Endometriosis: Science and Practice Editors Linda C Giudice, Johannes LH Evers, David L Healey Wiley-Blackwell, 2012 ISBN: 978-1444332131, Hardback, 600 pages, £145.00



As the title suggests, this textbook provides a comprehensive account of all facets of endometriosis ranging from history, epidemiology and pathogenesis to medical and surgical management options. The book is edited by distinguished authors and has contributions from eminent scientists and specialists from across the world.

The book comprises of 10 parts and 56 chapters. The first five parts include chapters on basic sciences fundamental to the study of endometriosis. The remaining five parts cover clinical aspects of endometriosis including diagnosis and therapies. Each chapter has valuable updates on recent developments, which makes this textbook a useful reference book for trainees and clinicians who want to read about a particular aspect of endometriosis.

Some chapters give a detailed account of basic science, pathophysiology and animal research related to endometriosis and contain a detailed description of molecular and cell biology, which will be useful for those undertaking research in the field of endometriosis. However, as a clinician, I was particularly interested in the clinical sections on diagnosis and treatments. The chapters on non-invasive diagnostic modalities such as biomarkers, proteomics and transcriptomics provide an insight into new tests that are evolving. Part 7 contains four evidence-based chapters on medical therapies for pain. The chapter on alternative medical therapies, particularly the use of statins, makes a very interesting read and it provides a detailed account of how statins may have a potential use in the future for treatment of this enigmatic disease. The authors have made fascinating observations about the effect of statins on inflammation, immune responses and oxidative stress that can lead to improvement in symptoms of endometriosis. Part 8 on surgical therapies has well-written chapters on surgical treatments for endometriosis in different locations in the pelvis and includes a detailed description of surgical techniques. The final part comprises nine chapters on important subjects including cancer, sexuality and psychosomatic aspects in endometriosis that are relevant in day-to-day practice.

This book is an excellent resource for trainees who want to further their knowledge of endometriosis as well as senior doctors who want to keep up-to-date with recent advances in diagnosis and management of endometriosis.