Transition to Dialysis: Controversies in its Timing and Modality
Quality of Life and Mental Health Related to Timing, Frequency and Dose of Hemodialysis
Article first published online: 19 SEP 2013
© 2013 Wiley Periodicals, Inc.
Seminars in Dialysis
Volume 26, Issue 6, pages 697–701, November–December 2013
How to Cite
Cohen, S. D. and Kimmel, P. L. (2013), Quality of Life and Mental Health Related to Timing, Frequency and Dose of Hemodialysis. Seminars in Dialysis, 26: 697–701. doi: 10.1111/sdi.12124
- Issue published online: 18 NOV 2013
- Article first published online: 19 SEP 2013
The perceived quality of life (QOL) and mental health of dialysis patients can have a significant impact on clinical outcomes in the end-stage renal disease (ESRD) population. There is growing interest in increasing dialysis frequency, dose and duration to achieve more adequate dialysis clearance, particularly of middle molecules. Over the past decade, there has been an interest in earlier initiation of dialysis; however, the results of the IDEAL study call this practice into question, and showed no difference in QOL scores between the early-start and later start dialysis patients. There are inconsistent results regarding the impact of increased dialysis frequency and dose on patients' perceived health-related QOL (HRQOL). Some studies of daily nocturnal dialysis patients show a positive impact on QOL, while others show no significant difference. The disparate outcomes may be partly related to differences in the demographic characteristics of the study populations and the specific questionnaires used to measure HRQOL. Additional research is necessary to determine whether changes in dialysis frequency, timing, and dose can positively or negatively impact patients' perceptions of their QOL and mental health.