Efficacy of combined antiviral therapy with lamivudine and tenofovir in a liver transplanted girl with de novo hepatitis B virus infection


Correspondence to:

Raffaele Iorio, MD, Pediatric Hepatology, Department of Pediatrics, University of Naples Federico II, Via S. Pansini 5, Naples 80131, Italy

Tel/Fax: +390817464337

E-mail: riorio@unina.it


The management of de novo hepatitis B (HBV) infection in children after liver transplantation is not well defined. Because this infection may induce severe liver disease in the graft liver, an efficient antiviral therapy is desirable. Here, we describe the favorable viral outcome observed in a liver transplanted girl with de novo HBV infection following combination therapy with lamivudine and tenofovir.