Deborah L. Simpson, Gregory G. Burton and Lydia E. Hambrook
Background – Pyoderma gangrenosum (PG) is a rare disease, which, to the best of the authors' knowledge, has been the subject of only one case report in the peer-reviewed veterinary literature. Hypothesis/Objectives – To describe the history, clinical signs, diagnostic findings and treatment outcome in two cases of canine PG. Conclusions and clinical importance – Pyoderma gangrenosum is a rare disease distinguished by rapid progression of painful, necrolytic, cutaneous ulcers with irregular, violaceous undermined borders. Azathioprine with glucocorticoids may lead to a better outcome than ciclosporin and glucocorticoids (currently the first-line treatment in humans and the only reported treatment in dogs).