–523)

      Farnaz Fatemi, Esmaeil Sadroddiny, Azam Gheibi, Taiebeh Mohammadi Farsani and Gholam Ali Kardar

      Article first published online: 3 APR 2014 | DOI: 10.1111/resp.12284

  5. ORIGINAL ARTICLES

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. REVIEWS
    6. ORIGINAL ARTICLES
    7. CORRESPONDENCE
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
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      Diagnostic performance comparison of the Chartis System and high-resolution computerized tomography fissure analysis for planning endoscopic lung volume reduction (pages 524–530)

      Daniela Gompelmann, Ralf Eberhardt, Dirk-Jan Slebos, Matthew S. Brown, Fereidoun Abtin, Hyun J. Kim, Debby Holmes-Higgin, Sri Radhakrishnan, Felix J.F. Herth and Jonathan Goldin

      Article first published online: 25 FEB 2014 | DOI: 10.1111/resp.12253

      Valve therapy presents an effective treatment in emphysema patients. The presence of CV could undermine the effectiveness of the valve treatment. The Chartis System and CT fissure analysis provide quantification of CV prior to valve therapy. We compare the two methods with respect to CV quantification.

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      Abnormal vocal cord movement treated with botulinum toxin in patients with asthma resistant to optimised management (pages 531–537)

      Malcolm Baxter, Nizam Uddin, Sanjay Raghav, Paul Leong, Kathy Low, Kais Hamza, Peter W. Holmes, Garun Hamilton, Dominic Thyagarajan, Ken Lau and Philip G. Bardin

      Article first published online: 23 MAR 2014 | DOI: 10.1111/resp.12271

      Abnormal vocal cord movement may contribute to refractory asthma and temporary partial paralysis with botulinum toxin may be an effective local treatment that improves asthma control. Although a placebo effect cannot be ruled out in this study, injection of botulinum toxin appears to be useful and randomised studies are merited.

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      Measurement of oxygen concentration delivered via nasal cannulae by tracheal sampling (pages 538–543)

      Andrew O'Reilly Nugent, Paul T. Kelly, Josh Stanton, Maureen P. Swanney, Bruce Graham and Lutz Beckert

      Article first published online: 24 MAR 2014 | DOI: 10.1111/resp.12268

      A new technique for non-invasively measuring tracheal oxygen concentration is described. We confirm that 2 L/min of oxygen delivered via a nasal cannula will result in tracheal inspired oxygen concentrations between 0.284 and 0.296. We also describe clinically important variations of implications from differing breathing patterns on the inspired oxygen concentration.

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      Diagnostic utility of VEGF mRNA and SP1 mRNA expression in bronchial cells of patients with lung cancer (pages 544–548)

      Na Cha, Ming Lv, Yu-Jie Zhao, Di Yang, En-Hua Wang and Guang-Ping Wu

      Article first published online: 24 MAR 2014 | DOI: 10.1111/resp.12272

      Cellular expression (by RT-PCR) and clinical utility of VEGF mRNA and SP1 mRNA were evaluated in cells obtained by bronchial brushing in patients with or without lung cancer. VEGF mRNA and SP1 mRNA may be useful as an ancillary tool for cytological diagnosis and detection of early-stage lung cancer.

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      Development and validation of a clinical risk score for predicting drug-resistant bacterial pneumonia in older Chinese patients (pages 549–555)

      Hon Ming Ma, Margaret Ip, Jean Woo and David SC Hui

      Article first published online: 24 MAR 2014 | DOI: 10.1111/resp.12267

      This prospective cohort study shows that risk stratification with a clinical risk score is better than the HCAP definition in predicting drug-resistant bacterial pneumonia. The presence of bronchiectasis or recent hospitalization is the most important indication of starting empirical broad-spectrum antibiotics.

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      Predictors of the pathogenicity of methicillin-resistant Staphylococcus aureus nosocomial pneumonia (pages 556–562)

      Kentaro Nagaoka, Katsunori Yanagihara, Yosuke Harada, Koichi Yamada, Yohei Migiyama, Yoshitomo Morinaga, Koichi Izumikawa, Hiroshi Kakeya, Yoshihiro Yamamoto, Masaharu Nishimura and Shigeru Kohno

      Article first published online: 8 APR 2014 | DOI: 10.1111/resp.12288

      Patients with a hospital-acquired ‘true’ MRSA-nosocomial pneumonia differed in severity, radiological feature and microbiological findings from patients with a hospital-acquired pneumonia with MRSA colonization. We identify several clinical factors to differentiate true MRSA nosocomial pneumonia in patients with MRSA identfification.

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      Exhaled breath condensate pH decreases during exercise-induced bronchoconstriction (pages 563–569)

      Andras Bikov, Gabriella Galffy, Lilla Tamasi, Dora Bartusek, Balazs Antus, Gyorgy Losonczy and Ildiko Horvath

      Article first published online: 25 FEB 2014 | DOI: 10.1111/resp.12248

      Exhaled breath condensate (EBC) pH was measured in asthmatics with and without exercise-induced bronchoconstriction (EIB) as well as healthy individuals before and after physical exercise. EBC pH decreased only in EIB-positive asthmatics and was related to the degree of bronchospasm suggesting a possible role of airway pH reduction in EIB.

