Figure S1. Plasmid vector overview.

Figure S2. Screening overview.

Figure S3. Hygromycin resistance silencing.

Figure S4. Seedling phenotype of i-irpds and i-ovipt.

Figure S5. LhGR efficiency screening.

Figure S6. Stability of dexamethasone under different temperature and light conditions.

Figure S7. DEX application method.

Figure S8. pOp6/LhGR system in Nicotiana attenuata under glasshouse conditions.

Figure S9. Spatial characteristics of the pOp6/LhGR system after induction with dexamethasone-containing lanolin paste.

Figure S10. pOp6/LhGR system in Nicotiana attenuata – hydroponic culture.

Figure S11. Inducible gene silencing in the field.

Figure S12. Dexamethasone treatments do not influence plant growth.

Figure S13. Chlorophyll content of leaves with different bleaching grades.

Figure S14. Subtle cytokinin induction in the field does not change plant growth.

Figure S15. Dexamethasone treatment does not affect Tupiocoris notatus performance.

Figure S16. Quantification method for Tupiocoris notatus damage.

Figure S17. Dexamethasone treatment does not affect Manduca sexta performance.

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Table S1. Temperature conditions at the Utah field site on one day within the field season (4 p.m., 2 June 2012).

Table S2. Sequences of primers used for qPCR.

Table S3. Sequences of primers used for PCR.

Table S4. Multireaction-monitoring settings for dexamethasone quantification in negative ionization mode.

Table S5. Multireaction-monitoring settings for cytokinin quantification in positive ionization mode.

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