Non-cervical human papillomavirus-related disease

Authors

  • Jonathan Lippiatt MD MRCOG,

    Subspecialty Trainee in Gynaecological Oncology, Corresponding author
    1. South East Wales Gynaecological Oncology Centre, University Hospital Llandough, Cardiff, UK
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  • Ned Powell PhD,

    Senior Lecturer
    1. HPV Research Group, Institute of Cancer and Genetics, Cardiff University School of Medicine, University Hospital of Wales, Cardiff, UK
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  • Amanda Tristram MD MRCOG

    Senior Clinical Lecturer
    1. Institute of Cancer and Genetics, Cardiff University School of Medicine, University Hospital of Wales, Cardiff, UK
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Abstract

Key content

  • Human papillomavirus (HPV) is associated with neoplastic disease at sites other than the cervix.
  • Cancer caused by HPV may behave differently to other cancers at the same site.
  • The presence of HPV alone is not sufficient to demonstrate a causal association.
  • HPV vaccination has the potential to impact on disease burden beyond cervical cancer.

Learning objectives

  • To understand the spectrum of disease caused by HPV.
  • To review the management of HPV-associated disease in pregnancy.
  • To be aware that future research into HPV-related disease may alter management.

Ethical issues

  • What advice should women be given regarding their sexual partners?
  • Should boys be offered HPV vaccination?

Ancillary