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      Sleep disordered breathing and airway disease in primary ciliary dyskinesia (pages 570–575)

      Francesca Santamaria, Maria Esposito, Silvia Montella, Elena Cantone, Carmine Mollica, Sara De Stefano, Virginia Mirra and Marco Carotenuto

      Article first published online: 24 MAR 2014 | DOI: 10.1111/resp.12273

      Parents of children with primary ciliary dyskinesia may underestimate nocturnal sleep disordered breathing. As nocturnal desaturation is associated with lung function and structural abnormalities, sleep disordered breathing may significantly contribute to pulmonary morbidity in primary ciliary dyskinesia.

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      Predicting weaning and extubation outcomes in long-term mechanically ventilated patients using the modified Burns Wean Assessment Program scores (pages 576–582)

      Jung-Rern Jiang, Shiao-Yu Yen, Jung-Yien Chien, Hsiao-Chien Liu, Yi-Ling Wu and Ching-Hui Chen

      Article first published online: 24 MAR 2014 | DOI: 10.1111/resp.12266

      We used a m-BWAP scoring instrument for LTMV to predict extubation outcome. Correcting the factors affecting m-BWAP improves chance of weaning from ventilator. Application of m-BWAP for patients with LTMV can help predict successful weaning and extubation outcomes more accurately.

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      Cystatin C: A potential biomarker for pulmonary arterial hypertension (pages 583–589)

      Brett E. Fenster, Luis Lasalvia, Joyce D. Schroeder, Jamey Smyser, Lori J. Silveira, J. Kern Buckner and Kevin K. Brown

      Article first published online: 14 MAR 2014 | DOI: 10.1111/resp.12259

      We examined the ability of cystatin C (CysC) to predict the presence of pulmonary arterial hypertension (PAH) and found that CysC strongly correlates with right ventricular systolic pressure, function and morphology. Furthermore, CysC performed comparably with the existing biomarkers brain natriuretic peptide (BNP) and N-terminal BNP.

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      Association of group component genetic variations in COPD and COPD exacerbation in a Japanese population (pages 590–595)

      Takeo Ishii, Takashi Motegi, Koichiro Kamio, Akihiko Gemma and Kozui Kida

      Article first published online: 16 APR 2014 | DOI: 10.1111/resp.12277

      Genetic variations of group component, a vitamin D-related gene, are associated with COPD, including exacerbation frequency. These polymorphisms may affect exacerbation susceptibility, leading to COPD progression in a Japanese population.

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      Randomized trial of ‘intelligent’ autotitrating ventilation versus standard pressure support non-invasive ventilation: Impact on adherence and physiological outcomes (pages 596–603)

      Julia L. Kelly, Jay Jaye, Rachel E. Pickersgill, Michelle Chatwin, Mary J. Morrell and Anita K. Simonds

      Article first published online: 24 MAR 2014 | DOI: 10.1111/resp.12269

      Non-invasive ventilation delivered by a ventilator with volume-assured pressure support mode and the ability to ‘learn’ from the patient's wake breathing pattern (iVAPS) was as effective as standard PS set up by a skilled health-care professional and produced better overnight adherence in nocturnal hypoventilation patients naive to previous NIV.

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      Comparison of the modified shuttle walk test and cardiopulmonary exercise test in sarcoidosis (pages 604–607)

      Sally de Boer, John Kolbe and Margaret L. Wilsher

      Article first published online: 25 MAR 2014 | DOI: 10.1111/resp.12276

      This study compares a walk test with a full cardiopulmonary exercise test in assessing exercise capacity in sarcoidosis. Given the mixed nature of pulmonary impairment, it is important to determine the performance of the test specifically in this disease. The walk test could be an important addition to the monitoring of sarcoidosis patients.

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      Elevated plasma YKL-40 as a prognostic indicator in patients with idiopathic pulmonary arterial hypertension (pages 608–615)

      Guo Chen, Tao Yang, Qing Gu, Xin-Hai Ni, Zhi-Hui Zhao, Jue Ye, Xian-Min Meng, Zhi-Hong Liu, Jian-Guo He and Chang-Ming Xiong

      Article first published online: 1 APR 2014 | DOI: 10.1111/resp.12283

      The ability of YKL-40, an inflammation and remodelling marker, to predict prognosis of IPAH was explored. Plasma YKL-40 was significantly elevated in IPAH patients compared with healthy controls. Patients with higher YKL-40 had increased hemodynamic severity and right heart dysfunction. After follow-up, YKL-40 independently predicted clinical worsening in IPAH.

  6. CORRESPONDENCE

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. REVIEWS
    6. ORIGINAL ARTICLES
    7. CORRESPONDENCE
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
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      Prevalence of COPD (page 616)

      Katsunori Kagohashi, Hiroaki Satoh and Koichi Kurishima

      Article first published online: 16 APR 2014 | DOI: 10.1111/resp.12275

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      Reply (page 616)

      Yasuo Sekine

      Article first published online: 16 APR 2014 | DOI: 10.1111/resp.12274

  7. FORTHCOMING MEETINGS

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. REVIEWS
    6. ORIGINAL ARTICLES
    7. CORRESPONDENCE
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
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  8. JOURNAL STATISTICS

    1. Top of page
    2. EDITORIALS
    3. SERIES EDITORIAL
    4. INVITED REVIEW SERIES
    5. REVIEWS
    6. ORIGINAL ARTICLES
    7. CORRESPONDENCE
    8. FORTHCOMING MEETINGS
    9. JOURNAL STATISTICS
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