Salivary flow rates among women diagnosed with benign and malignant tumors
Article first published online: 4 MAR 2013
©2013 Special Care Dentistry Association and Wiley Periodicals, Inc.
Special Care in Dentistry
Volume 33, Issue 3, pages 102–110, May/June 2013
How to Cite
Napeñas, J. J., Miles, L., Guajardo-Streckfus, C. and Streckfus, C. F. (2013), Salivary flow rates among women diagnosed with benign and malignant tumors. Special Care in Dentistry, 33: 102–110. doi: 10.1111/scd.12017
- Issue published online: 21 APR 2013
- Article first published online: 4 MAR 2013
- Avon Breast Cancer Foundation. Grant Number: #07-2007-071
- Komen Foundation. Grant Number: KG080928
- Gillson-Longenbaugh Foundation
- Texas Ignition Fund
The purpose of this study was to compare salivary flow rates (SWS) among patients diagnosed with benign and varying malignant solid tumors with the comparison group, prior to the initiation of any treatment. An evaluation of the results found that mean baseline SWS flow rates were higher for healthy patients (1.55 ml/min) when compared to patients diagnosed with benign tumors (1.13 ml/min), breast cancer (1.09 ml/min), and reproductive carcinomas (0.94 ml/min). The overall model (F = 7.76; p < .001) and the Dunnett's post hoc analyses were statistically significant at the p < .001 level. Additionally, medications, race, and season of the year had significant effects on mean SWS flow rates. The results suggest that salivary secretion is lower among both benign and malignant tumor subjects prior to the initiation of treatment. Salivary evaluations of subjects prior to treatment may be useful in identifying individuals at risk for oral complications during chemotherapy.