Reactivation of Chagas disease in a bone marrow transplant patient: case report and review of screening and management

Authors

  • K.M.U. Guiang,

    1. Division of Infectious Diseases, University of Southern California Keck School of Medicine, Los Angeles, California, USA
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  • P. Cantey,

    1. Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
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  • S.P. Montgomery,

    1. Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
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  • S. Ailawadhi,

    1. Division of Hematology and Oncology, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA
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  • Y. Qvarnstrom,

    1. Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
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  • T. Price,

    1. Division of Hematology and Oncology, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA
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  • E. Blodget

    Corresponding author
    1. Division of Infectious Diseases, University of Southern California Keck School of Medicine, Los Angeles, California, USA
    • Correspondence to:

      Emily Blodget, MD, LA County-USC Medical Center, 2020 Zonal Ave. Room 436, Los Angeles, CA 90033, USA

      Tel: 562 230 6954

      Fax: 323 226 7726

      E-mail: eblodget@usc.edu

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Abstract

We report a patient with an autologous stem cell transplant and history of residence in a Chagas disease (CD) endemic area who developed Chagas reactivation after induction for transplantation. We recommend that patients at risk for CD be screened before transplantation, and patients found to have chronic infection be monitored for reactivation post transplant.

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