Tropical medicine and international health
There is evidence of an increased pfmdr1 copy number in Plasmodium falciparum isolates in Suriname – an early warning sign for emerging artemisinin drug resistance in South-America. 796–799.
Plasmodium falciparum gametocytemia is common in India and varies by region. Adults contribute substantially to the reservoir for potential transmission. Predictive modeling to generate a clinical algorithm for detecting gametocytemia did not provide sufficient discrimination for targeting interventions. 800–809.
The high sporozoite rate and HBF of An. culicifacies E indicate that it plays an important role in malaria transmission in Odisha, India. Control measures against An. culicifacies E at an early stage are needed. 810–821.
Diabetes considerably increases risk of early mortality during TB treatment. The effect may not be explained by greater severity of TB, but could be due to impaired TB treatment response. 822–829.
An investigation of the temporal and regional variability of the 2001–2002 dengue outbreak in Havana City illustrates the potential impact of climatological events on disease spread and highlights the need to be well-prepared for potentially worsening disease spread in the aftermath of hurrcanes/typhoons. 830–838.
Spatiotemporal patterns of Ae.aegypti in Cairns are complex and demonstrate associations with temperature and rainfall, and spatial autocorrelation. Vector density maps identify high transmission zones for targeting dengue interventions. 839–849.
A seroprevalence study found that 10% of Gambian children had evidence of previous Q-fever-infection. This suggests significant exposure to Q-fever, which could be a relevant clinical cause of non-malaria febrile episodes. 850–853.
A modified local tool to dispose of child faeces may contribute to improving environmental sanitation and health. 854–860.
Contracting with NGOs appears to improve the coverage, quality, and equity of primary health care in urban Bangladesh and likely performed better than internal contracting. 861–870.
A new pediatric severity-of-illness score for resource-limited settings is designed to identify hospitalized patients at highest risk of death and facilitate urgent clinical re-evaluation. 871–878.
Task-shifting routine vital signs and a new inpatient severity-of-illness score can lead to more vital sign assessments and clinician referrals for patient evaluation. 879–886.
The primary direction of internal health worker migration is from the faith-based to the public sector, due to management, training, employee engagement and workload. 887–897.
Community health workers trained for a short period but effectively supervised proved competent in identifying and referring sick newborns in Uganda. 898–906.
An observational study of HIV/TB co-infected patients in rural Kenya found that early antiretroviral therapy (within 8 weeks) was associated with improved survival in patients with CD4 counts <50 cells/ul. 907–914.