Tropical Medicine & International Health

Migrant health

Despite their higher exposure to zoonoses and problems caused by extreme climatic conditions, mobile pastoralists are virtually excluded from health care systems since the provision of social services adapted to their way of life is challenging. Based on the needs of mobile pastoralists and the necessities of development, interdisciplinary research has considerably contributed to better understanding of their situation and their problems. 1044–1052

Child health

Children from resource-poor countries are particularly vulnerable to climate change, and suffer nearly all of its health-related consequences. Paediatricians can take specific actions to protect their patients from these effects. 1053–1056

In Dhaka, newborns of mothers with bacterial reproductive tract colonization or histologically confirmed chorioamnionitis are at a 111% higher risk of developing sepsis than newborns of non-colonized or non-infected mothers. 1057–1064

A study conducted over a 10-year period in four large HIV programs highlights the need to diagnose and provide early care to HIV-infected children in sub-Saharan Africa to reduce mortality. 1065–1074

Asymptomatic cryptococcal antigenaemia was detectable in 5% of ART clinic attendees with CD4 counts ≤100 cells/microL. The point-of-care lateral flow assay showed good agreement with the conventional CRAG assay. 1075–1079


Patients with diabetes mellitus and/or hypertension in rural sub-Saharan Africa may be less liable to have albuminuria than similar patients in urban areas. 1080–1084


22 For preschool children, praziquantelformulations that can be divided into 4 parts (to give 150 mg increments) are preferable for children weighing less than 11 kg; the same dosing can be applied with 600 mg praziquantel formulations that can be divided into 4 quarters or 2 halves from 11 kg body weight. 1085–1089

106Aggressive praziquantel therapy given to women with urogenital schistosomiasis indicates that it may play a key role in decreasing HIV susceptibility in people living in regions where S. haematobium is endemic. 1090–1096


The dengue seroprevalence in the adult population in Hong Kong was 1.6%. Visiting Southeast Asia was the only independent predictor. 1097–1102

Chagas disease

Highly correlated results between T. cruzi single or pooled recombinant proteins indicate usefulness of recombinant antigens for Chagas diagnosis. High KI values between TSSAVI and the other recombinant proteins suggest that in Argentinian patients the infection may be caused by T. cruzi II, V and/or VI lineages. 1103–1109


In 4 African countries, higher socioeconomic status was associated with HIV testing at Voluntary Counselling and testing facilities, compared with testing at health facilities or not testing. 1110–1118


Genetic associations with tuberculosis in the Sudanese population had never been studied. In a cohort of 191 patients the CCL5 -28G and the IL-10 -592A alleles were associated with the development of tuberculosis in Sudan. 1119–1127

Treatment of MDR-TB among HIV-infected people on ART is hugely demanding for patients, caregivers, and families. Current regimens and case-holding strategies are resource-intensive and require high levels of support from family and lay caregivers to encourage patient adherence and retention in care. 1128–1133

The Xpert MTB/RIF Assay is a rapid and accurate diagnostic test for detecting pulmonary TB in obstetric and gynecological inpatients, where TB co-morbidity with communicable and non-communicable conditions is common. 1134–1140

The content of anti-TB drugs supplied through RNTCP in 8 districts in Tamil Nadu was generally good except for cycloserine, whose deterioration can be minimised by storage in refrigerators. 1141–1144


Impairment at diagnosis was the main risk factor for neurological worsening after leprosy treatment. Early diagnosis and prompt treatment of reactional episodes remain the main means of preventing physical disabilities. 1145–1153

Public health policy

Low- and middle-income countries need to make better use of routinely collected data to improve coverage, quality and effectiveness of their public health programmes and the health of their people. 1154–1156

The findings from the recent global hepatitis survey are a stark reminder of the persistence of the danger caused by unnecessary injections. This raises the question of whether progress is being made on reducing unnecessary injections, which WHO identifies as a key strategy for reducing injection-associated disease transmission. 1157–1159