Arabidopsis Exocyst Subcomplex Containing Subunit EXO70B1 Is Involved in Autophagy-Related Transport to the Vacuole (pages 1155–1165)
Ivan Kulich, Tamara Pečenková, Juraj Sekereš, Ondřej Smetana, Matyáš Fendrych, Ilse Foissner, Margit Höftberger and Viktor Žárský
Article first published online: 17 SEP 2013 | DOI: 10.1111/tra.12101
Exocyst, an octameric complex known to tether exocytotic vesicles to the plasma membrane, is found to be involved in the Golgi-independent autophagic membrane transport into the vacuole directed by EXO70B1 subunit—one of 23 EXO70 paralogs in Arabidopsis. EXO70B1/ATG8f positive compartments are internalized into the central vacuole and exo70B1 mutants show decreased number of intravacuolar autophagic bodies, increased nitrogen starvation susceptibility, ectopic hypersensitive response mediated by salicylic acid accumulation and vacuole anthocyanin accumulation defects.