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Background

Demand for plasma-derived products, and consequently plasmapheresis donors, continues to increase. This study aims to identify the factors that facilitate the persuasion success of conversations with whole blood (WB) donors to convert to plasmapheresis donation within a voluntary nonremunerated context.

Study Design and Methods

Surveys were sent to WB donors after a plasmapheresis conversion conversation with a blood collection agency (BCA) staff member: in center (Sample 1) or via a call center (Sample 2). Participants reported the number of donor-initiated and BCA-initiated conversations about plasma, experienced in the prior 12 months. Perceptions of the most recent conversation, donor oriented and conversion oriented, were also reported. The BCA provided WB donation history for the prior 5 years. Participants' intentions to make a first plasmapheresis donation were captured and any subsequent plasmapheresis donation was objectively recorded.

Results

Conversion rates were higher for in-center than call center–based conversations. For both samples, path analyses revealed that intentions are associated with conversion. Prior WB donations are negatively associated, while donor-initiated and donor-orientated conversations are positively associated with conversion intentions. Results for agent-initiated conversations and conversion-orientated conversations were mixed across samples.

Conclusion

Converting suitable WB donors to plasmapheresis is best achieved early in the donor's career using face-to-face conversations with collection center staff. BCAs should facilitate donor-initiated conversations through promotional campaigns that encourage donors to approach staff. Conversations that focus on donors' needs and welfare more effectively encourage conversion intentions than those perceived as pushing the requirements of the BCA.